A
Abortion, spontaneous 180
of abdomen 252f
of axillae 247f
of dorsum of feet 252f
of knee 251f
of neck 247f
of wrist 250f
with skin tag 253f
Acanthosis with skin tags 253f
Acarbose 55
Acrochordons 248
Adipocytes, types of 11
Adipocytic capacitance 11
Adiponectin 152
Adipose atrophy 215
Adverse cardio cerebrovascular event, major 270
AKT2 mutation 220
Alanine transaminase 177
Albiglitude 57
All-cause mortality 267
Alogliptin 56
Ambulatory continuous glucose monitoring 190
American Association of Clinical
Endocrinologists 22
American Association of Diabetes Educators 58
American Geriatrics Society 59
Aminoglycosides 129
Anemia 88
Angina, unstable 268
Angioplasty plus stents 111
Ankle-brachial index 108
Anticholinesterase 169
Antioxidant activity 158
Antioxidant defenses 154
Antiplatelets 265
Antivascular endothelial growth factor 61
Apgar score 192
Apolipoprotein C3 151
Arterial revascularization therapy study 271
Artery bypass graft 269
Arthrosis 107
Artificial pancreas 41
Asymptomatic bacteriuria 125
Atherosclerosis, pathogenesis of 263
Athlete's foot 236
Atrophy, local 222
Autonomic neuropathy 119
B
Bacteremia 133
Bacteriology cultures 99
Barbiturates 227
Bare metal stent 270
Bariatric procedures 158
Barium studies 168
Barraquer-Simons syndrome 222
Basal rate infusions 36
Berardinelli-Seip syndrome 217
Bethanechol 169
Bionic pancreas 41
Birth trauma 192
Blocks inhibitory D2 receptor 169
Blood glucose
for fasting 191
monitoring, punctures in fingers from 257f
postprandial monitoring of 190
Blood urea nitrogen 109
Body weight 9
Borderline perfusion 113
Botulinum toxin 170
Breath tests 168
Breech presentation 194
Brittle diabetes 40
Buffalo hump 221f
Bypass angioplasty revascularization
investigation trial 269
C
C3 nephritic factor 221
Calcium channel blocker 146
Candidiasis 232
Carbuncle 131
Cardiac anomalies, congenital 193
Cardiovascular death 267
Cardiovascular risk factors 106
Cardiovascular safety 22
Cardiovascular studies 144
Carpenter-Coustan criteria 187
Cataract 75
Cathy Kim image 196f
Cell-mediated immunity 117
Cellular injury 156
Cephalosporins 129
Cerebral arteries 113
Cerebrovascular accidents 113
Cesarean delivery 185
Chambers 112
Charcot's disease 104
Charcot's foot 100
Charcot's neuroarthropathy 98f
Childhood obesity 189
Childhood Z-scores 189
Chloroquine 212
Cholecystitis 127
Cilostazol 110
Cisapride 169
Clindamycin 129
Clinical research network system 157
Clostridium hystoliticum 229
Clostridium perfringens 127
Clostridium welchii 127
Cockcroft-Gault equation 82
Colon 165
Combination therapy 22
Complete blood count 177
Congenital malformations 171
Conjunction 189
Cord C-peptide 185
Cornea 74
Coronary artery
bypass surgery 270
revascularization of 269
left anterior descending 272
unprotected left main 270
Coronary by-pass 214f
Coronary physiology 272
Cotton wool spots 63
Creatinine 109
Cunninghamella species 132
Cushing's syndrome 172
Cystitis 125
Cytokines 155
D
Dapagliflozin 56
Deep tendon reflexes 98
Degludec insulin 267
Deoxyfructosyl 33
Depot steroids 221
Dermatomyositis 227
and pregnancy 171
epidemiology 173
atypical clinical presentation of 47b
classification 1
comorbidities of 47
control
cardiovascular risk in 85
education 193
effects of 123
interventions and complications,
long-term 91
management of infections in 135
nonretinal complications of 74
pathophysiology of 46
revascularization in 271
reverse 6
skin
traditional complications of 47
pathogenesis of 9f
vascular complications of 29
cardiovascular of 264
diagnosis of 1
effects of 122
