The Short Textbook of Medical Helminthology Satish Gupte
INDEX
Page numbers followed by f refer to figure and t refer to table
A
Albendazole 125
Allergic syndrome 6
Alopecia 127
Amnesia 56
Ancylostoma
braziliense 35, 68
caninum 9, 68, 114
duodenale 3, 5, 6, 30, 34, 35, 120
lesions of 32f
life cycle of 31f
morphology of 30f
secreted proteins 120
Anemia, severe 18
Angioneurotic edema 130
Angiostrongyliasis 115
Angiostrongylus cantonensis 69, 115
Anorexia 33, 130
Aphasia 56
Appendicitis, acute 18
Artemethur 133
Artemisinin derivatives 133
Artesunate 133
Artificial fertilizer 51
Ascariasis 125, 127, 130
Ascaris 132
lumbricoides 1, 37, 9, 2629, 132
adult worms of 25
vermicularis 4
B
Bacterial infection 93
Baylisascaris procyonis 114, 115
Beef tapeworm 47
Bile duct epithelium and carcinogen exposure, hyperplasia of 106
Biomphalaria
alexandrina 75
glabrata 75
pfeifferi 75
Blindness 56
Blood flukes 104
Bloody diarrhea 18
Blurred vision 56
Bronchospasm 127
Brugia
bancrofti 7
malayi 57, 95, 98, 118, 132
microfilaria of 96f
C
Capillaria
aerophilia 113
hepatica 113
philippinensis 113
Capillariasis 113
Caridina 36
Casoni's test 84, 86
Cerebrospinal fluid 125
Cestodes
features of 2
intestinal 128
Charcot Leydin crystals 29
Chinese liver fluke 35
Chlonorchis sinensis 36
Clonorchiasis 125, 129
Clonorchis sinensis 37, 35, 37, 104, 106, 131
life cycle of 36f
Congestive heart failure 18
CpG islands, aberrant hypermethylation of 107
Cramps, abdominal 131
Crystoluria 130
Cutaneous larva migrans 67, 125, 130, 132
Cysticercosis 22, 125, 129, 131
Cysticercus
bovis 50
cellulosae 55, 55f
D
Dexamethasone 126
Diarrhea 33, 127, 12931
Diatoma sinensis 35
Diethylcarbamazine 126
Diphyllobothriasis 129
Diphyllobothrium latum 2, 4, 5, 7, 4143
life cycle of 43f
Dipylidium caninum 4
Distomat buski 38
Dizziness 128130
Dracunculiasis 7
Dracunculus medinensis 36, 62, 64
extraction of 64f
life cycle of 63f
Dragon worm 61
Drowsiness 128, 130
Drug metabolizing enzymes, activation of 106
E
Echinococcosis 80, 126
hydatidosis 80
Echinococcus 132
granulosus 2, 7, 80, 83, 86, 87, 122, 131
life cycle of 82f
morphology of 81f
multilocularis 80, 88, 89
Emerging helminthic infections 111
Encephalitis 56
Enterobius vermicularis 37, 22, 23, 109, 132
life cycle of 24f
morphology of 23f
Enzyme linked immunosorbent assay 47
Eosinophilic enteritis 114
Epigastric discomfort 33
Epilepsym, Jacksonian type of 56
Esophagostomiasis 112
F
Fasciola hepatica 4, 5, 7, 10, 38, 6567, 131, 132
life cycle of 66f
Fasciolopsis buski 3, 4, 38, 39
life cycle of 39f
Ferrissia tenuis 71, 72
Fever 126, 129
Filaria
bancrofti 90
sanguinis hominis 90
Filarial worms 1
Filariasis 8, 90, 132
lymphatic 125
Flukes, intestinal 132
Food borne trematode infections 8
G
Gastrointestinal disorders 130
Giant intestinal fluke 38
Gnathostoma 111
binucleatum 111
spinigerum 69
Gnathostomiasis 111
Gordius medinensis 4
Guinea worm 61
infection 6
H
Headache 126131
Helminth
infections, treatment of 131t
pathogenic role of 5
Helminthiasis 4
Helminthic
disease 5, 6
gastrointestinal nosocomial infections 109
parasites, vaccines in 120
vaccines 119, 122
Helminths 1
causing nosocomial infections 109t
features of 2
infections, control of 118
intestinal 11
worldwide
prevalence of 6t
status of 7
Hemorrhage 33
Hepatitis 105, 130
Hepatocellular carcinoma 105
Hookworm 1, 127, 130, 132
disease 6
vaccines for 120
infection 126
Human anti-helminthic disease vaccines 122, 122t
Hydatid
cyst 84
fate of 85
morphology of 82f
disease 80, 122
sand 84
Hydrocephalus 56
Hymenolepis nana 2, 57, 44, 46, 109, 131, 132
life cycle of 46f
morphology of 45f
Hymenolepsiasis 129
I
Infection, sources of 6
Intense prutitus 33
Intestinal helminthiasis, treatment of 124
Ivermectin 125
K
Katayama syndrome 78
