Academic Editor Suraj Gupte
Executive Editors Shamma-Bakshi Gupte
Manu Gupte
- Recent Advances in Pediatrics (RAP): Hot Topics (General/Miscellaneous Pediatrics)Vol 21 (2013), Vol 20 (2011), Vol 19 (2010), Vol 18 (2009), Vol 17 (2007), Vol 16 (2006), Vol 15 (2005), Vol 14 (2004), Vol 13 (2003), Vol 12 (2002), Vol 11 (2001), Vol 10 (2000), Vol 9 (1999), Vol 8 (1998), Vol 7 (1997), Vol 6 (1996), Vol 5 (1995), Vol 4 (1994), Vol 3 (1993), Vol 2 (1992), Vol 1 (1991)
- Recent Advances in Pediatrics (RAP): Special VolumesRAP Special Vol 25: Perspectives in NeonatologyRAP Special Vol 24: Respiratory DiseasesRAP Special Vol 23: Pediatric Gastroenterology, Hepatology and NutritionRAP Special Vol 22: Immunology, Infections and ImmunizationRAP Special Vol 21: Neonatal and Pediatric Intensive CareRAP Special Vol 20: Nutrition, Growth and DevelopmentRAP Special Vol 19: Developmental and Behavioral PediatricsRAP Special Vol 18: Pediatric NeurologyRAP Special Vol 17: AdolescenceRAP Special Vol 16: Pediatric CardiologyRAP Special Vol 15: NephrologyRAP Special Vol 14: Critical Care PediatricsRAP Special Vol 13: Pediatric EndocrinologyRAP Special Vol 12: Neonatal EmergenciesRAP Special Vol 11: Community PediatricsRAP Special Vol 10: PulmonologyRAP Special Vol 09: NeurologyRAP Special Vol 08: Emergency PediatricsRAP Special Vol 07: HematologyRAP Special Vol 06: Gastroenterology, Hepatology and NutritionRAP Special Vol 05: Neonatology – 2RAP Special Vol 04: NeonatologyRAP Special Vol 03: Tropical Pediatrics – 2RAP Special Vol 02: Tropical PediatricsRAP Special Vol 01: Nutrition, Growth and Development
- Recent Advances in Pediatrics (RAP) Volumes in Pipeline
- RAP 23: Hot Topics (General/Miscellaneous Pediatrics)
- RAP Special Vol 26: Infectious Diseases
Other Books by Prof (Dr) Suraj Gupte
- The Short Textbook of Pediatrics, 12th edition, 2014
- Differential Diagnosis in Pediatrics, 5th edition, 2009
- Instructive Case Studies in Pediatrics, 5th edition, 2011
- Pediatric Drug Directory, 8th edition, 2014.
Honorary Director: Pediatric Education Network
Editor: The Short Textbook of Pediatrics; Textbooks of Pediatric Emergencies, Neonatal Emergencies, Pediatric Nutrition, and Pediatric Gastroenterology, Hepatology and Nutrition, Pediatric Infectious Diseases, Influenza: Complete Spectrum, Towards MRCPCH Part II (Theory) Examination, Pediatric Yearbook (Series), Newer Horizons in Tropical Pediatrics, etc.
Author: Differential Diagnosis in Pediatrics, Instructive Case Studies in Pediatrics, Influenza, Perspectives in Influenza, Pediatric Drug Directory, Infant Feeding, Speaking of Child Care, The Baby Book: The Parents’ Guide from Birth to Infancy
Co-editor: Asian Journal of Maternity and Child Health (Manila, Philippines)
Section and Guest Editor: Pediatrics Today (New Delhi)
Editorial Advisor: Asian Journal of Pediatrics Practice (New Delhi)
Editorial Advisory Board Member/Reviewer: Indian Journal of Pediatrics (New Delhi), Indian Pediatrics (New Delhi), Synopsis (Detroit, USA), Indian Journal of Pediatric Gastroenterology, Hepatology and Nutrition (Jaipur), Maternal and Child Nutrition (Preston, UK), Journal of Pediatric Infectious Diseases (Turkey)
Examiner: National Board of Examinations (NBE) for DNB, New Delhi; All India Institute of Medical Sciences (AIIMS), New Delhi; Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh; Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar; Indira Gandhi National Open University (IGNOU), New Delhi, India
Pediatric Faculty Selection Expert: All India Institute of Medical Sciences (AIIMS), Punjab Public Service Commission, Jammu and Kashmir Public Service Commission, Union Public Service Commission, etc.
