Editor-in-Chief Ravi R Kasliwal
MD DM Chairman
Clinical and Preventive Cardiology Medanta Heart Institute Medanta—The Medicity Gurgaon, Haryana, India
Co-editor Manish Bansal
MD DNB (Cardiology) FACC FASE FISCU
Senior Consultant Cardiology Medanta—The Medicity Gurgaon, Haryana, India
Forewords Naresh Trehan
Gilbert Habib
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Applied Echocardiography in Coronary Artery Disease
First Edition: 2017
9789351529729
Printed at
5Dedicated to
The ‘fab four’ who would have truly appreciated this work and given a warm hug:
Prayag and Rajkumari Kasliwal
7Contributors
- Adrian Chong MBBS (Hons) BPharm FRACP FASE FCSANZ
- Cardiologist
- Department of Cardiology Princess Alexandra Hospital
- Mater Health Services
- University of Queensland
- Brisbane, Queensland, Australia
- Alina Nicoara MD FASE
- Assistant Professor of Anesthesiology Director, Perioperative Echo Service
- Duke University Health System
- Durham, North Carolina, USA
- Amrita Kushal MD
- Cardiovascular Fellow
- Lenox Hill Heart and Vascular Institute of New York
- New York, USA
- Anuj Mediratta MD
- Advanced Cardiovascular Imaging Fellow
- Section of Cardiology Department of Medicine
- University of Chicago
- Chicago, Illinois, USA
- Asrar Ahmed MD DM MRCP
- Clinical Research Fellow Department of Cardiovascular
- Medicine, Northwick Park Hospital
- Harrow, London, UK
- Ayman A Farag MD
- Instructor/Fellow Medicine-Cardiovascular Disease
- Department of Medicine
- Division of Cardiovascular Disease
- University of Alabama
- Birmingham, Alabama, USA
- Bijoy K Khandheria MD FACP FESC FASE FACC
- Clinical Adjunct Professor of Medicine University of Wisconsin
- School of Medicine and Public Health Milwaukee, Wisconsin
- Medical Director, Echocardiography
- Aurora Cardiovascular Services-Aurora
- Medical Group, Milwaukee, Wisconsin
- Co-Director
- Aurora Center for Cardio-Oncology Research and Innovation
- Milwaukee, Wisconsin, USA
- Brian Mott MD
- Fellow in Cardiology Knight Cardiovascular Institute,
- Oregon Health and Science University Portland, Oregon, USA
- Cheuk-Man Yu MD FACC FRCP
- Professor of Medicine and Therapeutics
- Division of Cardiology, Department of
- Medicine and Therapeutics
- Honorary Consultant
- Prince of Wales Hospital
- Director (Clinical Sciences)
- Institute of Vascular Medicine
- Director of Heart Education and
- Research Training (HEART) Center
- Faculty of Medicine
- Division of Cardiology and HEART
- Center
- The Chinese University of Hong Kong Hong Kong
- Divya Malhotra MD Diplomate American Board of Cardiovascular Disease Diplomate American Society of Echocardiography FACC FASE
- Head and Senior Consultant
- Department of Noninvasive Cardiology
- Max Superspecialty Hospital
- Saket, New Delhi, India
- Francesco Maffessanti PhD
- Postdoctoral Research Fellow Department of Medicine
- Section of Cardiology
- University of Chicago
- Chicago, Illinois, USA
- G Vijayaraghavan MD DM (Cardiology) FRCP (Lon) FRCP (Edin) FACC FAHA
- Vice Chairman and Director
- Dean Academics
- President SOCOMER
- Senior Consultant Cardiologist
- Department of Cardiology
- Kerala Institute of Medical Sciences
- Thiruvananthapuram, Kerala, India
- Itzhak Kronzon MD FASE FACC FACP FESC FAHA
- Chief, Cardiac Imaging
- Professor of Cardiology
- Lenox Hill Heart and Vascular Institute
- of New York
- Hofstra University—NSLIJ School of
- Medicine
- New York, USA
- Jagdish C Mohan MD DM FASE
- Director of Cardiac Sciences Department of Cardiac Sciences
- Fortis Hospital
- Shalimar Bagh, New Delhi, India
- Karima Addetia MD FRCPC
- Clinical Associate of Medicine Department of Medicine
- Section of Cardiology
