Atopic Dermatitis and Pruritus: Interesting Cases Kiran Godse, Anant Patil
INDEX
Page numbers followed by b refer to box, f refer to figure, and t to table.
A
Abrocitinib 60
Achyranthes aspera 80
Acitretin 124
Allergens 4
penetration of 55
Allergic contact dermatitis 20, 40, 41, 55, 63, 69, 70
diagnosis of 40
Allergic diseases 16
Allium cepa 80
Allium sativum 80
Aloe vera 80
Antibiotics, systemic 98
Antifungals
systemic 110
topical 110
Antihistamine 106
Antineutrophil cytoplasmic antibody 94
Antinuclear antibody 94
Anxiety 15, 86
Arterial hypertension, systemic 11
Arthropod bites 120
Aspirin 89
Asthma 79
childhood-onset 62
personal history of 22
severe 62
Atopic dermatitis 1, 3, 6, 8, 8f, 9, 10, 15, 19, 21, 22b, 25, 27, 29, 30, 33, 35, 36, 38, 40, 41, 48, 51-53, 55, 57, 60t, 62, 63, 65, 65f, 66, 66f, 67, 70, 74, 76-79, 86, 87, 117, 120, 124
adult-onset 62, 63
classic early onset 32
erythrodermic early onset 32
pathogenesis of 55
refractory 29
severe 72
reliable estimation of 22
severe 3, 27, 52, 65
adult-onset 19
refractory 72
Atopic disease 11, 22
Atopy 79
family history of 22
personal history of 22
Autoimmune blistering disease 119
Azadirachta indica 80, 81
Azathioprine 13, 17, 29, 53, 65, 74, 85, 124
B
Baricitinib 60
Bauhinia variegata 80
Benralizumab 108, 108f, 109, 109f, 109t, 110
Biliary cholangitis, primary 15
Bladder, metastatic transitional cell carcinoma of 15
Blepharitis 67
Blepharoconjunctivitis, recurrent herpetic 65f
Boric acid compresses 5
Brachioradial pruritus 15
Bullous pemphigoid 45
Burns 58
C
Calcineurin inhibitors, topical 29, 62
Calcitonin gene-related peptide 15
Carbamazepine 48
Cataracts, anterior subcapsular 22
Celiac disease 15, 119
Cheilitis 22
Chikungunya infections, 14
Cholesterol ointment 5
Chronic autoimmune cholestatic hepatitis 15
Chronic inflammatory
disease 33
disorder 6
Chronic obstructive pulmonary disease 20
Clostridium difficile 5
Collagen fibers 15
Colophony 40, 41
Complete blood count 59, 62
Conjunctivitis 21, 30, 67, 70
allergic 22
recurrent 22
Contact allergy 38
Contact dermatitis 41, 117
Contrail sign 123
Coronavirus disease 17
Corticosteroid
systemic 65, 98
topical 29, 62, 69
COVID-19 17
C-reactive protein 20, 59, 62, 114
Cross-reactive carbohydrate determinant 5
Cutaneous lesions, evolution of 12f
Cutaneous pruriginous recurrent lesions 98
Cutaneous T-cell lymphoma 15, 21, 63
Cyclosporine 17, 29, 35, 37, 53, 65, 74, 85, 106, 110
D
Dapsone, systemic 110
Darier's disease 67
Darier–White disease 58
Delgocitinib 60
Delta glider sign 123
Demodex-associated rosacea-like dermatitis 70
Dendritic cells 15
Dengue 14
Dennie–Morgan infraorbital fold 22
Depression 15, 86
Dermal fibrosis 12
Dermal perivascular lymphocytic infiltrate 85
Dermatitis 22, 33, 55, 69
herpetiformis 117, 119, 120
Dermatology life quality index 25, 26, 29, 33, 52, 69, 72, 86, 126
Dermatome 15
Dermatosis, benign 77
Dermographism 113
diagnosis of 112
Dermoscopic clues 114
Dermoscopic examination 122f
Dermoscopy 123
Diabetes mellitus 15, 20, 79
DiGeorge syndrome 48, 49
Doxycycline 96
Drug reaction with eosinophilia and systemic symptoms syndrome 48
Dry eye 67
Dry skin 10
Duhring–Brocq disease 119
Dupilumab 11, 16, 19, 25, 30, 33, 34, 53, 63, 65, 67, 71, 124, 127, 127t, 128
therapy 14, 69
Dupilumab-induced face dermatitis 62
Dyslipidemia 89
Dystrophic epidermolysis bullosa 45
E
Eczema 104
area and severity index 17, 26, 33, 52, 69, 86
score 25, 32
herpeticum 57, 58, 65, 67
skin lesions of 58f
Electroencephalogram 48
Emollients 5
Encephalitis 59
Endothelial cells 15
Eosinophil 104
cationic protein 15, 109t