manifestations of 78
L
Larva 20
migrans 67
Liver fluke 104
infections 106
Loa loa 7, 97, 132
microfilaria of 98f
Loeffler's syndrome 29
Loiasis 125
Lymph node, fibrosis of 93
Lymphangitis, causes of 93
Lymphatic
obstruction, causes of 93
vessels, fibrosis of 93
M
Macracanthohynchus hirudinaceus 10
Maculopapular rash 33
Magnetic resonance imaging 85
Malaise 129
Manson's blood fluke 74
Mansonella
ozzardi 7
perstans 7
Mansonia annulifera 96, 97
Mebendazole 126
Membrane filtration 94
Metrifonate 127
Muscle
biopsy 14
digestion 14
enzymes 14
Myalgia 126
N
Nausea 33, 126, 127, 128, 129, 130
Necator americanus 3, 5, 6, 34, 68, 120, 122
morphology of 34f
Nematodes
features of 3
significance of 3
Neurocysticercosis 107
Niclosamide 128
Nitazoxanide 132
Non-food substances, ingestion of 18
Nosocomial infections 110
O
Obliterate endolyphangitis 93
Obstruction, lymphatic 5, 94
Occult filariasis 94
Oesophagostomum bifurcum 112
Onchocerca volvulus 99, 101, 122, 132
Onchocerciasis 125
Oncogenic helminths 104
Opisthorchiasis 129
Opisthorchis
felineus 8, 104, 106
sinensis 35
viverrini 104, 106
infection 106
Oriental lung fluke 58
Oxamniguine 128
P
Pain, abdominal 126, 127, 129
Paloemonetes sinensis 36
Paragonimiasis 129, 131
Paragonimus westermani 3, 4, 6, 7, 58, 60, 61, 131
life cycle of 60f
Phylum
nemathelminthes 1
platyhelminthes 1
Pinworm infection 6
Pork tapeworm 52
Praziquantel 126, 129
Pruritis 126, 128
Pulmonary distomiasis 58
Puritis 129
Pyrantel pamate 129
R
Radical allergosorbent test 21
Reversible alopecia 126
River blindness 122
S
Saponin lysis 94
Schistosoma
haematobium 3, 5, 6, 71, 73, 75, 104, 105, 121, 122, 127
infection 74, 105
life cycle of 72f
japonicum 6, 10, 75, 7779, 104, 105, 122, 133
life cycle of 78f
mansoni 5, 6, 10, 74, 76, 104, 105, 119, 122
infections 128
life cycle of 75f
Schistosomes 1, 104, 132
Schistosomiasis 71, 127, 128, 129
vaccines for 121
Seizures 128, 130
Serpent worm 61
Simulium
damnosum 118
neavei 118
Skin test 15
Stevens-Johnson syndrome 130
Streptomyces avermitilis 125
Strongyloides
stercoralis 2, 6, 7, 1922, 68, 109, 110, 132
infection 21
life cycle of 20f
Strongyloidiasis 6, 125, 130
Subcutaneous nodules 56
Swimmer's itch 78
T
Taenia
cucurbitina 52
latum 4
saginata 2, 5, 7, 47, 48, 51, 53, 54, 131, 132
life cycle of 50f
morphology of 48f
solium 2, 47, 5256, 104, 107, 109, 121, 122, 131
adult worms of 52f
cysticercus 55
life cycle of 53f
Thiabendazole 130
Thrombocytopenia 127
Tissue helminths 58
Toxocara canis 7, 68, 69
Toxoplasma gondii 7
Trematodes
features of 2
intestinal 129
Trichina worm 11
Trichinella spiralis 3, 6, 7, 11, 14f, 119
life cycle of 13f
pathogenesis of 12f
Trichinellosis 126, 127
Trichostrongyloidiasis. 127, 130
Trichuriasis 126, 127
Trichuris trichiura 1, 57, 15, 18, 132
life cycle of 17f
morphology of 16f
V
Vertigo 127
Visceral larva and migrans 126, 127, 130, 132
Vomiting 126128, 130
W
Wuchereria
bancrofti 5, 6, 8, 90, 92, 93, 9598, 118, 132
diagnosis of 94
life cycle of 92f
microfilaria of 91f
malayi 95
pacifica 90
X
Xenodiagnosis 14
×
Chapter Notes

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1The Short Textbook of Medical Helminthology2
3The Short Textbook of Medical Helminthology
Satish Gupte MD Professor and Head Department of Microbiology Gian Sagar Medical College and Hospital Ram Nagar, Rajpura, Punjab, India
4
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The Short Textbook of Medical Helminthology
First Edition: 2015
9789351526179
Printed at
5PREFACE
Helminthiasis, especially filariasis and schistosomiasis are constantly posing health problems, especially in resource-limited populations. In spite of research work all over the world, helminthic infection control, treatment and preventon measures are not up to the mark.