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© 2014, Shamma-Bakshi Gupte/Manu Gupte (Executive Editors)
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Recent Advances in Pediatrics—22: Hot Topics
First Edition: 2014
9789351521563
Printed at
FM5Dedicated to
My dear Parents
whose inspiration, motivation, blessings
and moral support continue to contribute a great
deal to our academic endeavors
and
everybody striving to contribute to child health
and welfare for a brighter future globally
FM7CONTRIBUTORS
- Shahida Afroz
- Assistant Professor in Hepatology
- Institute of Child and Adolescent Health
- London, United Kingdom
- Harmesh S Bains
- Professor and Head
- Department of Pediatrics
- Dayanand Medical College (DMC)
- Ludhiana, Punjab, India
- Anil Bajaj
- Assistant Professor
- Department of Pediatrics
- Medical College
- Amravati, Maharashtra, India
- Vasant Chinnabhandar
- Department of Pediatric Hematology
- Oncology and Bone Marrow Transplantation
- Institute of Child Health
- Sir Ganga Ram Hospital
- New Delhi, India
- Anjul Dayal
- Consultant Pediatric Intensivist
- Continental Children's Center
- Continental Hospitals
- Hyderabad, Andhra Pradesh, India
- Hitesh Dhawan
- Senior Resident
- Department of Pediatrics
- Dayanand Medical College (DMC)
- Ludhiana, Punjab, India
- KE Elizabeth
- Consultant Nutritionist and Geneticist
- Professor in Pediatrics
- Medical College and SAT Hospital
- Trivandrum, Kerala, India
- Gloria Evert
- Professor Emeritus
- (Infectious Diseases)
- University of Michigan
- Michigan, USA
- Deepak Goyal
- Associate Consultant
- Department of Pediatric
- Gastroenterology, Hepatology and Liver Transplantation
- Medanta–The Medicity Hospital
- Gurgaon, NCR, India
- Anil Grover
- Professor and Head
- Department of Cardiology
- Mamata Medical College/Mamata General and Superspecialty Hospitals
- Khammam, Andhra Pradesh, India
- Novy Gupte
- Drug Safety Physician
- APCER Pharma India Limited
- New Delhi, India
- Suraj Gupte
- Professor and Head
- Postgraduate Department of Pediatrics
- Mamata Medical College/Mamata General and Superspecialty Hospitals
- Khammam, Andhra Pradesh, India
- Sandhya Gupta
- Assistant Professor
- Department of Physiology
- Institute of Medical Sciences and SUM Hospital
- Bhubaneshwar
- Odisha, India
- Aditya Kumar Gupta
- Department of Pediatric Hematology,
- Oncology and Bone Marrow Transplantation
- Institute of Child Health
- Sir Ganga Ram Hospital
- New Delhi, India
- Gagan Hans
- Senior Resident
- Department of Psychiatry
- Lady Hardinge Medical College
- New Delhi, India
- Shripad Jahagirdar
- Assistant Professor
- Department of Pediatrics
- Medical College
- Amravati, Maharashtra, India
- Lalitha Kailas
- Professor and Head
- Department of Pediatrics
- Government Medical College and SAT Hospital
- Thiruvananthapuram (Trivandrum), Kerala, India
- Pratibha Kale
- Associate Professor
- Department of Pediatrics
- Medical College
- Amravati, Maharashtra, India
- Madhuri Kanitkar
- Pediatric Nephrologist
- Deputy Director General
- (Planning and Training)
- Armed Forces Medical Services
- New Delhi, India
- Sakshi Karkra
- Associate Consultant
- Department of Pediatric
- Gastroenterology, Hepatology and Liver Transplantation
- Medanta-The Medicity Hospital
- Gurgaon, NCR, India
- BP Karunakara
- Professor and Intensivist
- Department of Pediatrics
- MS Ramaiah Medical College and Medical Teaching Hospital
- Bengaluru (Bangalore), Karnataka, India
- Gibby Koshy
- Post-doctoral Research Assistant
- Malaria in Pregnancy Consortium and Epidemiology Unit
- WHO Collaborating Centre for Prevention of Deafness
- Child and Reproductive Health Group
- Department of Clinical Sciences and International Public Health
- Liverpool School of Tropical Medicine
- University of Liverpool
- Liverpool, United Kingdom