Eosinophilia 22, 109t
Eosinophilic folliculitis 108
pathogenesis of 110
Eosinophilic perifolliculitis 107
Epidermal keratinocytes 15
Epidermolysis bullosa pruriginosa 44, 45
skin lesions 45f
Erythematous papules 95, 112, 113f, 114, 121f
Erythematous patches 39f
Erythematous-desquamative mild infiltrated plaques 12f
Erythrocyte sedimentation rate 20, 59, 72, 94
Erythroderma 34
Extensor eruptions 22
Extractable nuclear antibody 94
Extracutaneous nerves 15
Eye pruritus 67
F
Facial eruptions 22
Facial pallor 22
Fast recurrent dermatitis 41
Fever 59
Filaggrin 73
Fitzpatrick's skin 11
Flexural involvement, history of 22
Flexural lichenification 22
Food
allergens 4t
allergy 35-37
intolerance 22
Foot dermatitis 22
Full blood count 114
Fungal skin infection 9
Fungal vellus hair 9f
Fungoides 32
G
Gabapentin 17, 124
Gamma benzene hexachloride 91
Generalized dry skin, history of 22
Generalized purpuric macules 89
Gilbert syndrome 57
Global Initiative for Asthma Guidelines 62
Gout 15
Gusacitinib 60
H
Hailey–Hailey disease 58
Hand dermatitis 22
refractory 41
Hand eczema, worsening of 40
Hanifin and Rajka diagnostic criteria 22
Hay fever 22
Headache 70
Heart disease, ischemic 79
Hepatitis
B 94
chronic 15
C 15, 94
Herpes infections 70
Herpes simplex viruses 58, 67
Histamine 15
HIV infection 15
Hodgkin lymphoma 15
Hospital anxiety and depression scale 86
Hydrochlorothiazide 89
Hypereosinophilia 107
Hypergranulosis 85
Hyperkeratosis 85
Hyperkeratotic epidermis 12
Hyperkeratotic plaques 39f, 40
Hyperpigmentation 96
Hypertension 79, 89
Hypopigmented polymorphous light eruption 77
I
Ichthyosis 22, 67
vulgaris 58
Immediate skin test reaction 22
Immunoglobulin E 26, 29, 66, 85, 112, 114
specific 5
Immunomodulators, topical 69
Impaired cell-mediated immunity 22
Incipient bullous pemphigoid 15
Inflammatory skin disease 127
Influenza 36
Injection site reactions 70
Intense xerosis 15
Intensive pruritus 117
Internal malignancies 15
International Alliance for Control of Scabies Criteria 91
Iron-deficiency anemia 15
Irregular acanthosis 12
Itching 22, 38, 89
Itchy rash 124
Itchy red raised lesions 121
Itchy skin condition 22
Itchy small papules 104, 105f
Itchy urticarial lesions 93
J
Janus family protein kinases 16
Janus kinase 27
inhibitors 57, 60, 60t
Juvenile eosinophilic folliculitis 107, 110
primary 110
treatment of 110
K
Kang and Tian diagnostic criteria 22
Kaposi varicelliform eruption 58
Keratitis 67
Keratoconus 22
Keratosis pilaris 22
Keto rash 96
Kidney
failure, chronic 15
function 48
L
Lactate dehydrogenase 26
Leukocytoclastic vasculitis 90f, 91
Lichen planus 15
Lichenoid papules 45f
Liver
diseases 15
function tests 48
Localized prurigo nodularis 15
Loratadine 98
Low-potent topical corticosteroid 78
Lymphadenopathy 59
Lymphocytes 104
Lymphocytic infiltration 96
M
Macrolides 110
Malaise 59
Malassezia furfur-associated dermatitis 70
Manidipine 89
Mast cells 15
Measles 36
Merkel cells 15
Methotrexate 17, 29, 53, 65, 74
Microsporum canis 10
Minitriangle sign 123
Minocycline 96
Mometasone furoate 5
Monoclonal gammopathy 15
Monoclonal T-cell receptor 32
Montelukast 106
Multiple drug allergies 51
Multiple eosinophilic granulocytes 108f
Multiple organ involvement 59
Mumps 36
Mycophenolate 53
mofetil 13, 17
Mycosis fungoides 21, 58, 63, 67, 77
N
Nagashima disease 96
Nasal fluticasone 53
Nasopharyngitis 70
Nerve
cutaneous 15
growth factor 15
Neuropathic diseases 15
Neuropathic pruritus 15
Neutrophils 104
Nevus depigmentosus 77
Nipple eczema 22
Nodules 85
Non-Hodgkin's lymphoma 15
Noninfectious pruritic dermatosis 108
Numerical rating scale 33, 86
