EditorsGita Ganguly MukherjeeDGO MD FICOG FICMCH FRCOG
Senior Consultant Gynecologist Former Professor and Head Department of Obstetrics and Gynecology RG Kar Medical College,
Kolkata, West Bengal, India
President RN Ganguly Foundation
Kolkata, West Bengal, India
BN ChakravartyMO FRCOG DSc
Director Institute of Reproductive Medicine
Kolkata, West Bengal, India
7Contributors
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IUI: Intrauterine Insemination
First Edition: 2012
9789350258866
Printed at
5Dedicated to
The childless couples
Who came to us with a
Glitter of hope in their eyes
To achieve Parenthood
by
Intrauterine Insemination (IUI)
- Abha Sarkar mbbs dgo md fimsa ficmch ficog
- Ex-Professor and Head
- Institute of Postgraduate Medical
- Education and Research and Seth Sukhlal Karmani Memorial Hospital
- Consultant
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Alka Kriplani md frcog
- Professor and Consultant
- Gyne-endoscopy and Gyne-endocrinology
- Department of Obstetrics and Gynecology
- All India Institute of Medical Sciences
- New Delhi, India
- Anima Biswas mbbs frcog phd ficog
- Ex-Professor and Head
- Department of Obstetrics and Gynecology
- RG Kar Medical College
- Kolkata, West Bengal, India
- Anupama Ashok md
- Fellowship in Reproductive Medicine
- Senior Registrar
- Reproductive Medicine
- Ankur Healthcare Pvt Ltd
- Bengaluru, Karnataka, India
- Arati Biswas mbbs md
- Professor and Head
- Department of Obstetrics and Gynecology
- National Medical College
- Kolkata, West Bengal, India
- Arati Ghosh mbbs frcog
- Ex-Professor
- RG Kar Medical College
- Kolkata, West Bengal, India
- Arup Kumar Majhi md dnb ficog
- Professor
- Department of Obstetrics and Gynecology
- RG Kar Medical College
- Kolkata, West Bengal, India
- Bani Kumar Mitra dgo frcog
- Director
- Surgey Center
- Kolkata, West Bengal, India
- Betty Thomas md dnb fnb
- (Reprodutive Medicine)
- Consultant
- Madras Medical Mission
- Chennai, Tamil Nadu, India
- Bhaskar Pal dgo md dnbe ficog frcog
- Senior Consultant Gynecologist
- Apollo Gleneagles Hospital
- Kolkata, West Bengal, India
- Bibaswan Ghosh mbbs fais frcs
- Consultant Andrologist/Urologist
- Biman Ghosh dgo frcog
- Head
- Department of Obstetrics and Gynecology
- Pearless Hospital
- Consultant
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Biswapati Mukherjee dgo md
- Assistant Professor
- Department of Obstetrics and Gynecology
- Institute of Child Health
- BN Chakravarty mo frcog dsc
- Director
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Bulbul Raichaudhuri mbbs dgo md ficog
- Consultant, Gynecologist and Obstetrician
- Kolkata, West Bengal, India
- President
- Association of Medical Women in India
- West Bengal, India
- Chaitali Dutta Roy mbbs md ficog
- Associate Professor
- Department of Obstetrics and Gynecology
- Education and Research and Seth Sukhlal Karmani Memorial Hospital
- Kolkata, West Bengal, India
- Debjyoti Karmakar md dnb
- Senior Resident
- Department of Obstetrics and Gynecology
- All India Institute of Medical Sciences
- New Delhi, India
- Deepak Goenka mbbs md
- Director
- Institute of Human Reproduction
- Guwahati and Kolkata, India
- Dhiraj Gada md
- Director, Gada Life ART Centre
- President, ISAR 2010-2012
- Member, Scientific Committee IFFS
- Member, Board of Directors, IFFS
- Chairman, LOC IFFS India 2016
- Kotdawala Women's Clinic
- Ahmedabad, Gujarat, India
- Fessy Louis T dgo dnb mnams micog
- IVF Coordinator and Endoscopic Surgeon
- Centre for Infertility Management and Assisted Reproduction
- Kochi, Kerala, India
- Firuza Rajesh Parikh md dgo dfp fcps dip nbe
- Director
- Department of Assisted Reproduction and Genetics
- Jaslok Hospital and Research Centre
- Mumbai, Maharashtra, India
