A
Acellular regenerative tissue scaffold 160
Aching 40
Acid glycerol lysis test 110
Acid-fast bacilli, multiple 106f
Acne 80
Activated partial thromboplastin time 108
Adalimumab 83
Alcohol 29
Allergic contact dermatitis 91
Allergic diathesis 43
Allograft 160
Amorphous hydrogel 132
Anakinra 83
Anaphylactic shock 44
Angiogram 104
Angiotensin-converting enzyme 110
Antibacterial agents 53
Antiembolism stockings 127
Antiglomerular basement membrane 103
Anti-infectives, use of 52
Anti-inflammatory action 163
Antimicrobial photodynamic therapy 162
Antineutrophilic cytoplasmic autoantibody 104
Antioxidant agent 26
Antiphospholipid syndrome 68
Antiseptic 41
Antistreptolysin O titers 103
Aortic coarctation 68
Aorto-bifemoral bypass 78
Arm-foot venous pressure 96
Arterial brachial pressure index 128
Arteriosclerosis obliterans 68
Artery 34
Asthma 43
Atherectomy 79
Atmospheres absolute 163
Auscultation 34
Autoamputation 29
Autolytic debridement 89
Autonomic neuropathy 48
Azathioprine 83
B
Bacterial index 105
Bacterial infection, levels of 21f
B-cell lymphoma 17
Becaplermin 76
Bedside tests 31
Bedsores 1
Bicuspid valves 8
Bilayer cellular construct 54
Biochemical profile 74
Bioelectric dressings 164
Bioengineered skin substitutes 116
Biopharmaceutical agents 156
Biopsy 103
Bony prominences 50
Bowel bypass syndrome 29
Boyd's perforators 10
Buerger's angle 34
Buerger's disease 138
Bullous diseases 16
Bullous pemphigoid 110
Bullous pyoderma gangrenosum 81f
Bullous vasculitis 15f
C
Cadaveric allografts from skin bank 147
Cadexomer iodine 115
Calf muscle functioning, insufficient 37
Canakinumab 83
Carbon dioxide angiography 102
Cardiovascular system 71
Catheter-based intravascular ultrasound 102
Causative organism 80
Cell cultures 146
Cell mediated immunity, defective 80
Center for disease control and prevention 2
Central nervous system 108
Cerebrovascular accident 71
Charcot fracture 57
Charcot joint 107
Charcot neuroarthropathy 49
Charcot neuropathic osteoarthropathy 50
Charcot's deformity 32
Charcot-Marie-Tooth disease 107
Chilblains 16
Chlamydia 14
Chlorambucil 83
Chlorine 163
Chromate glycerine 42
Churg-Strauss syndrome 85
Cilostazol 123
Clammy extremities 29
Claw toes 63
Clofazimine 83
Colchicine 83
Common femoral artery, color Doppler of right 100f
Compartment syndrome, chronic 73
Complement deficiency 81
Concealed ulcer, stage of 62
Connexins 157
Coombs test 110
Corona phlebectatica 39
Coronary artery disease 29
Cosmetic issues 146
Cosmetically unacceptable linear swellings 28
Cosmetic-spider webs 42
Cough impulse test 31
Creatine phosphokinase 103
Creatinine 99
Cryofibrinogenemia 68
Cryofibrinogens 89
Cryoproteins 15
Cutaneous discoid 16
Cutaneous T-cell 17
Cyclophosphamide 83
Cyclosporine 83
Cysteine proteinase 25
Cytomegalovirus 14
D
Da Vinci vein 6
Dakin's solution 138
D-dimer assays 95
Deep fascial plexus group 9
Deep fungal infections 82
Deep mycotic infections 17
Deformities 65
Dehydrated amniotic membrane allograft 161
Deoxyribonucleic acid 106
Dermal neutrophilia, epidermal necrosis with 16f
Dermal regeneration, scaffold for 156
Dermal tissue 118
Dermatological manifestations 38
Dermis 137
DeWeese's test 34
Diabetic foot 51
disease 47
infection 47
system of 49t
pathology, multifactorial etiology of 48f
physical examination 50
surgery classification 55f
classification systems 51
ulceration, etiology of 47
Diabetic revascularization 57
Diosmine 120
Dorsiflexors, clinical test for 36f
Doxycycline 121
Dragging pain 28
Dry foam 44
Dry skin 62
Duplex Doppler ultrasonography 96
Dyslipidemia 68
Dysproteinemia 17
E
Ecthyma gangrenosum 21
Eczematous pigmented skin 32f
Egyptian eye 8f
Electrocardiogram 103
Electrocardiography 110
Electrolyte 99
Electromyography 103
Embolism, investigations for 102
Emission tomography scans, positive 51
Endocrine disorders 29
Endovascular laser therapy 92
Endovenous ablation 45
