Embryology & Anomalies of the Facial Nerve and Their Surgical Implications Robert Thayer Sataloff, Johnathan Brandon Sataloff
INDEX
Page numbers followed by f refer to figure.
A
Abnormalities of facial nerve 169
Acoustic nerve 60f
Alar and basal laminae in myelencephalon 61f
Albers-Schönberg disease 178
Anemia 178
Anterior inferior cerebellar artery 57f
Appearance of malformed auricle 146f
Atresia of esophagus 180
Auricular development 145
Autosomal recessive
osteopetrosis 178
syndrome 179
B
Bell's palsy 169, 173
Benign osteopetrosis 177
Bifurcation of
chorda tympani nerve 162
facial nerve 161
Bill's bar 105f
Blepharospasm 176
Bogorad's syndrome 171
Bony
overgrowth of facial bones 174
spiral lamina 110
Brain-derived neurotrophic factor 115
Branches of facial nerve 55f
Branchial arches 8f, 13f
Buccal branch 54f
Bulbopontine paralysis 171
C
Canaloplasty 136
Cartilaginous cells 88f
Cervical
branch 54f
lamina 70
part of platysma 70
Chondrocranium 6
Chronological development of facial nerve 34
Computed tomography 126
Computerized tomography 104f
Congenital
and hereditary facial paralysis 169
anomalies of temporal bone 172
facial
diplegia 174
paralysis 169
heart disease 172, 180
Conjoined twins 172
Course of facial nerve anterior to superior semicircular canal 52f
Cranial portion of central nervous system 61f
Craniometaphyseal dysplasia 174
Current theory of origin of ossicles 108f
D
Deafness 178
Dehiscence of facial nerve 158
Deiters' cells of organ of Corti 110
Deleted chromosome syndrome 172
Depressor
anguli oris 70
labii inferioris 70
Dermatocranium 6, 10
Development of
brain case 6
cochlea and ductus reuniens 82f
cranial nerves 68f
facial nerve 69f, 103f
motor nuclei and roots of 6th and 7th cranial nerves 62f
parotid gland around facial nerve 80f
pontine flexure 61f
premuscle masses of cephalic muscles 69f
tubotympanic recess and primordial masses of ossicles 71f
Diabetes mellitus 173
Digastric muscles 24
DiGeorge syndrome 173, 174
Dominant craniometaphyseal dysplasia 174
Dorsum of seven-somite human embryo 59f
Down syndrome 182
Duchenne's syndrome 169
Dystrophia myotonica 174
E
Embryology of
facial nerve 2, 29
intracranial portion of facial nerve 56
Epiphora 176
Eustachian tube 85f
Evolution of mammalian middle ear bones 23f
External
appearance of right side of central nervous system 60f
auditory canal 127f, 133f, 161
gill flap 12
Extracranial portion of facial nerve 53f
Extratemporal anatomy of facial nerve 53f
F
Facial
expression 22
nerve 34, 36, 40, 4244, 46, 53f, 60f, 62, 66, 75, 75f, 76f, 83, 85f, 89f, 90f, 91f, 93, 103f, 125, 132, 133f, 136, 137f, 150f, 152, 155, 159
abnormalities 170
anomalies 162
disorders 169
paralysis 180
paralysis 174, 178
Fallopian canal 97f, 133f, 162, 179
dehiscence 102f
Fibroblast growth factor 112
G
Goldenhar's syndrome 175, 176
Guillain-Barré syndrome 169
H
Hair cells 110
Headache 176
Hemifacial microsomia 175
Hensen's cells 110
Hereditary acoustic neuromas 176
Herpes zoster oticus 169
Horizontal semicircular canal 95f
Hyperhidrosis 176
Hypogeusia 176
I
Infectious diseases 169
Inferior part of orbicularis oris 70
Internal auditory canal 57f, 89f, 94f, 103f, 105f
Intracranial portion of facial nerve 56, 57f
Intratemporal blood supply of facial nerve 58f
Isolated anomalies of facial nerve 155
J
Jaw
articulation 20f
suspension 10
L
Labyrinthine portion of facial nerve 105f
Lacrimal gland 54
Locomotion 16
M
Magnetic resonance imaging 104f
Mandibular lamina 70
Marginal mandibular branch 54f
Masson trichrome staining 94f
Mastoid air cells 174
Meckel's cartilage 9, 10, 12, 18, 24, 98, 108f, 132, 134, 136
Melkersson-Rosenthal syndrome 176
Mobius' syndrome 162, 176, 177
Multiple sclerosis 169
Muscles of facial expression 25f
Mylohyoid muscles 24
N
Nasal
capsule 9
dorsum deformity 174
glands 54
O
Obliteration of paranasal sinuses 174
Optic capsule 9
Organ of Corti 110
Origin of anterior inferior cerebellar artery 57f
Ossicular mass 127f
Osteomyelitis 178
Osteopetrosis disease 177
Otic capsule 132
P