- University of Chicago
- Chicago, Illinois, USA
- Madhav Swaminathan MD FASE FAHA
- Associate Professor of Anesthesiology Clinical Director, Cardiothoracic
- Anesthesiology and Critical Care
- Medicine
- Duke University Health System Durham, North Carolina, USA
- Manish Bansal MD DNB (Cardiology) FACC FASE FISCU
- Senior Consultant Cardiology Medanta—The Medicity
- M Sonia Jain MD MRCP (UK)
- Cardiologist
- Olmsted Medical Center
- Rochester, Minnesota, USA
- Munesh Tomar MBBS MD FNB Associate Director
- Department of Pediatric Cardiology
- and Congenital Heart diseases
- Medanta—The Medicity
- Gurgaon, Haryana, India
- Navin C Nanda MD DSc (Med) (Hon) DSc (Hon) FACC FAHA FISCU (D)
- Distinguished Professor of Medicine and Cardiovascular Disease
- University of Alabama
- Birmingham, Alabama, USA
- Nitin J Burkule MD DM DNB FASE FACC
- Consultant Cardiologist
- Jupiter Hospital
- Thane, Maharashtra, India
- Patrizio Lancellotti MD PhD FESC FACC
- Head
- Intensive Care Cardiology Unit
- University of Liege
- Hospital Center
- Professor
- Clinical Medicine
- University of Liege
- Liege, Belgium
- Qing Zhang MD PhD
- Professor
- Department of Cardiology West China Hospital
- Sichuan University
- Chengdu, Sichuan, China
- Rahul Mehrotra MBBS MD DNB (Cardiology)
- Senior Consultant Cardiology Medanta Heart Institute
- Medanta—The Medicity
- Gurgaon, Haryana, India
- Raj Kumar MD (Physician) PG Diploma in Clinical Cardiology FNIC
- Consultant
- Department of Noninvasive Cardiology Max Superspecialty Hospital
- Saket, New Delhi, India
- Raluca Dulgheru MD
- Cardiologist
- Department of Cardiology Heart Valve Clinic
- University Hospital Sart Tilman
- University of Liege
- Liege, Belgium
- Ram Bedi PhD MBA
- Affiliate Assistant Professor Department of Bioengineering
- University of Washington
- Seattle, Washington, USA
- Ravi R Kasliwal MD DM
- Chairman
- Clinical and Preventive Cardiology Medanta Heart Institute
- Medanta—The Medicity
- Gurgaon, Haryana, India
- Roberto M Lang MD FASE
- Professor
- Department of Medicine and Radiology
- Director
- Noninvasive Cardiac Imaging Laboratories
- Section of Cardiology
- Department of Medicine
- University of Chicago
- Chicago, Illinois, USA
- Roxy Senior MD DM FRCP FESC FACC
- Professor of Clinical Cardiology
- Consultant Cardiologist and Director
- of Echocardiography
- National Heart and Lung Institute
- Imperial College, London
- Royal Brompton Hospital, London
- Consultant Cardiologist and Director of
- Cardiac Research
- Northwick Park Hospital
- Harrow, London, UK
- Sanjay Mittal MD DM (Cardiology)
- Senior Director
- Clinical Cardiology and Research Medanta—The Medicity
- Gurgaon, Haryana, India
- Sanjiv Kaul MD FACC FASE FAHA FESC FRCP (London)
- Ernest C Swigert Endowed Chair in Cardiovascular Medicine
- Professor of Medicine and Radiology
- CEO, Knight Cardiovascular Institute
- Oregon Health and Science University
- Portland, Oregon, USA
- S Baskaran MBBS DNB (Medicine) DNB (Cardiology)
- Senior Registrar Deparment of Cardiology
- Kerala Institute of Medical Sciences
- Thiruvananthapuram, Kerala, India
- Shantanu P Sengupta MD DNB FACC FASE FCCP
- Director
- Sengupta Hospital and Research Institute
- Nagpur, Maharashtra, India
- SK Parashar MD FACC
- Senior Consultant Cardiologist Metro Heart Institute
- New Delhi, India
- Srikanth Sola MD
- Additional Senior Consultant Department of Cardiology
- Sri Sathya Sai Institute of Higher
- Medical Sciences
- Bengaluru, Karnataka, India
- Sudhir Wahi MBBS MD FRACP FCSANZ
- Associate Professor
- Department of Cardiology
- Director of Echocardiography
- Princess Alexandra Hospital
- University of Queensland