- Vinod Kumar
- Associate Professor
- Department of Cardiology
- Mamata Medical College/Mamata General and Superspecialty Hospitals
- Khammam, Andhra Pradesh, India
- Anil Kumar
- Associate Professor
- Department of Pediatrics
- Government Medical College
- Nellore, Andhra Pradesh, India
- Sudhir Mishra
- Senior Specialist in Pediatrics Incharge PICU
- Associate Professor (Hon) in Pediatrics
- MGM Medical College
- Jamshedpur, Jharkhand, India
- Neelam Mohan
- Senior Consultant and Director
- Department of Pediatric
- Gastroenterology, Hepatology and Liver Transplantation
- Medanta-The Medicity Hospital
- Gurgaon, NCR, India
- Manjunath Mallikarjuna Nagalli
- Associate Professor
- Department of Pediatrics
- MS Ramaiah Medical College and Medical Teaching Hospital
- Bengaluru (Bangalore), Karnataka, India
- Ranjith Nair
- Senior Adviser
- (Medicine and Nephrology)
- Military Hospital
- Jullundur, Punjab, India
- Gouri Rao Passi
- Consultant
- Department of Pediatrics
- Choithram Hospital and Research Center
- Indore, Madhya Pradesh, India
- Rachana Pole
- Resident Doctor
- Civil Hospital
- Ahmedabad, Gujarat, India
- Fatima Quereshi
- Research Scholar
- Clinical Pharmacology
- Institute of Child and Adolescent Health
- London, United Kingdom
- R Praveen
- Pediatrician
- 92 Base Hospital
- C/O 56 APO
- Nita Radhakrishnan
- Department of Pediatric Hematology,
- Oncology and Bone Marrow Transplantation
- Institute of Child Health
- Sir Ganga Ram Hospital
- New Delhi, India
- Uma Raju
- Senior Consultant and Professor
- Pediatrics and Neonatology
- INHS Asvini
- Mumbai, Maharashtra, India
- Ramani Ranjan
- Registrar
- Department of Pediatrics
- Tata Main Hospital
- Jamshedpur, Jharkhand, India
- E Venkata Rao
- Associate Professor
- Department of Community Medicine
- Institute of Medical Sciences and SUM Hospital
- Bhubaneshwar, Odisha, India
- L Ranbir Singh
- Professor and Head
- Department of Pediatrics
- Regional Institute of Medical Sciences (RIMS)
- Imphal, Manipur, India
- Anupam Sachdeva
- Director
- Department of Pediatric Hematology,
- Oncology and Bone Marrow Transplantation
- Institute of Child Health
- Sir Ganga Ram Hospital
- New Delhi, India
- Sangeetha Shenoy
- Associate Professor
- Department of Pediatrics
- MS Ramaiah Medical College and Teaching Hospital
- Bengaluru (Bangalore), Karnataka, India
- Ahmar Shamim
- Fellow
- Department of Pediatric
- Gastroenterology, Hepatology and Liver Transplantation
- Medanta-The Medicity Hospital
- Gurgaon, NCR, India
- Daljit Singh
- Senior Advisor (Pediatrics)
- Air Force Hospital
- Kanpur, Uttar Pradesh, India
- Utpal Kant Singh
- Professor and Head
- Department of Pediatrics
- Nalanda Medical College
- Patna, Bihar, India
- K Srikanth
- Consultant Neonatologist
- Continental Children's Center
- Continental Hospitals
- Hyderabad, Andhra Pradesh, India
- Satish Tiwari
- Professor
- Department of Pediatrics
- Medical College
- Amravati, Maharashtra, India
- Namratha Upadhya
- Assistant Professor
- Department of Pediatrics
- MS Ramaiah Medical College
- Bengaluru (Bangalore), Karnataka, India
- GK Vankar
- Professor and Head
- Department of Psychiatry
- BJ Medical College and Civil Hospital
- Ahmedabad, Gujarat, India
- Sarita P Verma
- Resident
- Department of Pediatrics
- Choithram Hospital and Research Center
- Indore, Madhya Pradesh, India
- Rajesh Vijayvergiya
- Associate Professor
- Advanced Cardiac Center
- Postgraduate Institute of Medical Education and Research (PGIMER)
- Chandigarh, India
Complimentary editorial comments on our last volume (RAP—21: Hot Topics) by the Asian Health have not just delighted the RAP fraternity but also lent further support to our resolve to present the best to our readers on topical pediatric issues with special accent on resource-limited regions.
