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Atlas of Gynecologic Cytology
Ossama Tawfik, Marilee Means
CHAPTER 1:
The State of the Pap Test: A Historical Perspective, from Past to Present
CHAPTER 2:
The Future of the Pap Test: Digitization and Cytology
DIGITAL CYTOPATHOLOGY AND TELECYTOLOGY
Advantages of Telepathology
Digital Cytopathology/Telecytology: Are we there yet?
CHAPTER 3:
The TelePAPology™ Solution
WHAT IS TELEPAPOLOGY™?
Methodology
Cellblocks as a Replacement or Adjunct for Routine or Liquid-based Pap Tests
MOTIVATION FOR TELEPAPOLOGY™
Advantages of TelePAPology™
CHAPTER 4:
TelePAPology™ and the Bethesda Reporting System
NORMAL ANATOMY AND HISTOLOGY
THE BETHESDA REPORTING SYSTEM
TELEPAPOLOGY™ AND THE BETHESDA REPORTING SYSTEM
CHAPTER 5:
Specimen Adequacy, Infections and Other Benign Changes
SPECIMEN ADEQUACY
SQUAMOUS CELLS
GLANDULAR CELLS
BENIGN CELLULAR CHANGES
Squamous Metaplasia
KERATOSIS
Reparative/Regenerative and Inflammatory Changes
The value of CB-prepared TelePAPology™ Samples
ORGANISMS AND INFECTIONS
Shift in Flora Suggestive of Bacterial Vaginosis (BV)
Fungal Organisms Morphologically Consistent with Candida Species
Trichomonas Vaginalis
Herpes Simplex
Cytomegalovirus (CMV)
CHAPTER 6:
Epithelial Abnormalities: Squamous Cells
SQUAMOUS CELL LESIONS OF THE UTERINE CERVIX
Atypical Squamous Cells of Undetermined Significance (ASCUS)
Low Grade Squamous Intraepithelial Lesion (LSIL)
High Grade Squamous Intraepithelial Lesion (HSIL)
SQUAMOUS CELL CARCINOMA
Keratinizing Type
Non-keratinizing Type
CHAPTER 7:
Epithelial Abnormalities: Glandular
GLANDULAR LESIONS OF THE UTERINE CERVIX
ATYPICAL GLANDULAR CELLS OF UNDETERMINED SIGNIFICANCE (AGUS)
ENDOCERVICAL ADENOCARCINOMA IN SITU
INVASIVE ENDOCERVICAL ADENOCARCINOMA
ENDOMETRIAL ADENOCARCINOMA
RARE LESIONS AND METASTATIC TUMORS TO THE UTERUS
CHAPTER 8:
Ancillary Testing and Image Analysis
HUMAN PAPILLOMAVIRUS TESTING
DIAGNOSTIC UTILITY OF TELEPAPOLOGY™ AND IMMUNOHISTOCHEMISTRY
p16, MIB-1 and ProExTM C Immunohistochemistry
EVALUATION OF ATYPICAL GLANDULAR CELLS
Evaluation of Adenocarcinomas (Endocervical vs Endometrial vs Metastatic) and Other Malignancies
UTILIZATION OF CELLBLOCKS PROVIDES AN ADDED VALUE OF PERFORMING ADDITIONAL ANCILLARY TESTS FOR INFECTIOUS DISEASES
IMAGE ANALYSIS
The Value of Computer-Aided Image-Based Scoring Algorithms Suitable for a Remote, Web-Based (GPS guided) Analysis of Cellblock Preparations from Pap Samples
Performance
Software
Feature Extraction
Learning and Classification
INDEX
TOC
Index
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