Second Edition
Ashfaq UI
Hassan
MBBS MS
Consultant Anatomy
SKIMS Medical College
Bemina, Srinagar,
Jammu and Kashmir,
India
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USMLE Step 2 CK Platinum Notes
First Edition: 2013
Second Edition: 2016
9789352501724
Printed at
fm3Contributors
Ashfaq UI Hassan
MBBS MS
Consultant–Anatomy
SKIMS Medical College
Bemina, Srinagar, Jammu and Kashmir, India
Prof. Showkat A Zargar
MD DM (Gastroenterology)
Director and Principal
Sher-i-Kashmir Institute of Medical Sciences (SKIMS)
Srinagar, Jammu and Kashmir, India
Prof. Naseer Mir
MS (Orthopedics)
Professor and Head – Orthopedics
Sher-i-Kashmir Institute of Medical Sciences (SKIMS)
Srinagar, Jammu and Kashmir, India
Dr Sheikh Manzoor Ahamed
MD (Dermatology)
Associate Professor and Head–Dermatology
Sher-i-Kashmir Institute of Medical Sciences (SKIMS)
Srinagar, Jammu and Kashmir, India
fm5Preface to the Second Edition
I am extremely obliged to the Almighty Allah and no words would be enough to express my thanks to his holiness for guiding me.
This book USMLE Step 2 CK Platinum Notes consists of complete revision material for the preparation of the USMLE examinations with important latest questions asked in these examinations and most of the students do not fare well with these questions, thus significantly lowering their scores.
The book is for complete revision with special focus on the most common and most important cases asked. It covers special and important topics which are most frequently asked by the examiners.
The prime focus for the students to go through the most important points and recapitulating these at the end is important for any examination and special focus for the same has been given for their benefit.
Like the other series of books for the USMLE examinations being authored by me, which have had a tremendous success, I hope this effort of mine again would be helpful for the students throughout the world in their pursuit of academic excellence along with the important fact of getting a very good score in the examinations.
I hope the book proves to be useful for our students to the fullest.
I would encourage any aspiring student to join me for his/her contribution.
Ashfaq Ul Hassan
fm7Preface to the First Edition
It gives me a great pleasure to introduce Platinum Notes for USMLE Step 1 and Step 2.
A need was felt by most of the students for a comprehensive book for USMLE for preparing extensively and simultaneously getting a very good score.
My efforts are directed to benefit the students to the maximum.
For a student preparing, revising, forgetting and consulting different books is a part of the game. In this journey some students tend to get nervous and anxious and I thought of putting all my best efforts into one book which would make the preparation simpler, interesting, more lucid and palatable.
High yield points, important topics, clinical correlations, in-depth focus on subjects, easy retention and quick revision are the points on which I have focused taking into account the latest trends of the examinations.
The matter in the book is highly concentrated, needs multiple revisions and deep concentration for retention.
The book has been framed to simulate the study pattern of USMLE examinations to its best.
The questions in the text and after every subject are almost similar to the questions put in the actual USMLE examination which gives a student a good chance to understand the standard of USMLE as well as to prepare for the examinations in a better way.
I feel that the students would be benefitted through my effort and a feedback from the students would be highly appreciated at ashhassan@rediffmail.com
I wish you good luck for your academic pursuits.
Ashfaq Ul Hassan
fm9Acknowledgments
No words would be enough to express my regards to Prof. Showkat A Zargar, Director, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Jammu and Kashmir, India for his constant encouragement.
I am also thankful to my father Prof. Ghulam Hassan for his constant encouragement in all my academic pursuits and guiding me throughout the process of the completion of this book.
I convey my sincere thanks to Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India for their efforts and suggestions, especially Shri Jitendar P Vij (Group Chairman), Ms Chetna Vohra (Associate Director), and Ms Payal Bharti (Project Manager) for helping me through my idea.
fm11Abbreviations
1°Primary
2°Secondary
#Fracture
ACEAngiotensin converting enzyme
ACE-IAngiotensin converting enzyme inhibitor
ACTHAdrenocorticotropic hormone
AChAcetylcholine
AdrAdrenaline
ADAutosomal dominant
ADHAnti-diuretic hormone
AFAtrial fibrillation
AFBAcid-fast bacilli
AFPAlpha-fetoprotein
A.k.aAlso known as
ALLAcute lymphocytic leukemia
AMLAcute myelogenous leukemia
ANAAntinuclear antibody
ANSAutonomic nervous system
APAnteroposterior
ARAutosomal recessive
ARDSAcute respiratory distress syndrome
ARFAcute renal failure
