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Case Compendium in Endocrinology
Sarita Bajaj, Romesh Khardori, Smita Gupta
CHAPTER 1:
Primary Ovarian Insufficiency
Pertinent Investigations for Evaluating a Case of Amenorrhea
DIFFERENTIAL DIAGNOSIS
Discussion
Clinical Features
Management
CHAPTER 2:
Subacute Thyroiditis
Laboratory/Imaging Evaluation
Differential Diagnosis
Discussion
Course And Management
CHAPTER 3:
Graves’ Disease
Differential Diagnosis
Investigations
Management
DISCUSSION
Antithyroid Drugs
Surgery
RAI Ablation
Conclusion
SUGESSTED READINGs
CHAPTER 4:
Vanishing Pituitary Tumor
Differential Diagnosis
INVESTIGATIONS
DIAGNOSIS
MANAGEMENT
DISCUSSION
Definition
Epidemiology
Pathology
Clinical Features
Diagnosis
Imaging
MANAGEMENT
CHAPTER 5:
Unusual Cause of Hypocalcemia in a Young Male
PROBABLE DIAGNOSIS
Investigations
RADIOLOGICAL INVESTIGATIONS
MANAGEMENT
DISCUSSION
Pathophysiology
Classification
Genetics
Diagnosis
Treatment and follow-up
CHAPTER 6:
Non-parathyroid-mediated Hypercalcemia
Laboratory Investigations
Special Studies
DIFFERENTIAL DIAGNOSIS
APPROACH TO HYPERCALCEMIA
DISCUSSION
MANAGEMENT
CHAPTER 7:
Secondary Hyperparathyroidism
Introduction
DISCUSSION
CHAPTER 8:
Juvenile Hypothyroidism Presenting as Precocious Puberty
Investigations
DISCUSSION
Differential Diagnosis of Incomplete GnRH-Independent Isosexual Precocious Puberty in a Female (Table 8.1)
Thyroid Disease in Childhood and Adolescence
Chronic Lymphocytic Thyroiditis
Thyroid Dysgenesis and Inborn Errors of Thyroid Hormonogenesis
Iodine and Other Micronutrient Deficiency: Natural Goitrogens
Clinical Manifestations
Laboratory Evaluation
Treatment of Acquired Hypothyroidism in Children
CHAPTER 9:
Hypopituitarism: Sheehan's Syndrome
DIFFERENTIAL DIAGNOSIS
INVESTIGATIONS
TREATMENT
DISCUSSION
Conclusion
CHAPTER 10:
Hyperparathyroidism
Differential Diagnosis
Pertinent Investigations
MANAGEMENT
DISCUSSION
ETIOLOGY AND PRESENTATION
Epidemiology
Risk Factors
Indian Scenario
Clinical Manifestations
Elevated PTH without Hypercalcemia
Normoparathyroid Hypercalcemia
NATURAL COURSE
Biochemical/Laboratory Investigations
Familial Forms
Renal Function and Further Specialized Tests
Imaging Studies
TREATMENT OPTIONS
Asymptomatic Primary Hyperparathyroidism
Surgical Treatment
Postoperative Course and Long-Term Prognosis
Persistent or Recurrent Primary Hyperparathyroidism
Medical Management of Primary Hyperparathyroidism
CHAPTER 11:
Diabetic Ketoacidosis with Cerebral Edema
CLINICAL and LABORATORY DATA
Differential Diagnosis: Polyuria, Polydipsia, Dehydration, and Weight Loss
MANAGEMENT
DISCUSSION
Diagnostic Criteria
Severity of Diabetic Ketoacidosis
Cerebral Edema
Pathophysiology
Warning Signs of Cerebral Edema
Diagnostic Criteria
Major Criteria
Minor Criteria
Prevention and Therapy of Cerebral Edema
CHAPTER 12:
Polycystic Ovarian Syndrome
Physical Examination
Laboratory Investigations
Abdominal USG (Ultrasonography)
Differential Diagnosis
Treatment Options
DISCUSSION
Diagnosis of Polycystic Ovarian Syndrome
