Diagnostic Radiology: Recent Advances and Applied Physics in Imaging Niranjan Khandelwal, Veena Chowdhury, Arun Kumar Gupta, Sanjay Sharma, Ashu Seith Bhalla, Smriti Hari
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fm1DIAGNOSTIC RADIOLOGY Recent Advances and Applied Physics in Imagingfm2
fm3AIIMS-MAMC-PGI Imaging Series DIAGNOSTIC RADIOLOGY Recent Advances and Applied Physics in Imaging
Second Edition
Editors Arun Kumar Gupta MD MNAMS FAMS Professor and Head Department of Radio-diagnosis All India Institute of Medical Sciences (AIIMS), New Delhi, India Veena Chowdhury MD Director Professor and Head Department of Radio-diagnosis Maulana Azad Medical College (MAMC), New Delhi, India Niranjan Khandelwal MD Dip NBE FICR Professor and Head Department of Radio-diagnosis Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India Associate Editors Sanjay Sharma MD DNB FRCR Additional Professor Department of Radio-diagnosis All India Institute of Medical Sciences (AIIMS), New Delhi, India Ashu Seith Bhalla MD MNAMS Additional Professor Department of Radio-diagnosis All India Institute of Medical Sciences (AIIMS), New Delhi, India Smriti Hari MD Associate Professor Department of Radio-diagnosis All India Institute of Medical Sciences (AIIMS), New Delhi, India
fm4
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Diagnostic Radiology: Recent Advances and Applied Physics in Imaging
First Edition: 2000
Second Edition: 2013
9789350904978
Printed at
fm5Contributors
  • Ajay Gulati MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Ajay Kumar MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Akshay Kumar Saxena MD Dip NBE
  • Additional Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Alpana Manchanda MD
  • Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Anil Chauhan MBBS Board Certified in Radiology, USA
  • Fellow, Body imaging, Department of Radiology
  • University of Texas MD Anderson Cancer center, Houston, USA
  • Anil K Pandey PhD
  • Assistant Professor (Medical Physics)
  • Department of Nuclear Medicine
  • AIIMS, New Delhi, India
  • Anindita Sinha MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Anish Bhattacharya DNB DRM MNAMS
  • Additional Professor
  • Department of Nuclear medicine
  • PGIMER, Chandigarh, India
  • Anjali Prakash DMRD DNB MNAMS
  • Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Anju Garg MD
  • Director Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Anupam Lal MD
  • Associate Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Arun Deep Arora MD
  • Senior Research Associate
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Arun Kumar Gupta MD MNAMS FAMS
  • Professor and Head
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Ashu Seith Bhalla MD MNAMS
  • Additional Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Atin Kumar MD DNB MNAMS
  • Associate Professor
  • Department of Radio-diagnosis
  • (Trauma Centre Division)
  • AIIMS, New Delhi, India
  • BR Mittal MD DRM DNB FICNM FAMS
  • Professor and Head
  • Department of Nuclear Medicine
  • PGIMER, Chandigarh, India
  • Chandan Jyoti Das MD DNB MNAMS
  • Assistant Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Chandrashekhara SH MD DNB MNAMS
  • Assistant Professor
  • Department of Radio-diagnosis
  • (BRAIRCH Division)
  • AIIMS, New Delhi, India
  • Deep Narayan Srivastava MD MNAMS FAMS
  • Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Devasenathipathy Kandasamy MD DNB FRCR
  • Assistant Professor
  • Department of Radio-diagnosis
  • (BRAIRCH Division)
  • AIIMS, New Delhi, India
  • Gaurav Pradhan DMRD DNB
  • Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Jyoti Kumar MD DNB MNAMS
  • Associate Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Kushaljit Singh Sodhi MD MNAMS FICR
  • Associate Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Madhusudhan KS MD FRCR
  • Assistant Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Mandeep Kang MD
  • Additional Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Manisha Jana MD DNB FRCR
  • Assistant Professor
  • Department of Radio-diagnosis
  • (BRAIRCH Division)
  • AIIMS, New Delhi, India
  • Manphool Singhal MD DNB MNAMS
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Manavjit Singh Sandhu MD FICR
  • Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Mukesh Kumar Yadav MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Naveen Kalra MD
  • Additional Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Niranjan Khandelwal MD Dip NBE FICR