- Editor-in-Chief
- Fertility and Sterility Indian Edition
- Gita Ganguly Mukherjee dgo md ficog ficmch frcog
- Senior Consultant Gynecologist
- Former Professor and Head
- Department of Obstetrics and Gynecolog
- RG Kar Medical College
- Kolkata, West Bengal, India
- President
- RN Ganguly Foundation
- Kolkata, West Bengal, India
- Guruprasad Kalthur
- Division of Reproductive Medicine
- Kasturba Medical College
- Manipal University
- Manipal, Karnataka, India
- Hasibul Hasan Siraji mbbs dgo md fnb
- Assistant Professor
- Department of Obstetrics and Gynecology
- Medical College
- Kolkata, West Bengal, India
- Hrishikesh Pai md fcps ficog msc
- Treasurer of FOGSI
- Vice President ISAR
- Past President Mumbai, OBGYN Society
- Past Senior VP FOGSI,
- Past President Indian Society of Gynecological Endoscopists
- Consultant
- IVF Expert at Fortis Bloom IVF Centre
- New Delhi/Mohali/Vashi and Lilavati Hospital
- Mumbai, Maharashtra, India
- Jagdishwari Mishra mbbs dgo md ms frcog ficog
- Retired Professor and Head
- Patna Medical College and Hospital
- Patna, Bihar, India
- Jaideep Malhotra md ficog
- Malhotra Nursing and Maternity Home (P) Ltd.
- Agra, Uttar Pradesh, India
- Jayeeta Samanta ms(obg) dnb fnb (Reproductive Medicine)
- Consultant – IVF
- Bourn Hall Clinic
- Kochi, Kerala, India
- Jisha Rajendran md
- Centre for Infertility Management and Assisted Reproduction
- Kochi, Kerala, India
- Kamini A Rao dgo dorcp dchmch (uk) frcog (uk) ficog fais pgdmle (law)
- President, FOGSI-2001
- Medical Director
- Bangalore Assisted Conception Center
- (An ISO 9002 Organization)
- Karnataka, India
- LK Pandey dgo md ficog
- Professor
- Department of Obstetrics and Gynecology
- Banaras Hindu University
- Varanasi, Uttar Pradesh, India
- Madhavi Panpalia mbbs ms
- Clinical Associate
- Department of Assisted Reproduction and Genetics
- Jaslok Hospital and Research Centre
- Mumbai, Maharashtra, India
- Mahamaya Sarkar dgo md ficog
- Retired Professor
- Consultant Obstetrician and Gynecologist
- Manju Gita Mishra dgo ms fics ficog fiams ficmch
- Ex-Professor
- Obstetrics and Gynecology
- Patna Medical College and Hospital
- Patna, Bihar, India
- Senior Consultant
- MGM Hospital and Research Centre
- Patna, Bihar, India
- Chairperson
- Medical Education Committee
- FOGSI, 2007-2009
- Manjusree Chakrabarty dgo md
- Consultant
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Mayukh Roy mbbs dgo
- Medical Superintendent
- ESI Hospital
- Sealdah, West Bengal, India
- Mekala D md dgo
- Consultant Infertility Specialist
- BACC Health Care Private Limited
- Karnataka, India
- ML Goenka mbbs dgo
- Director
- Institute of Human Reproduction
- Guwahati and Kolkata, India
- Mausumi De Banerjee dgo dnb micog
- Consultant Gynecologist
- Kolkata, West Bengal, India
- Mumtaz Sanghamita mbbs dgo md ficog
- Retired Professor and Head
- EDEN Hospital
- Professor
- Saraswathi Institute of Medical Science
- Ghaziabad, Uttar Pradesh, India
- Nalini Mahajan md m(art) ficog
- Director
- Mother and Child Hospital
- New Delhi, India
- Nandan Roongta dnb dgo dfp
- Consultant Gynecologist
- Bloom IVF Centre, Lilavati Hospital
- Mumbai, Maharashtra, India
- Nandita Palshetkar md fcps ficog
- Senior Vice President of FOGSI
- Clinical Secretary of Mumbai
- OBGYN Society
- Treasurer of Indian Association of Gynecological Endoscopy
- Member of the Managing Committee of ISAR
- Consultant IVF Expert at Fortis Bloom
- IVF Centre New Delhi/Mohali/Vashi and at Lilavati Hospital Mumbai
- Trustee DY Patil Medical College
- Mumbai and Group
- Mumbai, Maharashtra, India
- Narendra Malhotra md ficog ficmch
- Director
- Malhotra Nursing and Maternity
- Home (P) Ltd
- Agra, Uttar Pradesh, India
- Pallavi Pasricha md
- FNB Student