Numerous keratinocytes, necrosis of 96
O
Obstructive sleep apnea 20
Omalizumab 44, 46, 72, 74
Oral corticosteroids 62, 69
Oral dapsone 96
Oral fluconazole 9
Oral hydroxyzine 98
Oral immunosuppressants 69
Oral valacyclovir 66
P
Palmar hyperlinearity 22
Papules 98
Papulopustular dermatosis 107
Paradoxical erythema 71
Parakeratosis foci 12
Paraphenylenediamine 40, 41, 41f
Patch test 29, 41, 56, 69, 85
reactions 41f
Patchy scaling erythema 70f
Patient-oriented eczema measure 86
Pemphigus
foliaceus 58
vulgaris 67
Periorbital darkening 22
Photophobia 65
Photosensitivity reaction, drug-induced 63
Phototherapy 17
Physician global assessment 33, 126
Pimecrolimus 52, 53
Pityriasis 77
alba 22, 77
lesions of 78
pigmentary variant of 78
Polymerase chain reaction 59
Polymyositis 94
Popliteal fossa 22, 40
Positive patch test reactions, relevance of 40
Postherpetic neuralgia 15
Post-steroid hypopigmentation 77
Potassium hydroxide 9f, 77
Prednisolone 52, 53, 124
Pregabalin 17
Prick test 29
Progressive itchy rash 8f
Progressive skin lesions 89
Prostaglandins 15
Pruriginous atopic eczema 14
Prurigo nodularis 11, 14, 15b, 16, 18, 85, 87, 124, 126, 127, 127t
clinical grade for 15b
diagnosis of 85
Prurigo pigmentosa 95, 96
histopathological features of 95f
rash of 94f
Pruritic bullous lesions 44
Pruritic dermatitis 22
Pruritic eruption 117
Pruritic papules 85
Pruritus 22, 69, 74, 83, 104, 108
Psoriasiform epidermal hyperplasia 85
Psoriasis 21, 63, 77
Psoriatic arthritis 60
Psychiatric disorders 15
Purpuric macules 89f
Pustular rash 65
R
Rabies 36
Randomized controlled trials 74
Rapid-eye-movement sleep 37
Rash 38, 94f
Renal transplantation 3
Retinoids 110
Rheumatoid arthritis 60
Rhinitis, allergic 14, 21, 52
Rubella 36
Ruxolitinib 60
S
Sarcoptes scabiei 90f, 100, 101, 114, 121, 123
Scabies 21, 63, 91, 102, 112, 116, 120
incognito 99f, 102t
diagnosis of 112, 115
types of 115, 115t
Scabietic vasculitis 91
Scaly patches 39f
Scleroderma 94
Scoring atopic dermatitis 52, 62, 66, 69
index 72
scale 4
score 35
Seborrhea 77
Septate hyphae 9f
Serpiginous burrow 114f
Severe eczematous dermatitis 19
Sézary disease 32
Sézary syndrome 58
Simvastatin 89
Skin
biopsy 77, 90, 90f, 107
celiac disease of 119
eruptions 73f
generalized dryness of 40
infection 91
inflammatory disease 73
lesions 58f, 76f, 86f, 118f
prick tests 52, 85
swelling of 112
Spleen tyrosine kinase 60
Staphylococcus aureus 59
Stevens–Johnson syndrome 48
Stratum corneum 101
Sulfonamides 110
Sunset yellow dye, structure of 50f
Sweating 22
Systemic immunosuppressive therapies 61
T
Tacrolimus, topical 110
Tactile hallucinations 15
T-cell-driven complex inflammatory skin disease 74
Telmisartan 89
Tetracycline 96, 110
Thalidomide 17, 124
Therapy-resistant dermatitis 41
Thermal burns 67
Thymic stromal lymphopoietin 59
Thyroid disease 15
Tinea
corporis 77
incognito 9
infection 9
versicolor 77
Tofacitinib 60
Total prostatic-specific antigen 11
Toxocara canis 11
Trichophyton mentagrophytes 9
Tuberous sclerosis, ash leaf macules of 77
Tyrosine kinase 60
U
Ulcerative colitis 60
Ultraviolet light
A 124, 126
B 124, 126
United Kingdom Working Party's Diagnostic Criteria 22
Upadacitinib 60
Urticaria 104
chronic spontaneous 46
Urticarial vasculitis 93
V
Varicella-herpes zoster virus 60
Vasculitis, cutaneous 91
Viremia 59
Visual analog sleep 86
Visual analogue scale 14, 25, 124, 126
Vitiligo 77
W
White blood cell 62
White dermographism 22
Wiskott–Aldrich syndrome 67
Wood's lamp 77
X
Xerosis 22, 39f
Y
Yellow fever 36
vaccine 36
Z
Zika virus 14
×
Chapter Notes

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