ASAortic stenosis
ATPAdenosine triphosphate
ASDAtrial septal defect
AVAtrioventricular
A/EAll except
Acc/ toAccording to
Ad/E, ad/eAdverse effects
A/W or a/wAssociated with
BBBBundle branch block
bidTwice a day
BMRBasal metabolic rate
BPBlood pressure
BPHBenign prostatic hypertrophy
BUNBlood urea nitrogen
B/LBilateral
BMBone marrow, basement membrane
b/n or b/wBetween
C/SCulture and sensitivity
Ca2+Calcium
CABGCoronary artery bypass graft
CADCoronary artery disease
CCFCongestive cardiac failure
CTComputerized tomography
CHFCongestive heart failure
CHOCarbohydrate
CMLChronic myelogenous leukemia
CMVCytomegalovirus
CNCranial nerves
CNSCentral nervous system
COCardiac output
C/OComplaining of
COLDChronic obstructive lung disease
COPDChronic obstructive pulmonary disease
CPKCreatine phosphokinase
CRFChronic renal failure
CRPC-reactive protein
CSFCerebrospinal fluid
CVACerebrovascular accident
CVPCentral venous pressure
CVSCardiovascular system
fm12CXRChest X-ray
CaCarcinoma/Cancer
C/cComplication
CTChemotherapy
C/IContraindication
CI/fClinical features
CTDConnective tissue disease
Cont./LContralateral
CxCervix
D and CDilation and curettage
DIDiabetes insipidus
DICDisseminated intravascular coagulopathy
DIPDistal interphalangeal joint
DKADiabetic ketoacidosis
dLDeciliter
DMDiabetes mellitus
DTRDeep tendon reflexes
DVTDeep venous thrombosis
d/toDue to
D/gDiagnosis
DOCDrug of choice
Ds, d/sDisease, disease
DMDiabetes mellitus
ECGElectrocardiogram
ECTElectroconvulsive therapy
ECHOEchocardiography
EMGElectromyogram
EOMExtraocular muscles
ESRErythrocyte sedimentation rate
ERCPEndoscopic retrograde cholangio-Pancreatography
EUAExamination under anesthesia
FBSFasting blood sugar
FEVForced expiratory volume
FFPFresh frozen plasma
FRCFunctional residual capacity
FTTFailure to thrive
FVCForced vital capacity
FAFatty acid
FFAFree fatty acid
GFRGlomerular filtration rate
GHGrowth hormone
GITGastrointestinal tract
GTTGlucose tolerance test
GUGenitourinary
HAVHepatitis A virus
HCGHuman chorionic gonadotropin
HDLHigh density lipoprotein
HbHemoglobin
HIVHuman immunodeficiency virus
HLAHistocompatibility locus antigen
H/OHistory of
HRHeart rate
HSVHerpes simplex virus
HTNHypertension
HSHereditary spherocytosis
HCCHepato cellular carcinoma
HDHodgkin's disease
I and DIncision and drainage
IDDMInsulin dependent diabetes mellitus
IgImmunoglobulin
IMIntramuscular
INRInternational normalized ratio
ITPIdiopathic thrombocytopenic purpura
IVIntravenous
IVPIntravenous pyelogram
IVUIntravenous urogram
ICTIntracranial tension
IOCInvestigation of choice
ILDInterstitial lung disease
IOTIntraocular tension
Ipsi/LIpsilateral
fm13JVPJugular venous pressure
K+Potassium
K/asKnown as
LAELeft atrial enlargement
LBBBLeft bundle branch block
LDHLactate dehydrogenase
LMNLower motor neuron
LELupus erythematosus
LPLumbar puncture
LVLeft ventricle
LVHLeft ventricular hypertrophy
LNLymph node
MAOMonoamine oxidase
MENMultiple endocrine neoplasia
MIMyocardial infarction or mitral insufficiency
mLMilliliter
MMRMeasles, mumps, rubella
MRIMagnetic resonance imaging
MRSAMethicillin resistant staph aureus
MGMyasthenia gravis
Mc or MCMost common
MNMalnutrition
M/mManagement
Ms, m/sMuscle
NaSodium
NIDDMNon-insulin dependent diabetes mellitus
NSAIDNon-steroidal anti-inflammatory drugs
n.or nvNerve
NHLNon-Hodgkin's lymphoma
OCGOral cholecystogram
PAPosteroanterior
PDAPatent ductus arteriosus
PMNPolymorphonuclear leukocyte (neutrophil)
PPPatient profile
PTProthrombin time, or physical therapy
PTCAPercutaenous transluminal coronary angioplasty
PTHParathyroid hormone
PTTPartial thromboplastin time
P/gPrognosis
PxProphylaxis
PBCPrimary bilary cirrhosis
RARheumatoid arthritis
RBBBRight bundle branch block
RBCRed blood cell
RIARadioimmunoassay
RNARibonucleic acid
RTARenal tubular acidosis
RVHRight ventricular hypertrophy
RxTreatment
R, or T/tTreatment
RTRadiotherapy
SBESubacute bacterial endocarditis
SGOTSerum glutamic-oxaloacetic transaminase
SGPTSerum glutamic-pyruvic transaminase
SIADHSyndrome of inappropriate antidiuretic hormone
SLESystemic lupus erythematous
SCLCSmall cell lung carcinoma
SMSmooth muscle
Supf.Superficial
SqCCSquamous cell carcinoma
TIBCTotal iron binding capacity
tidThree times a day
TSHThyroid stimulating hormone
TTThrombin time
TTPThrombotic thrombocytopenic purpura
TURPTransurethral resection of prostate
TOCTreatment of choice
UCUlcerative colitis
fm14UMNUpper motor neuron
URIUpper respiratory infection
US, U/SUltrasound
UTIUrinary tract infection
UVAUltraviolet A light
U/LUnilateral
VFVentricular fibrillation
VDRLVenereal disease research laboratory (test for syphilis)
V/QVentrilation-perfusion
VTVentricular tachycardia
vWDvon Willebrand's virus
VZVVaricella zoster virus
V/sVessel
VsVersus (= against)
WBCWhite blood cell
WPWWolff-Parkinson-White
WGWegner's granulomatosis
WTWilm's tumor
XLRX linked recessive
YrYear
ZnZinc
ZESZollinger Ellison Syndrome
—Reaction block by, inhibited by
~Denotes heading
!Increase