Pathophysiology of Polycystic Ovarian Syndrome
Clinical Features of Polycystic Ovarian Syndrome
Menstrual Abnormalities
Hyperandrogenism
Infertility
Metabolic Consequences of Polycystic Ovarian Syndrome
Quality of Life and Mental Health in PCOS
Cancer Risk in Polycystic Ovarian Syndrome
Conclusion
CHAPTER 13:
Addison's Disease/Adrenal Crisis
Differential Diagnosis
Evaluation
Management
DISCUSSION
Clinical Presentation
Laboratory Diagnosis
Imaging
Treatment
CHAPTER 14:
Hirsutism
Introduction
INVESTIGATIONS
DISCUSSION
Conclusion
CHAPTER 15:
Acromegaly
Differential Diagnosis
Management
DISCUSSION
Initial Diagnostic Approach
CHAPTER 16:
Cushing's Disease
DIFFERENTIAL DIAGNOSIS
Investigations
DISCUSSION
Establishing the Diagnosis of Cushing's Disease
Screening Tests
Establishing the Cause of Cushing's Disease
8-mg Dexamethasone Suppression Test
Corticotropin Releasing Hormone Simulation Test
Management of Cushing's Disease
Initial Management
Treatment of Persistent or Recurrent Disease
Conclusion
CHAPTER 17:
Secondary Amenorrhea and Hyperprolactinemia in a Young Female
INVESTIGATIONS
EXAMINATION
DIFFERENTIAL DIAGNOSIS
HOSPITAL COURSE
DISCUSSION
Germ Cell Tumors
CASE IN CONTEXT
SUGGESTD READINGs
CHAPTER 18:
Diabetes Insipidus
DISCUSSION
DIAGNOSIS
MANAGEMENT
CHAPTER 19:
Dizzy Spells in an Elderly Female
DIFFERENTIAL DIAGNOSIS (POSTURAL HYPOTENSION, PAROXYSMAL HYPERTENSION, ABDOMINAL PAIN, AND FEVER)
Laboratory Data
Urine Studies
DIAGNOSIS
DISCUSSION
Biochemical Testing for Diagnosis
Localization
Genetic Testing
Treatment and Management
CASE IN CONTEXT
CHAPTER 20:
Post-meal Leg Cramps: An Interesting Case of Hypokalemia
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC WORKUP
DISCUSSION
TREATMENT
FOLLOW-UP
CHAPTER 21:
Multiple Endocrine Neoplasia Type 1
DIFFERENTIAL DIAGNOSIS
Pertinent investigations
MANAGEMENT
DISCUSSION
CHAPTER 22:
Multiple Endocrine Neoplasia Type 2
DIFFERENTIAL DIAGNOSIS
INVESTIGATIONS
MANAGEMENT
DISCUSSION
Conclusion
CHAPTER 23:
Unusual Case of Hypoglycemia
HOSPITAL COURSE
DISCUSSION
Historical Perspective
Incidence
Demographics
Pathophysiology
Symptoms and Signs
DIFFERENTIAL DIAGNOSIS
DIAGNOSIS
Treatment
Medical Therapy
Radiation Therapy
Therapy for Metastatic Disease
CHAPTER 24:
Ectopic Adrenocorticotropic Hormone Syndrome
DIFFERENTIAL DIAGNOSIS
PERTINENT INVESTIGATIONS
MANAGEMENT
DISCUSSION
Conclusion
CHAPTER 25:
ACTH-Independent, Cushing's Syndrome Secondary to Primary-pigmented Nodular Adrenal Hyperplasia Associated with Carney's Complex
DIFFERENTIAL DIAGNOSIS
MANAGEMENT
DISCUSSION
Carney Complex
Hypokalemia and Cushing's Syndrome
Pregnancy and Cushing's Syndrome
TREATMENT
CHAPTER 26:
Vitamin D Toxicity
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
MANAGEMENT
DISCUSSION
CLINICAL MANIFESTATIONS
DIAGNOSIS OF VITAMIN D TOXICITY
TREATMENT
CHAPTER 27:
Diabetes Mellitus in Hypopituitarism
LABORATORY INVESTIGATIONS
IMAGING STUDIES
DIAGNOSIS
TREATMENT
DISCUSSION
INDEX
TOC
Index
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