  • Professor and Head
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Pratik Kumar PhD Dip RP
  • Additional Professor
  • Medical Physics Unit (BRAIRCH)
  • AIIMS, New Delhi, India
  • fm6Rajat Jain MD
  • Senior Resident
  • Department of Radio-diagnosis
  • MAMC
  • New Delhi, India
  • Raju Sharma MD
  • Professor
  • Department of Radio-diagnosis
  • AIIMS
  • New Delhi, India
  • Rakesh Kumar MD PhD
  • Additional Professor
  • Department of Nuclear Medicine
  • AIIMS
  • New Delhi, India
  • Rashmi Dixit MD
  • Professor
  • Department of Radio-diagnosis
  • MAMC
  • New Delhi, India
  • Sameer Vyas MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER
  • Chandigarh, India
  • Sanjay Sharma MD DNB FRCR
  • Additional Professor
  • Department of Radio-diagnosis (RPC Division)
  • AIIMS, New Delhi, India
  • Sapna Singh MD DNB MNAMS
  • Associate Professor
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • SC Bansal MA MSc (Med Tech) PhD
  • Lecturer
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Shashi Bala Paul
  • Senior Scientist
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Shivanand Gamanagatti MD MNAMS
  • Associate Professor
  • Department of Radio-diagnosis
  • (Trauma Centre Division)
  • AIIMS, New Delhi, India
  • Smriti Hari MD
  • Associate Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Surabhi Vyas MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • AIIMS, New Delhi, India
  • Thulkar S MD
  • Additional Professor
  • Department of Radio-diagnosis (BRAIRCH)
  • AIIMS, New Delhi, India
  • Tulika Singh MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER
  • Chandigarh, India
  • Veena Chowdhury MD
  • Director Professor and Head
  • Department of Radio-diagnosis
  • MAMC, New Delhi, India
  • Veenu Singla MD
  • Assistant Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
  • Vivek Gupta MD DM (Neuroradiology)
  • Associate Professor
  • Department of Radio-diagnosis
  • PGIMER, Chandigarh, India
fm7Preface to the Second Edition
The First Edition of diagnostic radiology volume on Advances in Imaging Technology was published in the year 2000. During the second series, technical advances were dealt with under different organ systems, and no separate volume was compiled. The explosion of imaging technology in the last decade and the imperative need for the radiologist to stay abreast with these, motivate us to release a new volume on topic. The ever-evolving field of radiology makes continuing education in technical advances almost a compulsion rather than an option for those in the field. As a commitment to our readers and as part of our constant endeavor to improve as students ourselves, we publish the new edition titled Recent Advances and Applied Physics in Imaging.
Recent years have witnessed an astounding revolution in the field of imaging technology. At the heart of this revolution are major strides taken by the industry in all modalities including radiography, ultrasonography, digital subtraction angiography, computed tomography and magnetic resonance imaging. The imaging has moved from anatomic to functional, from static to real-time and from 2 dimensional to 3 or even 4 dimensional. All these major advancements in the information provided are expected at a faster rate and with lesser radiation dose. It is truly a tribute to science that several of these goals have actually been achieved. As radiologists, we have been privileged to be the chosen few to deliver these stunning images to the medical community. With this, however, comes greater responsibility. Our ability to create and interpret these amazing pictures requires us to comprehend the physics that goes into creating them. Also, the onus of minimizing the cost of imaging, selection of the optimal modality and minimizing radiation exposure finally rests on us.
This book has hence been planned as a volume attempting to summarize and deliver the advances in imaging technology relevant to the radiologist in a manageable capsule. We hope that it will serve as your friend and companion in understanding and negotiating the labyrinth of Imaging Physics. Compared to the First Edition published in 2000, the book has understandably been majorly restructured. We have attempted to cover all major aspects of technological advances relevant to a practicing radiologist, while keeping the book compact. It is our earnest hope that our readers will find this text informative and that it will aid in their learning process and daily practice.