Enterobacter 19
Enterococcus 19
Enzymatic debridement 89
Enzyme linked immunosorbent assay 95
Enzyme, topical 54
Eosinophil count, absolute 103
Eosinophilia 103
Epidermal stem cells 24
Epidermal substitutes 117
Epithelializing wounds 134
Epithelioid cell infiltrate 105f
Epithelioma 17
Ergotamine 17
Erysipelas 21
Erythermalgia 16
Erythromelalgia 16
European Society of Vascular Surgeons 69
Exercise therapy 77
Extensor hallucis longus 34
Eye of horus 8f
F
Factitious panniculitis 82
Familial neuropathies 29
Fasciectomy, lateral 164
Fat necrosis 16
Fegan's technique 43
Femoral artery, superficial 79
Fibrinogen 103
Fibrinoid necrosis of vessel wall 15f
Fibrinolytic enhancers 123
Fibroplasia 23
Flattened plantar arch 63
Fontaines classification of critical ischemia 70t
and ankle, perforating veins of 6f
architectural changes in 32
infection 51
perforators 11
pressures 50
reducing pressure on 65
ulcers, surgical management of complicated 66
Fossa ovalis 32f
Frequency-rhythmic electrical modulation system 118
Frostbite 62
Frozen autologous plasma 123
G
Gastrointestinal diseases 29
Gastrointestinal disorders 122
Gelatinases 25
Gelatine 158
General health and nutrition 87
Glucose deficiency 26
Glycation, advanced 26
Gout 109
Graduated compression stockings 127f
Graft, type of 142
Gram's stain 21f
Granular casts 103
Granulating wounds 134
Granulomatosis 85
H
Hair loss 32
Hallux rigidus 63
Halogenoderma 82
Halogens 17
Hammer toes 63
Healthcare, cost of 2
Heart failure, decompensated 128
Hemangioma 16
Hemangiosarcoma 17
Hematoma 145
Hematoproliferative disorders 76
Hemogram, complete 103
Hemosiderin staining 40
Hemostasis 23
Heparin 83
Hepatocyte growth factor 155
Herpes virus 14
Hidradenitis suppurativa 80
Hodgkin disease 17
Holiday ulcers 61
Homocystinuria 109
Horse chestnut extract 42
Horus eye 7
Human leukocyte antigen 16
Human skin equivalents 54
Hyaluronic acid, topical 158
Hydrated polymer dressings 132
Hydrosurgical debridement 64
Hydroxyethylrutosides 122
Hydroxyureum 17
Hypercoagulability 43
Hypercoagulable disorders 17
Hypercoagulable state 68
Hypercoagulable status with embolization 29
Hyperimmunoglobulin E syndrome 81
Hyperlipidemia 29
Hyperoxaluria 109
Hyperthyroidism 42
Hyperviscous state 68
Hypogammaglobinemia 81
Hypostatic ulcer 37
I
Ibroblasts 23
Iliac spine, anterior-superior 34
Iliac vein thrombus, common 95f
Immobility 42
Immunomodulatory activity 163
Impregnated dressings 134
Infected ulcer, investigations in suspected 65b
Infectious diseases 17
Infectious Diseases Society of America classification 49t
Infliximab 83
Infra-inguinal revascularization 78
Innate immunity, aberrant response of 80
Interstitial collagenases 25
Intralesional injection 17
Intravascular ultrasound 102
Intravenous immunoglobulin 83
Iodozyme 162
Iron profile 104
Ischemic arterial ulcers 68
Ischemic leg ulcer, etiology of 68b
Ischemic subcutaneous arteriolosclerosis 75
Itching 40
K
Kaposi sarcoma 17
Keratinocyte 117
cell cultures 147f
growth factor 155
photoactivation, marginal 163
proliferation of 23
Keratosis actinica 16
Kidney transplant 75
Klebsiella 19
Klippel-Trenaunay syndrome 28
Kyrle's disease 29
L
Laboratory screening tests 108
Lactic-co-glycolic acid 163
Leg
acute ischemia of 99
edema, chronic 126
elevation 41
extreme deformity of 128
fracture, history of 37
heaviness of 28
perforators 11
arterial cause of 99
case of 87
nonhealing 1
venous 37
complications of 19
due to antineutrophil cytoplasmic antibody-associated vasculitis 85t
etiology of 13
examination in chronic 28
formation, chronic 69f
in rheumatoid arthritis 84t
indication in 142
infectious causes of 108
investigating atypical 108
investigation for 94
principles of 87
microbiology of 19
microbiota of 19
pathology of 13
radiological diagnosis of 94
systemic therapy of 120
topical therapy for 114
treatment
of chronic 28
of nonhealing 28
Leishmaniasis 17