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Pankaj Talwar vsm
- Head of the Department
- Assisted Reproductive Technology Center
- Trained in Human Embryonic Stem Cell
- Biology (Israel)
- Trained in Onco-ART(France)
- Army Hospital (Research and Referral)
- New Delhi, India
- Partha Guha Roy md dgo
- Senior Clinical Consultant
- Fertility Clinic and IVF Centre
- Gamdevi, Mumbai, Maharashtra, India
- Parul Kotdawala md ficog
- Kotdawala Women's Clinic
- 53/1 BMM Society, Ellisbridge
- Ahmedabad, Gujarat, India
- PK Shah md ficog fcps ficmu ficmch dgo dfp
- Professor and Head
- Department of Obstetrics and Gynecolog
- KEM Hospital
- Mumbai, Maharashtra, India
- President, FOGSI 2012
- Pradip Kumar Mitra md
- Consultant and Gynecologist
- Kolkata, West Bengal, India
- Pragya Mishra Choudhary mrcog phd dffp micog
- Diplomate in Gyne-Endoscopy
- University of Kiel, Germany
- Consultant
- MGM Hospital and Research Centre
- Patna, Bihar, India
- Pramathes Das Mahapatra dgo md frcog frcs frcs
- Director
- Spectrum Clinic and Endoscopy Research Institute
- Chairman, AlCC, RCOG
- Pratap Kumar md dgo fics ficog
- Professor
- Department of Obstetrics and Gynecology
- Division of Reproductive Medicine
- Kasturba Medical College
- Manipal University
- Manipal, Karnataka, India
- Purbita Dam md fnb
- Assistant Professor
- Obstetrics and Gynecology
- Calcutta Medical College
- Kolkata, West Bengal, India
- Radhika L Kundula md
- FNB Student
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Rajeev Agarwal dgo md
- Director, CARE IVF
- Kolkata, West Bengal, India
- Ratna Chattopadhyay
- IVF Specialist
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Rishma Dhillon Pai md dnb dgo fcps ficog
- Past Senior Vice President FOGSI
- Treasurer of Indian Society of Assisted Reproduction
- Convenor DNB at Jaslok Hospital
- Member of the Managing Committee of Mumbai
- OBGYN Societies and IAGE
- Consultant IVF Expert at Fortis Bloom IVF Centre New Delhi/Mohali/Vashi and at Lilavati Hospital
- Mumbai, Maharashtra, India
- Sadhana K Desai md frcog
- Founder Director
- Fertility Clinic and IVF Centre
- Gamdevi, Mumbai, Maharashtra, India
- Past President, FOGSI
- Saktirupa Chakraborty mbbs dgo md
- Consultant Gynecologist
- Sanghamitra Ghosh
- IVF Specialist
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Satish Kumar Adiga
- Division of Reproductive Medicine
- Kasturba Medical College
- Manipal University
- Manipal, Karnataka, India
- Saumya N Gada bsc mba ma
- Counsellor
- Gada Life ART Centre
- CHL Apollo Hospitals
- Indore, Madhya Pradesh, India
- Shalu Gupta ms dnb fnb
- (Reproductive Medicine)
- Mother and Child Hospital
- New Delhi, India
- Shiuli Mukherjee md fnb
- Consultant (Reproductive Medicine)
- BIRTH, Kolkata, West Bengal, India
- Shivani Singh md dnb fnb
- (Reproductive Medicine)
- Mother and Child Hospital
- New Delhi, India
- Shyam PS
- Division of Reproductive Medicine
- Kasturba Medical College
- Manipal University
- Manipal, Karnataka, India
- Siddhartha Chatterjee dgo dnb frcog ficog
- Director and Chief Consultant
- Calcutta Fertility Mission
- Kolkata, West Bengal, India
- SK Goswami
- IVF Specialist
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Soma Singh md
- FNB Student
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Somajita Chakraborty mbbs dgo ms dnb mnams
- Associate Professor
- Department of Obstetrics and Gynecology
- Medical College
- Kolkata, West Bengal, India
- Sonal Kotdawala md
- Kotdawala Women's Clinic
- Ahmedabad, Gujarat, India
- Sujata Kar mbbs md dnb
- Consultant (Obstetrics and Gynecology)
- Kar Clinic and Hospital Pvt Ltd
- Bhubaneshwar, Orissa, India
- Sulekha Pandey dgo md
- Professor
- Department of Obstetrics and Gynecology
- Banaras Hindu University