- Brisbane, Queensland, Australia
- Sunil Mankad MD FACC FCCP FASE
- Associate Professor of Medicine
- Mayo Clinic College of Medicine
- Associate Director, Cardiology
- Fellowship
- Director, Transesophageal Echocardiography
- Board of Directors, American Society of
- Echocardiography
- Ty Whitfield MD
- Cardiovascular Diseases Fellow Department of Medicine
- Division of Cardiovascular Diseases
- University of Alabama
- Birmingham, Alabama, USA
- Vinayak Agrawal MD DNB (Cardiology) FACC FASE
- Senior Consultant Department of Cardiology
- Medanta—The Medicity
- Gurgaon, Haryana, India
- Vishwas Mohan MBBS Dip Card (UK) Attending Cardiologist
- Primus Hospital
- Chanakyapuri, New Delhi, India
- Vivek Jain MD Physican PGDCC Senior Resident
- Medanta—The Medicity
- Gurgaon, Haryana, India
- Yu-Jia Liang PhD MD
- Associate Professor Department of Cardiology
- West China Hospital of Sichuan
- University
It gives me immense pleasure to write the foreword for the book Applied Echocardiography in Coronary Artery Disease. Having known Dr Kasliwal for over three decades now, I should say a work like this, with internationally renowned faculty and some of the best known Indian authors, was long overdue! This book fulfills a hiatus that existed in our practical understanding of patients of coronary artery disease: from the outpatient clinics to the emergency room and from the critically ill patients in the ICU to the cardiac operation theater.
As a cardiac surgeon, I have been witness, as well as a part, of the stupendous growth echocardiography has achieved during the past decades. I remember vividly the pioneering work of Drs Kronzon and Kasliwal in evaluation of protruding atheromas of the aortic arch not so far back and here we are, in an era wherein the use of 3D technology for mitral valve repair has become commonplace in the operation theaters across the globe.
As coronary artery disease constitutes the largest number of patients in any cardiac department, echocardiography has emerged as a key investigation, something that is truly indispensable. However, echocardiography needs to be viewed in clinical context and therein lies the true significance of this book—from scientific thinking to practical demonstration for clinical decision making for the patients.
I unhesitatingly recommend this text to everyone who is interested in learning the nuance of echocardiography. My colleague Ravi Kasliwal and the “who's-who” of the world of echocardiography who have contributed to this book, deserve my appreciation.
Naresh Trehan
Diplomate American Board of Cardiothoracic Surgery
Chairman and Managing Director, and
Chief Cardiac Surgeon
Medanta—The Medicity
13Foreword
It is my pleasure and honor to write a few words about my Indian colleagues and the current edition of the Applied Echocardiography in Coronary Artery Disease. Indian cardiologists have always been an example for the rest of the world in the field of echocardiography, with dynamic pioneers and innovative specialists of this fantastic technique. More important, facing such an important clinical problem as ischemic heart disease, we need to be not only echocardiographists, but also clinicians, that means doctors able to integrate the echocardiographic results in their clinical context, and to use these results to give the best therapy to the patient. Several echocardiographic techniques, including 2D, 3D echocardiography, stress echocardiography, contrast echocardiography and other more recent techniques such as tissue Doppler imaging and deformation imaging, are perfectly described in this book, and their use in ischemic heart disease is clearly depicted.