tuberculosis on 124
gastrointestinal complications of 164
incidence in 241b
increased incidence in 241
risk of 181
Diabetic bulla 229
Diabetic cataracts, reversible 75
Diabetic complications, development of 143
Diabetic dermopathy 213
Diabetic factor consists 92
advantages 101t
antibiotic treatment 102
disadvantages 101t
general treatment 101
infections 128f
bacteriology of 92b
local treatment 101
pathogenic factors of 104fc
prevention 91b
management of acute 99
treatment 101
Diabetic ketoacidosis, recurrent 40
Diarrhea 170
Dietary approaches to stop hypertension diet 147
Digital sclerosis 225
Domperidone 169
Dopamine D2 blockers 169
Doppler 108
Dorsum of hand, psoriatic plaques on 256f
Drowsiness 169
Drug eluting stent 270
Dual-energy X-ray absorptiometry 192
Dulaglutide 57
Dunnigan's congenital partial lipoatrophy 221f
Dunnigan's syndrome 220
Dyspepsia 170
Dystrophic nails 224f
E
Edema 158
Elbow, psoriatic lesions of 255f
Electrocardiogram 177
Electrogastrography 168
Elevated protein kinase C 117
Empagliflozin 56
End stage kidney disease 79
Endocrinopathies, manifestation of 172
Endoplasmic reticulum 154
Endotoxins 155
Enteroviruses 127
Epilepsy 227
Eplerenone 147
Esophageal dysmotility 165
Esophageal motility disorder 165
Esophagus 165
European Medicines Agency 263
Extensor tendons of feet, retraction of 230f
Extrapyramidal syndromes 169
Eyelids, skin tags in 219f
F
Fasting and pre-meal glucose 51
Fasting insulin 189
Fatal myocardial infarction 267
Fatal stroke 268
Fatty infiltration 216
Fatty liver 218
Fertility and contraception 175
Fetal cardiac hypertrophy 193
Fetal demise 180
Fetal echocardiogram, importance of 193
Fetal heart rate monitoring, continuous 180
Fetal hemoglobin 31
Fetal monitoring during labor, continuous 194
Fetal viability 193
Fibric acid medications 183
Fibrous proliferation 64
Flatbush diabetes 15
Flexion tenosynovitis 225
Flexor Babinski's response 98
Flexor tenosynovitis 230f
Fluconazole 165
Frameshift mutations 151
Free fatty acid delivery 152
Fructosamine 32
Full-thickness retinal hole formation 70
Fungal cystitis 132
G
Gamma-glutamyl transferase 156
Gangrene 111
Gangrenous complications, cause of 108
Gangrenous tissues 95
Gastric bypass 158
Gastric emptying, scintigraphic
documentation of 168t
Gastrointestinal infections 126
Gastrointestinal system 164
Genetically diverse syndromes 172
Genetics 11
Genitourinary infections 124
Genitourinary tract infections 124
Gestational diabetes
diagnosis of 184
Ghrelin agonists 169
Glaucoma 74
Gliclazide 20
Glimepiride 20
Glipizide 20
Glucagon-like peptide 266
Glulisine 178
Glycated hemoglobin level 142
Glycation, chronic 92
Glycemic goals and goal setting 51
Glycemic status, monitoring of 32
Glycemic targets 171
Glycemic variability 116
Glycohemoglobin 2
Glycosuria 235
Gynecomastia 169
H
Head and neck infections 119
Headache 170
Hemolytic anemia 218
Hepatobiliary infections 126
Hepatocellular carcinoma 156
Hereditary hemochromatosis 258f
High performance liquid chromatography 30
Hirsutism 218
Hydrogen peroxide 154
Hydrolytic enzymes 151
Hydroxychloroquine 212
Hydroxyl 154
Hyperinsulinemia 215
Hyperlipidemia, severe 230
Hyperparathyroidism 88
Hypertensive hemorrhages 113
Hypertrophy, local 222
Hypoadiponectinemia 155
Hypoaldosterone renal tubular acidosis 148
Hypoglutathionemia 155
Hyporenin 148
Hypothenar areas of palms, puncture
marks in 257f
I
Indian Diabetes Risk Score 157
Inflammation 155
Inflammatory cells 152
Influenza 124
Inguinal intertrigo 234f
delivery 36
hematomas 238f
chronic 221