Palatine mucosal glands 54
Parotid
gland 94f
primordium 76f, 78f
Partial
DiGeorge syndrome 173
fallopian canal dehiscence 148
Phylogeny of facial nerve 5
Pierre Robin syndrome 178
Pillar cells 110
Portion of
facial nerve 90f, 107f, 125, 140f
Meckel's cartilage 88f
prosthesis 151f
Progressive sensorineural hearing loss 171
R
Ramsay Hunt syndrome 169
Recessive craniometaphyseal dysplasia 179
Reichert's cartilage 98, 108f, 130, 132, 148150, 158
Remnant of Meckel's cartilage 101f
Resection of rudimentary ossicular mass 144f
S
Sclerosteosis 179
Semicircular ducts 90f
Sensorineural hearing loss 174
Severe ossicular malformation and middle ear hypoplasia 140
Sickle-cell
crisis 180
disease 180
Small
portion of facial nerve 99f
segment of chorda tympani nerve 103f
Sturge-Weber syndrome 183
Stylomastoid foramen 53f, 94f
Subarcuate fossa 156f
Submandibular gland 54
Superior
semicircular canal 95f
vestibular nerve 89f
Syndrome of
bilateral acoustic nerve tumors 176
crocodile tears 171
T
Temporal branch 54f
Tensor tympani 85f
Thalidomide
embryopathy 162
induced malformations 180
Thrombocytopenia 178
Thymic
agenesis 173
hypoplasia 173
Tip of prosthesis 150f, 151f
Tongue fibrillations 171
Transversus nuchae muscles 70
Treacher Collins syndrome 180
Trifurcation of facial nerve 162
Trigeminal nerve 12
Trisomy
13 syndrome 181
18 syndrome 181
21 syndrome 182
Tuberous sclerosis 183
Tympanic membrane 138
Tympanoplasty 136
V
Van Buchem's disease 182
Vascular endothelial growth factor 114
Vertical portion of facial nerve 84f
von Recklinghausen's neurofibromatosis 183
Z
Zygomatic
arch 148
branch 54f
Zygomaticotemporal nerve 86
×
Chapter Notes

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1Embryology & Anomalies of the Facial Nerve and Their Surgical Implications2
3Embryology & Anomalies of the Facial Nerve and Their Surgical Implications
Second Edition
Robert Thayer Sataloff MD DMA FACS Professor and Chairman Department of Otolaryngology–Head and Neck Surgery Senior Associate Dean for Clinical Academic Specialties Drexel University College of Medicine Philadelphia Pennsylvania USA Johnathan Brandon Sataloff Amherst College Amherst, Massachusetts, USA Research Associate American Institute for Voice and Ear Research Department of Otolaryngology–Head and Neck Surgery Drexel University College of Medicine Philadelphia Pennsylvania USA
4
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Embryology and Anomalies of the Facial Nerve and Their Surgical Implications
First Edition: 1991
Second Edition: 2014
9789351522409
Printed at:
5
Dedication for the Second Edition
To
Dahlia M Sataloff md facs
Clinical Professor
Department of Surgery
The University of Pennsylvania
Chair, Department of Surgery
Pennsylvania Hospital, USA
Wife, mother, and friend
Dedication from the First Edition
To
My father, partner, and best friend
Joseph Sataloff MD DSC
whose guidance and inspiration are largely responsible
for any successes I have enjoyed in my profession
6
7PREFACE
This book is the result of more than 10 years of inquiry. It began when the senior author (Robert Thayer Sataloff) was a resident in the Department of Otolaryngology–Head and Neck Surgery at the University of Michigan, USA. The teaching at that time suggested that the location of the facial nerve in congenitally malformed ears was unknown. This produced uncertainty and fear in the otologic surgeon. In fact, many otolaryngologists were opposed to corrective surgery for hearing improvement, especially in patients with unilateral malformations, believing that the risk of facial paralysis was greater than the potential gain. It seemed to the author that if one understood the embryology of the facial nerve, it would be possible to make a reasonably accurate prediction of facial nerve position in most cases. However, when the authors went to the library to look up facial nerve embryology and correlate it with embryology of the ear, the literature review was almost more challenging than the surgery itself.
