IAP Specialty Series on Rational Antimicrobial Practice in Pediatrics Nitin K Shah, Tanu Singhal
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1IAP Specialty Series On: Rational Antimicrobial Practice in Pediatrics2
3IAP Specialty Series On: Rational Antimicrobial Practice in Pediatrics
Second Edition
Founder Editor Dr Nitin K Shah Editors Dr Tanu Singhal Consultant Pediatrician and Infectious Disease Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute Mumbai, Maharashtra, India Dr Nitin K Shah Professor and Consultant Department of Pediatrics PD Hinduja Hospital and Medical Research Center Mumbai, Maharashtra, India Co-ordinating Editor Dr Sailesh Gupta Honorary Secretary General Indian Academy of Pediatrics Kailash Darshan, Kennedy Bridge Mumbai, Maharashtra, India Foreword Dr CP Bansal IAP President 2013 Dr Rohit Agrawal IAP President 2012
IAP National Publication House, Gwalior
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This book has been published in good faith that the contents provided by the contributors contained herein are original, and is intended for educational purposes only. While every effort is made to ensure accuracy of information, the publisher and the editors specifically disclaim any damage, liability, or loss incurred, directly or indirectly, from the use or application of any of the contents of this work. If not specifically stated, all figures and tables are courtesy of the editors. Where appropriate, the readers should consult with a specialist or contact the manufacturer of the drug or device.
Rational Antimicrobial Practice in Pediatrics
Second Edition: 2013
9789350903636
Printed at Ajanta Offset
5Contributors 9Foreword
Dear Reader,
The book that you hold is the fulfilment of the dreams of the doyens of Indian Academy of Pediatrics. For many years, the need for good Indian books in every specialty of pediatrics was felt. The Indian Academy of Pediatrics has no dearth of great teachers and writers in the various subspecialties to author these books. Their dedicated and diligent labor has created the beautiful and eminently readable book that you hold. An Indian book by Indian authors will appropriately suit the needs of the readers in India and in countries with similar geographical and sociocultural milieus. Although the first editions of the IAP subspecialty series were published in 2006, we proudly present to you a second, completely revised and updated edition.
The IAP specialty series books serve the purpose of providing evidence based, authentic and uniform information to IAP members, other pediatricians, and students of pediatrics in the country. Guidelines and established protocols on disease management will be very helpful for pediatricians in their everyday practice.
Creating a book is such as the birth of a baby. Right from conception to delivery, there is a long and complex process. It is very labor intensive, time-consuming work that involves considerable financial expense too. To streamline the entire process from writing to editing to publishing to distribution and sales of books, it was envisioned to have an additional wing of IAP, and which is established as “IAP National Publication House (IAP NPH)” at Gwalior.
Knowledge has no limits and seekers of knowledge can access the subject from anywhere in the world. We understand that books published by IAP NPH will be read and referred not only in India but also in many parts of the world. Objective of IAP NPH, therefore, is to provide standardized content and world class quality. With this objective, printed books are to be made available throughout the globe and distribution will also be done through online editions. Publishing 7 books at a time is a mammoth task and for this we collaborated with the second largest medical publisher in the world, i.e. M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India.
What you are reading, the world is also reading. Our writers are getting worldwide exposure and readers are getting world class books at reasonable cost.
It needs to be mentioned here that all authors and editors have dedicated the royalty from sale of books to IAP and have thereby done a selfless service for our mother organization. By buying this book, you are also contributing to IAP in a significant manner.
Finally, we express our pride and happiness in being associated with this project and in reaching this valuable book to you. We wish you a happy and contented reading.
Dr CP Bansal
IAP President 2013
Dr Rohit Agrawal
IAP President 2012
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11Preface
Antimicrobial therapy is an integral part of pediatric practice. If practised inappropriately, it can lead to treatment failure as well as antimicrobial resistance. Though several textbooks on similar issues are available, a need was felt to bring out a compendium that discusses these issues in light of Indian epidemiology. The first edition released in 2006 was very well received.
Antimicrobial therapy is a dynamic subject; there is evolution in antimicrobial resistance as well as new drugs are approved and marketed. Several such sentinel events have occurred in the past 6 years. Remarkable is the increase in community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections and the evolution and spread of carbapenem-resistant gram-negative bacteria. To address these and other changes in antimicrobial treatment options and guidelines, it was considered necessary to bring out a revised edition.
It gives us great pleasure in presenting the second edition of this book. We hope that this text is useful to practising pediatricians and postgraduates not only in India but also South Asia. If this book helps even a little bit in stemming the rise of the antimicrobial resistance monster, the efforts of the contributors and editors will be suitable rewarded.
Tanu Singhal
Nitin K Shah