site acanthosis 238f
areas of 239f
lipohypertrophy 240f
in thighs 240f
pump 35
advantages of 40
disadvantages of 40
purification of 221
receptor substrate phosphorylation 152
clinical components of 12f
severe 39
severe 215
signaling 127
Integrated glucometer and remote control 38
Intensive neonatal care 186
Intergluteal intertrigo 234f
International Clinical Diabetic Retinopathy and
Diabetic Macular Edema Scale 66t
International Diabetes Federation 58
International Federation of Clinical Chemistry
Reference Measurement Procedure 30
International Federation of Gynecology and
Obstetrics 186
International Verapamil SR-Trandolapril Study 142
Interstitial cells 166
Interstitial fluid 190
Iris 74
Islet cell dysfunction 11
Itopride 169
K
lesions in wrist, classical 259f
with beefy lesions in wrist, classical 259f
with lesions in toes, classical 259f
Ketonemia 180
development of 83
Köbberling syndrome 220
Kobner reaction 255
L
Labor and delivery 194
Large for gestational age 180
Latent autoimmune diabetes 15
Latent infection 122
Lawrence syndrome 218
Lens 75
Leukotrichia 245f
Levosulpiride 169
Levothyroxine 194
Linagliptin 56
Lipid accumulation 211f
Lipoatrophic diabetes 220f
acquired generalized 219f
congenital 217f
phlebomegaly in 223f
with muscle hypertrophy 219f
with phlebomegaly 220f
Lipoatrophy 209
Lipodermatosclerosis 114
Lipohypertrophy in abdomen 239f
Lipoidica 210
Lipoproteins, circulating 150
Lipotoxicity 215
Lixisenatide 267
Low birth weight 11
Lower blood pressures 144
Lower limb amputations 112
Lymphocytes, effects on 118
M
Macrovascular complications 126
Macula 70
Male genitalia 129
Maturity onset diabetes of young 15
Mean plasma glucose 29
Melanin pigmentation 213
Metabolic dysfunction 189
Metabolic pathway, effects on 116
Metabolic rate, increased 218
Metacarpophalangeal joints 226f
Metatarsophalangeal joint, first 94f
Methicillin-resistant Staphylococcus aureus 128
Metoclopramide 169
Metronidazole 129
Microaneurysms 63
Microsomes 154
Microvascular angina 263
Microvascular disease 263
Miglitol 55
Mitochondrial deoxyribonucleic acid 154
Mitochondrial oxidative 110
Monitoring glycemic control 29
Monooxygenases 154
Mosapride 169
Motilin receptor agonists 169
Mucor 132
Multiple daily injections 178
Muscarinic agonist 169
Mycobacterium tuberculosis 122
Myofibroblastic phenotype 155
N
Naftidrofuryl 110
Nail dystrophy, improvement in 225f
Nails in psoriasis, pitting of 256f
Nateglinide 55
National Glycohemoglobin Standardization
Program 30
National Institute of Diabetes and Digestive and Kidney Diseases 156
National Institutes of Health 186
complicated with
infection 213f
ulcerations 213f
in initial stages 210f
with infected ulcerations 213f
Necroinflammation 156
Necrotic toe 260f
Neonatal intensive care unit 192
Neostigmine 169
Neovascularization 64
Nephrology 88
Nerve palsy 74
Neurological examination 97
Neutrophils, effects on 118
Newer antidiabetic drugs 266t
Niacin 183
Non-adipocytic cells 11
Non-enzymatic glycation 225
Non-traumatic amputations 269
Nutrition 193
O
Olmesartan 143
Omega-3 fatty acids 183
Onycholysis in psoriasis 256f
Onychomycosis 236
Oral agents, classification of 16
Oral and esophageal candidiasis 131
Osteomyelitis 103
P
Palmar fascia fibromatosis 225
Palpable petechiae 112
Paracrystalline inclusions 153
Parafoveal capillaries, nonperfusion of 70
Paranasal sinuses 134f
Parathyroid hormone 88
Particular muscular group 107
Pedis foot 236
Penicillin 129
Percutaneous coronary intervention 270
Percutaneous transluminal coronary
angioplasty 270