We wish to thank all the contributors from the institutions, i.e. All India Institute of Medical Sciences, New Delhi, Maulana Azad Medical College, New Delhi and Postgraduate Institute of Medical Education and Research, Chandigarh, India, for their efforts in compiling this edition. We would also like to express our sincere appreciation to Shri Jitendar P Vij (Group Chairman), Mr Ankit Vij (Managing Director), Mr Tarun Duneja (Director-Publishing), Mrs Samina Khan (PA to Director-Publishing), Mr KK Raman (Production Manager), Mr Sunil Kumar Dogra (Production Executive), Mr Neelambar Pant (Production Coordinator), Mr Subrata Adhikary (Commissioning Editor), Dr Mohd Naved (Senior Proofreader), Mr Girish Pandey (Typesetter), Mr Dinesh Joshi (Graphic Designer) and other staff of M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, for their professionalism and dedication towards publication of this edition.
Arun Kumar Gupta
Veena Chowdhury
Niranjan Khandelwalfm8
fm9Preface to the First Edition
Diagnostic imaging has undergone an astonishingly rapid transformation over the last two decades. The constant expansion of imaging techniques and their potential is based on scientific and technical advances including improvement in computer hardware and software technology. The fusion of computer technology to diagnostics imaging was indeed a turning point in the history of diagnostics imaging. This, in fact, has brought medical imaging to the forefront of various clinical disciplines.
The amazing speed at which the field of radiology is mushrooming today would have surely astounded Roentgen, the “Father” of radiology. While physicians, a century ago, struggled with the nation of looking inside the living body without the cutting it open. At present, the physicians find it almost impossible to practice medicine without the help of sophisticated diagnostics imaging.
Cross-sectional imaging modalities have revolutionized the concept of imaging. Ultrasonography has advanced into wider areas of applications with increasing contrast use of color Doppler and Power Doppler techniques. The introduction of ultrasound contrast media and tissue harmonic imaging has further opened up new vistas in clinical applications of ultrasonography.
Since its introduction in 1971, computed tomography (CT) technology has come a long way. Modern scanners, capable of subsecond scanning, are ideal for the scanning chest and abdomen in a single breath-hold. Additional improvement includes more detectors to increase resolution and finer collimation allowing a reduction in slice thickness to minimize partial volume averaging. Introduction of spiral scanners has widened the scope of imaging by making 3D CT and 3D CT angiography possible.
Magnetic resonance imaging (MRI) was introduced into clinical medicine in 1981 and within a short time, it has assumed a role of unparalleled importance in diagnostic medicine. It is probably the most important imaging advancement since the introduction of X-rays in 1895. The resolution of 3D MR and 3D MR angiography has also advanced to the stage, where the replacement of conventional invasive angiography is now in sight. However, MR spectroscopy has failed to fill its early promise and still await routine clinical acceptance.
The role of the radiology is fast changing from that of a diagnostician usually supporting clinical diagnosis to that of a more active colleague tackling various clinical problems and performing a wide gamut of interventional procedures. The interventional radiologist of today is indeed going to be surgeon of the new millennium.
Functional neuroimaging with PET and SPET is emerging from the research stages and when more freely available, may have a major influence on clinical practice.
Teleradiology, which allows long distance transmission of images by extensive networking, has expanded the scope of diagnostic imaging well beyond our expectation.
The student of radiology needs constant guidance through this bewildering plethora of new information on imaging technology. A comprehensive understanding of technological advances in imaging and their clinical applications are necessary for practicing radiologists to be able to make an optimal choice of investigation in helping the referring physician to reach at a diagnosis.
Keeping this in mind, the faculty of radio-diagnosis at the All India Institute of Medical Sciences, Maulana Azad Medical College, New Delhi and Postgraduate Institute of Medical Education and Research, Chandigarh, India, present this seventh book in the series of Diagnostic Radiology, devoted to Advances in Imaging Technology, thus concluding the series of AIIMS, MAMC, PGI Imaging Courses.
fm10This book comprises of 16 chapters, covering the recent advances in ultrasonography, computed tomography, magnetic resonance imaging, nuclear medicine, digital radiography and interventional radiology. In addition, a full chapter has been devoted to the role of Internet in Radiology. Also, this book includes 7 more chapters on the subjects, which could not be covered in earlier volumes.
We hope, the reader shall find this book informative and valuable for better use of imaging technology.
We wish to take this opportunity to thank our faculty colleagues from AIIMS, MAMC and PGIMER for their active support and cooperation. We also express our sincere thanks to Shri Jitendar P Vij (Group Chairman) and other staff of M/s Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, India, for timely publication of all previous books including the present one.
Manorama Berry
Veena Chowdhury
Sudha Suri
Sima Mukhopadhyayfm11fm12fm13fm14