Some of this book is based on a study that was undertaken to help solve the practical clinical problem of facial nerve localization in surgical candidates with congenitally malformed ears. This study won the Edmund Prince Fowler Award for basic research, presented by the American Rhinological, Laryngological and Otological (Triological) Society in 1989. Since the first edition of this book was published in 1991, there has been very little new information discovered about gross embryology of the facial nerve. However, there has been substantial progress in understanding facial nerve differentiation and migration. A summary of the latest research is included in the second edition as well as new chapter on phylogeny. The authors hope that the information in this book will prove convenient and practical for otologic surgeons and students of otologic embryology and will facilitate review of this fascinating subject.
Robert Thayer Sataloff
Johnathan Brandon Sataloff
8
9
ACKNOWLEDGEMENTS
to the Second Edition
The authors are indebted again to Mary J Hawkshaw, BSN, RN, CORLN for her invaluable help in writing this book, to Debbie Keeler for preparation of the manuscript, and to everyone acknowledged in the first edition.10
11
ACKNOWLEDGEMENTS
to the First Edition
I am deeply indebted to many people for assistance in the preparation of this book. First, my deepest appreciation goes to my father, Joseph Sataloff, who inspired me to enter otolaryngology and advised me to train at the University of Michigan, and who has continued to share his wisdom with me throughout our years in practice together. The academic and clinical training I received from Walter P Work, Charles J Krause, Malcolm D Graham, and others in Ann Arbor has been invaluable; as was my exposure in Los Angeles with Bill and Howard House and their associates. I am indebted to all of my mentors for helping prepare me to write this text. This work was also aided immeasurably by Merle Lawrence, PhD, who was kind enough to permit me to study his collection of embryology slides. I am also indebted to Kyle Rarey, PhD, for making Dr Lawrence's slide collection available to me again recently, for reassessment and for his invaluable assistance in reviewing histologic materials. It is impossible to thank adequately my friend and colleague Zaven Jabourian, MD. During his first and second years in practice as an otolaryngologist, he generously donated his time, talent and friendship to render the illustrations in this book. They are superb, and the fact that they were drawn by an otolaryngologist made the process immeasurably easier. A very special debt of gratitude goes to Mary Hawkshaw, RN, BSN, my nurse, editorial assistant, and patient friend, who devoted almost as many hours to this manuscript and its photographs as I did. Without her dedicated and expert assistance, preparation of this book probably would have taken another year or two. I also express my gratitude to Helen Caputo, who retyped the manuscript more times than either of us can count, and to Kathy Mayer for her assistance in labeling the illustrations. Finally, I express deep appreciation to my understanding and tolerant wife, Dahlia Sataloff, MD, who put up with innumerable ruined evenings, weekends, vacations, and summer trips while I was engrossed in completing this project.
I am indebted to the Triological Society and the Laryngoscope for permission to republish materials from my article “Embryology of the Facial Nerve and Is Clinical Applications”, including portions of the text and Table 2, and Figures 18, 21, 24, 31, 33, 40–44, 47, 49–53, 56–58, 60, 62–65.