Perilipin-1 gene 151
Perimuscular fat and phlebomegaly, loss of 220f
Perinephric abscesses 126
Periorificial vitiligo 244f
Peripheral arterial disease 106
Pharmacotherapy 53
Phenytoin 227
Phytobezoars 167
Placental insufficiency, markers of 193
Plantar subcutaneous tissue, decreased 97
Pneumonia 124
Polyhydramnios 181
Polyol pathway shunting 117
Polyuria 46
Poor glycemic control 181
Postpartum period medical management 195
Postreceptor insulin signaling 174
PPARG mutation 220
Preconception insulin resistance 174
Preconception period medical nutrition
therapy 176
Prediabetes 4
Prenatal care 193
Prenatal vitamin supplementation 172
Profibrogenic cytokines like interleukin-10 152
Proinflammatory cytokine secretion 155
Prokinetics 167
Protein carbonyl content 154
Proteus 125
Protruding interphalangeal joint 95f
Prucalopride 169
Pseudomonas aeruginosa 120
Psoralen, local 212
Psoriatic arthritis, acute 255f
Pump delivers insulin 36
Pyloromyotomy, endoscopic 170
Pyloroplasty, surgical 170
R
Radiological manifestations, effects on 122
Radionuclide gastric emptying scintigraphy 168
Radionuclide scanning 120
Ramadan fasting 40
Randomized controlled trial 38
Red blood cells 31
Renal disease 182
Renal failure, chronic 97
Repaglinide 55
Respiratory tract infections 121
Resting pain, treatment of 111
Rheumatoid arthritis 218
Rifampicin 124
Rosiglitazone 55
S
Salmonella enteritidis 127
Saxagliptin 56
Scatter laser photocoagulation 71
Secretion of anti-inflammatory cytokines 152
Sedimentation rate 109
Self-monitoring programs 59
Sensor augmented pump therapy 37
Serum leptin levels, low 218
Several cardiometabolic risk factors 150
Severe neonatal hypoglycemia, prevalence of 192
Shin spots 213
Signaling pathway, effects on 116
Simple steatosis 156
Sirolimus eluting stent 270
Sitagliptin 56
Skin
and skin lines, blanching of 228f
bacterial infections of 236
candidiasis 236
diffuse darkening of 258f
dryness 236
in center, atrophy of 212f
infection 128
irritation 94
thinness 236
Small dense low-density lipoprotein 154
Small for gestational age 181
Small intestinal bacterial overgrowth 165
Smartguard insulin pump 38f
Smartguard technology 37
Soft exudates 63
Soft tissue infection 128
Sphygmomanometer 140
Spironolactone 147
Sputum positivity 122
Staphylococcus aureus 102
Staphylococcus-resistant 102
Stasis dermatitis 236
Statin 183
Stellate cells 155
Stenosing tenosynovitis 92
Sterol regulatory element-binding proteins 153
Stomach 165
Subcutaneous arterioles 260
Subcutaneous skin 214
Submammary skin tags, multiple 254f
Superoxide 154
Suppress liver inflammation 155
T
Therapy, cost-effectiveness of 24
Thiobarbituric acid reactive substances 154
Thrombophlebitis 170
Thrombosis, local 113
Tight glycemic control 179
Toes 92
Transcutaneous oxygen measurements 109
Transient ischemic attacks 113
Transpyloric stent placement 170
Triglycerides 189
Truncal obesity 9
Truven health marketscan database 173
Two-hit hypothesis 152
U
Ulcer 128
United States Joint National Committee 144
Unstable angina, significance of 268
Urine albumin level 82b
US Food and Drug Administration 263
V
Vascular examination 99
Venous ulcers 114
Verrucous’ appearance 251f
Vibratory sensation 97
Visceral adipose tissue 152
elbow on 243f
in dorsum of hands and fingers 243f
of glands and prepuce 247f
of nipple 246f
of penis 246f
of scrotum 246f
of surgical scar 244f
on dorsum of feet 244f
on knees 243f
over anterior neck 245f
over arm and forearm 245f
with well-delineated borders 242f
typical lesions of 242f
Voracious appetite 218