The present volume (RAP—22: Hot Topics) presents 31 peer-reviewed state-of-the-art chapters contributed by as many as 48 experts drawn from India and abroad. The evidence-based chapters attempt to present the depth and breadth of knowledge in the field of contemporary pediatrics with special reference to its applicability in the Indian subcontinent and rest of the South-East Asian Region (SEAR).
A multitude of topical issues ranging from dengue fever, malaria, tuberculosis, influenza, primary immunodeficiency, cerebral palsy, ketogenic diet, celiac disease, hepatitis B, hepatocyte transplantation and nonalcoholic fatty liver and steatohepatitis through obesity, severe acute malnutrition (SAM), acute kidney injury and nephritic syndrome to rheumatic fever, congenital heart disease, sickle-cell disease, and thalassemia syndromes are dealt with.
Also incorporated are chapters on India's national child health programs, new neonatal resuscitative guidelines, dermatologic emergencies, status epilepticus and intracranial hypertension, sleep disorders and eating disorders. Chapters on adverse drug reactions, probiotics and newer antibiotics for vancomycin-resistant Staphylococcus aureus and other pathogens should be of special interest in the wake of evolving campaign for pharmacovigilance and rational drug therapy as also facing the problem of increasing antimicrobial resistance head-on.
In conformity with the policy of the RAP series ever since its inception and first appearance in 1991, each and every chapter is outstanding by its excellence, providing a stimulating, mature, informed, state-of-the-art and, at times, even provocative update. Such an approach is known to be befitting when the goal is not only to inform but also to motivate discussion, interaction, research and innovation. Multidisciplinary approach with an eye on future, a well-tested and well-appreciated conviction with the RAP series, continues to occupy pride of place in the present volume too.
All said and done, a galaxy of chapters focusing on the contemporary concepts, concerns, and controversies with emphasis on new and evolving concepts in child health as relevant in India and other South-East Asian countries forms the lifeline of the volume.
Here's wishing you all, dear readers, an enjoyable, fruitful and productive reading.
Suraj Gupte
Shamma-Bakshi Gupte
Manu Gupte
FM15ACKNOWLEDGMENTS
Grateful acknowledgments are made to:
- The distinguished contributors, both from India and abroad, for providing excellent state-of-the-art chapters on various topical issues in neonatology. They were gracious enough to repose confidence in our editorship.
- The peer-reviewers, for critically reviewing the contributions, thereby providing us the benefit of their expertise.
- The Advisory Editorial Board for providing inputs and advice in various editorial matters.
- The Management (Mamata Education Society), especially Mr P Ajay Kumar, Chairman; Mr K Sreedhar, Director; and Dr K Koteshwer Rao, Dean and Principal, Mamata Medical College and Hospitals, for blessing this project.
- Dr Gagan Hans and Dr Novy Gupte, for voluntarily helping us in various ways in taking the project to its logical conclusion over and above their own contributions.
- Various periodicals and journals for editorial and critical reviews.
- M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, and their dedicated staff for the skillful and admirable production qualities of the book.