Edited by Burke A. Cunha, MD, MACP Chief, Infectious Disease Division Winthrop-University Hospital Mineola, New York Professor of Medicine State University of New York School of Medicine Stony Brook, New York fm3ABOUT THE EDITOR DEDICATION fm7EDITORS CONTRIBUTORS

• Burke A. Cunha, MD, MACP
• Chief, Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• Professor of Medicine
• State University of New York
• School of Medicine
• Stony Brook, New York
• All chapters except HIV Infection & Pediatric ID

• Jeffrey Baron, PharmD
• Clinical Pharmacist
• Winthrop-University Hospital
• Mineola, New York
• HBV, HCV, and HIV Guidelines
• Antimicrobial Drug Summaries

• Edward J. Bottone, PhD
• Professor of Medicine
• Professor of Microbiology
• Professor of Pathology
• Mount Sinai
• School of Medicine
• New York, New York
• Medical Microbiology; Parasites, Fungi, Unusual Organisms

• John L. Brusch, MD
• Associate Chief of Medicine
• Cambridge Health Alliance
• Infectious Disease Service
• Cambridge Health Alliance
• Medical Director, Somerville Hospital
• Assistant Professor of Medicine
• Harvard Medical School
• Boston, Massachusetts
• Endocarditis: Therapy & Prophylaxis

• Cheston B. Cunha, MD
• Director, Antibiotic Stewardship Program
• Rhode Island Hospital and The Miriam Hospital
• Infectious Disease Division
• Assistant Professor of Medicine
• Brown University Alpert School of Medicine
• Providence, Rhode Island
• Infectious Disease Differential Diagnosis Overview of Antimicrobial Therapy
  Empiric Therapy Based of Clinical Syndromes Antimicrobial Drug Summaries

• Daniel Caplivski, MD
• Infectious Disease Division
• Assistant Professor of Medicine
• Mt. Sinai School of Medicine
• New York, New York
• Fungal Stain Atlas

• Dennis J. Cleri, MD
• St. Francis Medical Center
• Professor of Medicine
• Seton Hall University
• School of Graduate Medical Education
• Trenton, New Jersey
• Bioterrorism

• Staci A. Fischer, MD
• Director, Transplant Infectious Diseases
• Rhode Island Hospital
• Infectious Disease Division
• Associate Professor of Medicine
• Brown University Alpert School of Medicine Providence, Rhode Island
• Transplant Infections: Therapy & Prophylaxis

• fm8Pierce Gardner, MD
• Senior Advisor, Clinical Research and Training
• National Institutes of Health
• John E. Fogarty International Center for Advanced Study in the Health Sciences
• Bethesda, Maryland
• Prophylaxis and Immunization

• Arthur Gran, MD
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York
• School of Medicine
• Stony Brook, New York
• Antimicrobial Drug Summaries

• Jean E. Hage, MD
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York
• School of Medicine
• Stony Brook, New York
• Empiric Therapy of Clinical Syndromes;
• Prophylaxis & Immunization;
• Parasitic & Fungi; Unusual Organisms;
• Antimicrobial Drug Summaries

• Mark H. Kaplan, MD
• Professor of Medicine
• Infectious Diseases
• University of Michigan School of Medicine
• Ann Arbor, Michigan
• HIV Drug Summaries

• Douglas S. Katz, MD
• Vice Chairman for Clinical Research and Education
• Director, Body CT
• Winthrop-University Hospital
• Mineola, New York
• Professor of Clinical Radiology
• State University of New York School of Medicine
• Stony Brook, New York
• Chest X-ray Atlas

• Raymond S. Koff, MD
• Clinical Professor of Medicine
• University of Connecticut School of Medicine
• Farmington, Connecticut
• Viral Hepatitis: Therapy & Prophylaxis

• Leonard R. Krilov, MD
• Chief, Pediatric Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• Professor of Pediatrics
• State University of New York
• School of Medicine
• Stony Brook, New York
• Pediatric Infectious Diseases

• David W. Kubiak, PharmD
• Infectious Disease Clinical Pharmacist
• Brigham and Women's Hospital
• Boston, Massachusetts
• Antiretroviral Drug Summaries

• Brian R Malone, BS, MS, RPh
• Director, Pharmaceutical Services
• Winthrop-University Hospital
• Mineola, New York
• Adjunct Affiliate Professor
• College of Pharmacy St. John's University
• Queens, New York
• Pediatric Drug Summaries

• George H. McCracken, Jr., MD
• Distinguished Professor of Pediatric Infectious
• Disease and the Sarah M. and Charles E. Seay
• Chair in Pediatric Infectious Disease
• University of Texas Southwestern Medical Center
• Dallas, Texas
• Pediatric Infectious Diseases

• James H. McGuire, MD
• Master Clinician
• Division of Infectious Diseases
• Brigham and Women's Hospital
• Professor of Medicine
• Harvard Medical School
• Boston, Massachusetts
• Parasites, Fungi, Unusual Organisms

• Nardeen Mickail, MD
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York School of Medicine
• Stony Brook, New York
• Antimicrobial Drug Summaries

• fm9Maria D. Mileno, MD
• Director, Travel Medicine
• The Miriam Hospital
• Infectious Disease Division
• Associate Professor of Medicine
• Brown University Alpert School of Medicine
• Providence, Rhode Island
• Prophylaxis and Immunizations