- Varanasi, Uttar Pradesh, India
- Sunita Sharma md fnb
- Consultant
- Institute of Reproductive Medicine
- Kolkata, West Bengal, India
- Tarun Kumar Ghosh mbbs md
- Professor and Head
- Department of Obstetrics and Gynecology
- Institute of Postgraduate Medical
- Education and Research and Seth Sukhlal Karmani Memorial Hospital
- Kolkata, West Bengal, India
- Thankam R Varma frcog phd
- Medical Director
- Madras Medical Mission
- Chennai, Tamil Nadu, India
- Vasan SS dnb (Urology) fics
- Fellowship in Andrology
- Director, Department of Uroandrology
- Ankur Healthcare Pvt Ltd
- Bengaluru, Karnataka, India
- Director
- Manipal Andrology and Reproductive
- Services, Bengaluru, Karnataka, India
- Veena Acharya ms
- Professor and Unit Head
- Mahatma Gandhi Medical College and Hospital
- Jaipur, Rajasthan, India
- Ex-Superintendent, Mahila Chikitsalaya
- Vijay Ghorpade mbbs dgo ms
- Assistant Professor
- Department of Obstetrics and Gynecology
- KEM Hospital
- Mumbai, Maharashtra, India
The incidence of infertility has continued to rise over the last few decades and it is estimated that it affects at least 11% of couples of reproductive age. Many women are choosing to have children later in life, after they have established their careers and achieved financial security. Unfortunately, the biological time clock does not match these socioeconomic choices. Infertility is an emotionally traumatic life event. It can adversely affect the couple's or woman's emotional, spiritual, psychological and physical well-being.
Intrauterine insemination (IUI) is a common therapeutic modality in infertility. It is considered to be an intermediate step of low-to-moderate complexity, attempted before the application of more sophisticated assisted reproductive technologies like in vitro fertilization (IVF), with or without intracytoplasmic sperm injection (ICSI). It is very popular amongst gynecologists and performed regularly even at lower levels of care. Yet, the success rates of this simple procedure are often below expectations and disappointing. It is the sensitive area of uncertainty and unanswered questions that we have tried to explore. The book has brought together all the diverse aspects of IUI through the contribution by various authors who have been experts in this discipline for a long time.
However, a book written by many is naturally prone to have lack of continuity with non-uniformity in presentation and divergence of views. We have tried to prevent overlapping and break in continuity, with simultaneous stress on the widely-accepted concepts. The presentation has been made uniform as far as possible. We hope, the book can provide a clear and concise aspect of how, when, why and therefore of IUI and help you navigate the procedure smoothly and successfully.
The book is brought out under the aegis of RN Ganguly Foundation, Kolkata, West Bengal, India, which apart from engaging in social work, helping students, arranging free health check-ups and public awareness programs, also endeavorers towards academic excellence by organizing CMEs for doctors and publishing books. Genital Tuberculosis published in 2010 was the first medical book under this banner.
We express our deep appreciation and gratitude to all the contributors for their hard work, devotion and sincerity in writing the various chapters of the book. We thank M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, for their continuous support in making this book a reality.
We, earnestly hope, the book will be equally informative and useful to both practicing gynecologists and consultants as well as postgraduate students and benefit them in achieving better results in their day-to-day practice.
Gita Ganguly Mukherjee
BN Chakravarty