Leukocytosis 103
Levamisole 121
Lichen planus 16
Light emitted diode 163
Light-based therapy 155
Limb edema 40
Lipedema 16
Lipid carriers, nanostructured 158
Lipid control 77
Lipid nanocarriers 158
Lipid nanoparticles 156
Local therapy 83
Lorenzo Tessari's tourbillon technique 44
Lower limb
eponymous perforators of 10f
lymphatic insufficiency of 126
microcirculation of 5
motor power of 35
motor weakness of 36t
nerve examination 36t
swelling of 28
vessels, anatomical landmark for 34t
Lymphangiosarcoma 17
Lymphangitis 20
Lymphatic obstruction 29
Lymphocytes 24
Lymphosarcoma 17
M
Macrophages 24
Maggot debridement therapy 64
Magnetic resonance venography 95
Malleolar flare 39
Malnutrition 66
Mantoux test 103
Marjolin ulcer 17
Martorell's ulcer 72f
Mass spectroscopy 110
Maturation 141
McConkey agar, culture on 20f
Mechanical blistering disorders 29
Mechanical debridement 89
Medication glucocorticoids 26
Mesalazine 83
Mesher for meshing skin graft 142f
Mesoglycans 123
Metabolic disorders 29
Metastasis 17
Methylprednisone pulse 83
Metronidazole 53
Mezlocillin 83
Microangiopathy theory 37
Microbial culture 65
Microcellular rubber 66
Microhematuria 103
Microthrombotic disease 68
Migraine 43
Minocycline 83
Monoclonal gammopathy 80
Morphological index 105
Motor nerves, involvement of 61
Multidisciplinary team, structure of 58b
Multiglycoside 83
Muscle cramps 28
Mycobacteria, atypical 17
Mycophenolate mofetil 83
Myelodyplasia 80
Myeloproliferative disease 80
Myocardial decompensation 43
Myocardial infarction 71
Myxedema 16
N
Necrosis 88
Necrotic ulcers 134
Necrotizing fasciitis 21
Neonatal human foreskin fibroblasts 118
Neovascularization 141
Neutrophilic dysfunction 80
Neutrophilic infiltration 15f
New endovascular techniques 79
New omental transfer surgery 76
Nicorandil 82
Nitric oxide 15
Nodules 89
Nonmedical support hosiery 127
Nutritional deficiencies 29
O
Open ulcer, stage of 62
Open venous surgery 45
Oral corticosteroid cover 83
Osmotic fragility 110
Oxygenation 88
P
Palpable purpura 89
Pancreatic fat necrosis 16
PAPA syndrome 16
Papillary dermal plexus 5
Paraproteins 15
Paratibial perforators 10
Paravasal injection 17
Patch testing 41
Peak systolic velocity 100
Pegfilgrastim 80
Pemphigoid 16
Percussion test 33
Perforator incompetence, evaluation of 97
Perforator reflux 42
Perforator vein 11
Periarteritis nodosa 16
Periodic acid-Schiff stain 109
Peristomal pyoderma gangrensoum 83
Perniosis 16
Persistent sciatic artery 68
Pes cavus 63
Phagedenisme geometrique 80
Phase-contrast techniques 95
Phenothiazine derivative 163
Phlebography 97
Phlebotonics 122
Phlegmasia cerulea dolens 128
Photodynamic antimicrobial chemotherapy 162
Photodynamic inactivation 162
Photonic technology 163
Photoplethysmography 40
Placing test tube in centrifuge 151f
Plantar ulceration, mechanisms of 62b
Plasma spectrofluorimetry 109
Plasminogen activator inhibitor 123
Platelet rich
preparation of 152fc
treatment with 152f
preparation of 149fc
role of 148
test tube with 149f
Plethysmographic techniques 96
Plethysmography 100
Polar tuberculoid leprosy 105
Polyarteritis nodosa 13
Polyiodinated iodine 42
Polylactic-co-glycolic acid 158
Popliteal entrapment 68
Popliteal vein 9
Porcine small intestine submucosa 54
Porphyria cutanea tarda 109
Post-sclerotherapy compression 44
Potassium iodide 83
Prealbumin levels 104
Precursor of keratin 136
Prednisolone 83
Prednisone 122
Pressure measurement 99
Pressure off-loading 91
Pressure sites 30
Pricking and burning sensation 29
Prolidase deficiency 109
Propylthyuracil 80
Prostacycline analoges 123
Prostaglandin 123
Proteus 19
Prothrombin mutation 37
Prothrombin time 108
Protozoa 13
Provocative tests 34
Pruritus 28
Pseudoclaudication 73
Pseudoepitheliomatous hyperplasia 17
Pseudo-Kaposi sarcoma 17
Pseudoxanthoma elasticum 68
Psoriatic arthritis 80
associations of 80b
classical ulcer of 81f
clinical course of 81t