In that way, Applied Echocardiography in Coronary Artery Disease is the perfect example of what we can expect from a medical book: to be complete, exhaustive, comprehensive, but also easy to use in clinical practice by all practicing physicians. The result is here: this book will be an easy and fantastic tool for all Indian cardiologists, and probably around the world.
This foreword is also the opportunity for me to underline the strong and friendly relationship between Indian and European echocardiographists. As a specialist of echocardiography, but also President of the European Association of Cardiovascular Imaging, I am happy to see that in this book, the patient is at the center, and all the efforts are done to use echocardiography to find the best way to treat him/her.
The next step will be multimodality imaging. Other imaging techniques are also useful for the assessment of coronary artery disease. I am sure that the next objective of the authors will be to teach us how and when to use echocardiography and other imaging techniques in different clinical scenarios.
At the moment, we are learning echocardiography. Enjoy the Applied Echocardiography in Coronary Artery Disease!
Gilbert Habib
President European Association of
Cardiovascular Imaging (EACVI)
Head
Department of Cardiology
University Hospital of Timone
15Preface
Coronary artery disease (CAD) is one of the leading causes of death worldwide, and its prevalence continues to increase in many parts of the world. The patients of CAD thus constitute a major chunk of the patients seen by cardiologists today. For optimal management of these patients, the cardiologists rely on a thorough clinical evaluation supplemented by appropriate investigations. Echocardiography is one of the most useful imaging modalities available for this purpose in these patients.
Echocardiography is noninvasive, versatile, and safe and provides a vast amount of information about cardiac structure and function almost instantly. With its various modalities encompassing the entire spectrum of CAD—from visualization of early evidence of atherosclerosis to assessment of myocardial ischemia and viability to guiding therapeutic interventions—echocardiography assists at every step in critical decision making in these patients. For example, in a patient with CAD slated to undergo percutaneous coronary intervention, detection of significant mitral regurgitation will alter the entire course of treatment. Hence, a clinician dealing with the patients of CAD today cannot afford to be ignorant of the various aspects of echocardiography and the implications thereof.
Elaborate texts have been written and a huge amount of information is available about various aspects of echocardiography, both in the print form and on the internet. These are mainly textbooks of echocardiography describing the techniques and the role of echocardiography in all forms of cardiovascular diseases. However, the vastness of the available literature means that very often the interested reader has to sift through volumes of material on the subject and is left bewildered at the end of it all. This is the very need that the book aims to fulfill by compiling the state-of-the-art and updated knowledge about the role of echocardiography in the evaluation and management of patients with the various facets of CAD. When confronted with a patient of CAD and assailed with doubts regarding any aspect, the practicing physician needs to just pick-up this book and find the solution!
The book is divided into two sections—the first section deals with the technical aspects of the commonly used echocardiographic modalities while the second section discusses the clinical application of these modalities in the evaluation of patients with CAD. The contributors are the respected and renowned names in the field of echocardiography with years of experience behind them. They have graciously spent time and energy to give their best for this book. My grateful thanks to all of them for having responded to my numerous emails and conceding to my demands elegantly.
I hope the book will be widely read and will satisfy the needs of the discerning physicians!
17Acknowledgments
I am extremely thankful to Shri Jitendar P Vij (Group Chairman), Mr Ankit Vij (Group President), Mr Tarun Duneja (Director-Publishing), Mr KK Raman (Production Manager), as well as the editorial team of Mr Sarvesh Singh, Mr Mohit Bhargava, Mr Pramod Rout (Typesetter), Mr Amit Mathur (Graphic Designer) and Ms Monika Arora of M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, for all their efforts and support in bringing out our ideas in print form.18