Needless to add that complexity of problem has gained momentum because of unchecked population multiplication, poor socioeconomic conditions and poor sanitation, especially in developing countries. To add fuel to this crisis, we have so far failed to develop vaccines against helminths. Thus, helminths are having a field day to cause morbidity. However, a lot of work is in progress in this direction. Hopefully, in foreseeable future, we may get effective vaccine(s) against helminths.
Though helmiths are more prevalent in tropical countries, they have become a factor of concern all over the world in one way or the other. Sufferers include inhabitants of developed and developing countries, poor and rich alike. These worms have vital role to play in causing malnutrition, growth retardation, malignancy and what not.
The present book, The Short Textbook of Medical Helminthology aims at a comprehensive, reasonably illustrated and state-of-the-art update of helminths, a universal cause of morbidity and mortality.
Apart from routine worm description, the book provides discussion on such interesting topics as Emergence of Helminthic Infections, Helminthic Nosocomial Infection, Oncogenic Helminths, Control, Prevention and Vaccines, Treatment, etc. Hot topics like Schistosomiasis, Filariasis and Hydatidosis are discussed with up-to-date information. The book is adequately illustrated as well.
Hopefully this book with meaningful illustrations and up-to-date information shall be welcomed by the academicians and all those interested in helminths and allied issues.
I look forward to suggestions and constructive critical comments for bringing out improved future editions.
Satish Gupte
6
7ACKNOWLEDGMENTS
At the very outset, I am grateful of M/s Jaypee Brothers for giving me the honor to pen down the book The Short Textbook of Medical Helminthology. In this regard my special thanks are due to Shri Jitendar P Vij, Group Chairman, for meaning cooperation and interaction from time to time in bringing out this volume within short time without compromising on production quality.
To the management and administration of Gian Sagar Medical College and Hospital, I respectfully take the opportunity to say “thank you”.
I am thankful to my brother, Dr Suraj Gupte, Professor and Head, Postgraduate Department of Pediatrics, Mamta Medical College and Hospitals, Nellore, South India. In actuality, it was he who convinced me about the compelling need for such a book, assuring full help towards this assignment. He is a source of inspiration and role model for me.
My thanks are due to faculty members especially Dr Prerna Aggarwal, Dr Maninder, Dr Manju Bala, late Dr Ashok Kumar Chopra and Dr Ashwini Manhas of Microbiology Department, Gian Sagar Medical College and Hospital for critical constructive comments and for helping me to compile such topics as “Oncogenic Helminths, Emerging Helminthic Infections, and Control, Prevention and Vaccines and Treatment”.
My gratitude to my wife and Managing Editor, Jyotsna Gupte, and son, Anubhav Gupte, for their contribution in various ways in the preparation of manuscript.
I am thankful to Mr Gurpreet Singh and Ms Kavita Arora for secretarial work and excellent typing of the manuscript in record time.
It is a pleasure to express my gratitude to Ms Preety Nagpal, Ms Rishu Sharma and Ms Puneet Kaur for furnishing the line illustrations.