• Robert Moore, MD
• Chairman, Department of Radiology
• Stony Brook University Hospital
• Professor of Radiology
• State University of New York School of Medicine
• Stony Brook, New York
• Chest X-ray Atlas

• Sigridh Muñoz-Gomez, MD
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York
• School of Medicine
• Stony Brook, New York
• Antimicrobial Drug Summaries

• Ronald L. Nichols, MD
• William Henderson Professor of Surgery
• Professor of Microbiology and Immunology
• Tulane University School of Medicine
• New Orleans, Louisiana
• Surgical Antimicrobial Prophylaxis and Therapy

• Genovefa Papanicolaou, MD
• Attending Physician, Infectious Disease Service
• Memorial Sloan Kettering Cancer Center
• Associate Professor of Medicine
• Weill Cornell Medical College
• New York, New York
• Transplant Infections: Therapy & Prophylaxis

• Muhammed Raza, MBBS
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York
• School of Medicine
• Stony Brook, New York
• Antimicrobial Drug Summaries

• Michael F. Rein, MD
• Professor of Medicine (Emeritus)
• University of Virginia Health System
• Charlottesville, Virginia
• Sexually Transmitted Diseases

• John H. Rex, MD
• Adjunct Professor of Medicine University of Texas Medical School
• Houston, Texas
• Vice-President and Medical Director for Infection
• AstraZeneca Pharmaceuticals Macclesfield, UK
• Antifungal Therapy

• Paul E. Sax, MD
• Clinical Director, Division of Infectious Diseases and HIV Program
• Division of Infectious Diseases
• Brigham and Women's Hospital Associate Professor of Medicine
• Harvard Medical School
• Boston, Massachusetts
• HIV Infection

• David Schlossberg, MD
• Tuberculosis Control Program
• Philadelphia Department of Health
• Professor of Medicine
• Temple University School of Medicine
• Philadelphia, Pennsylvania
• Tuberculosis

• Paul E. Schoch, PhD
• Director
• Clinical Microbiology Laboratory
• Winthrop-University Hospital
• Mineola, New York
• Medical Microbiology and Gram Stains Atlas

• Daniel S. Siegal, MD
• Department of Radiology
• Mount Auburn Hospital
• Harvard Medical School
• Boston, Massachusetts
• Chest X-ray Atlas

• fm10Stephanie Strollo, MD
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York School of Medicine
• Stony Brook, New York
• Initial Therapy of Isolates Pending Susceptibility Testing

• Uzma Syed, DO
• Infectious Disease Division
• Winthrop-University Hospital
• Mineola, New York
• State University of New York School of Medicine
• Stony Brook, New York
• Initial Therapy of Isolates Pending Susceptibility Testing

• Damary C. Torres, PharmD
• Clinical Pharmacy Specialist
• Winthrop-University Hospital
• Mineola, New York
• Associate Clinical Professor of Pharmacy
• College of Pharmacy, St. John's University
• Queens, New York
• Antimicrobial Drug Summaries

• Kenneth F. Wagner, DO
• Infectious Disease Consultant
• National Naval Medical Center
• Associate Professor of Medicine Uniformed Services, University of the Health Sciences
• F. Edward Hebert School of Medicine
• Bethesda, Maryland
• Parasites, Fungi, Unusual Organisms

fm11ACKNOWLEDGMENTS NOTICE BASIS OF RECOMMENDATIONS fm12ABBREVIATIONS ABE ABM ADA AFB AIH AIHA AML ANA ARDS AG A-V β-lactams BAL BG BMT BPH CAB CABG CAC CAH CA-MRSA CAP CD₄ CE CFS CGD CIE CLL CML CMV CNS CO-MRSA CoNS CPH CPK CrCl CRE CSD CSF CT CVA CVC CVID CVVH CXR DFA DI DIC DM DOT e.g. EBV EEE EEG EIA ELISA EM EMB Enterobacteriaceae: ESBLs esp ESR ESRD ET EV EVD FTA-ABS FUO G6PD GC GCA GI gm GU GVHD HA-MRSA HAP HAV HBcAb HBoV HBsAg HBV HCV HD HDV HEV HFHD HFV HFM HGA HHV-6,7,8 HME hMPV HPS HPV HTLV-1 HRIG HSV I & D IFA IgA IgG IgM IM INH IP IT ITP IV IV/PO IVDA IVIG JE kg L LCM LDH LFTs LGV MAI MCD mcg mcL MDR MDRSP MERS mg mL MIC min MMR MPD MRI MRSA MRSE MS MSSA MSSE MTT MU MVP NDM NHAP NNRTI NP NRTI NSAIDs OI OPAT PAN PBC PBS PCEC PCN PCP PCR PD PDA PE PEP PI PID PML PMN PO PPD PPIs PPNG PTBM PVE PVL PZA q__d q__h q month q week RA RBC RE RMSF RSV RUQ RVA SARS SBE SCID SGOT/SGPT SLE St. LE SOT sp. SPB SPEP SQ STD TA TAA TAH/BSO TB TDF TEE TEN TID TMP TMP–SMX TPN TRNG TSS TTE TTP TURP UC UTI VA VAP VCA VEE VISA VLM VP VRE VRSA VSE VZV WBC WEE WNE XMRV yrs