differential diagnosis of 82b
treatment of 83b
types of 81b
ulcer 166
Pyoderma ulcers 138
Pyogenic arthritis 80
Pyostomatitis vegetans 81
R
Radionuclide scintigraphy 96
Recurrent phlebitis 40
Renal disease 29
Renal disorders 29
Renal insufficiency, chronic 68
Ridley's logarithmic scale 105
Rifampicin 83
Right dressings, selection of 134
Rocker bottom foot 50
S
Saphenous fascia 6f
Saphenous nerve 10
Sarcoma 17
Scarless healing 26
Sclerosis, multiple 108
Sedentary lifestyle 68
Semipermeable film dressing 134
Semmes-Weinstein filaments 34
Sensorimotor neuropathy, peripheral 91
Septic phlebitis 128
Seroma 145
Sevoflurane, topical 162
Sheet hydrogel 132
Sickling test 110
Silver compounds 90
Silver impregnated dressings 133
Simvastatin, topical 161
Single-photon emission computed tomography 51
Skin
and peripheral nerve 104
applied anatomy of 136
around ulcers, examination of 29
autoimmune blistering disorders of 29
changes 32t
condition 71
dryness of 29
irritation 28
layers of 137f
pigmentation 28
regeneration 137
replacement, recent advances in 146
smear microscopy 105
wounds, healing of 27
advantages of 141
contraindications for 140
disadvantages of 141
donor sites for 145f
full-thickness 143
harvest 141
harvesting split 142f
methods of fixing 143
split thickness 136
stages of 141f
storage 145
substitutes, biologically active 159
types 141
advantages of different 142t
disadvantages of 142t
Slit skin smear 104
Sloughy wounds 134
Soleus muscle pump 9
Solid lipid nanoparticles 158
Spider veins 30
Split skin graft, techniques of 142
Spondylitis 80
Standard Doppler examination 96
Staphylococcus epidermidis 163
Stasis eczema 89
Stasis ulcer 37
Stellate scarring 32
Sterilization procedures 160
Stewart-Bluefarb syndrome 16
Stratum corneum 164
Streptococcus pyogenes 17
Streptococcus sanguis 17
Strokes 29
Stromeolysins 25
Subcutaneous plexus group 5
Subepidermal bulla 15f
Submuscular plexus 9
Sudomotor dysfunction 48
Suflamethyoxy pyridazine 83
Sulfapyridine 83
Sulfasalazine 83
Sulodexide 123
Supra-inguinal revascularization 78
Surgery, role of 91
Surgical methods 55
Surgical therapy 164
Swabbed material, culture of 20f
Sweet's syndrome, atypical 82
Syphilis 61
Systemic disease, severe 42
Systemic examination 71
Systemic involvement 87
Systemic therapy 83
T
Tacrolimus 83
Takayasu's disease 80
Tap test 33
Tetracyclines 83
Thalidomide 83
Thermal injuries 62
Threatened ulcer, stage of 62
Throbbing 40
Thrombocytopenia 103
Thrombotic thrombocytopenic purpura 17
Thrombus 95f
Tibia, anterior 30
Timolol maleate 161
Topical regimen, choice of 52
Topical therapy 161
Transcutaneous pressure of oxygen 100
Transesophageal echocardiography 103
Triglycerides 104
Tripterygium wilfordii 83
Tuberculoid leprosy, borderline 105
Tulle dressings 53
U
atypical distribution of 45
biopsy in diagnosis 75t
cause of 30
chronicity of 37
common 138
developments 63
examination 29
formation
sequence of chronic 63fc
stages of 62
gravitational 37
irregular large and deep 31f
ischemic 68
liable 61
local care of 76
management of 63
multiple 81f
neuropathic 88t
of various etiologies 30t
prone 61
size, increased 20
trophic 61
type of 134
vaccination 17
venous 88t
with heavy discharge 83
with purulent discharge 83
Ulcerating pyoderma 21
Ulcerating tumors 17
Ulcerative pyoderma gangrenosum 81
Ulcus rodens 17
Ulcus tropicum 17
Ultrasound machine 96f
University of Texas classification system 51
Unna boot 134
Urinary albuminuria levels 104
Ustekinumab 83
V
Vacuum compression therapy 76
Vacuum therapy 54
Valsalva, junction on 96f
Valves 8
Valvular incompetence 13
Valvular system of superficial veins 8f
Varicography 97
Varicose ulcer 37
complication 42
during pregnancy 128
early 128
emptying of 33
gross 128
interventional treatment of 126
of medium severity 128
superficial 128
uncomplicated 126
Vascular insufficiency 48
Vascular tumors, primary 68
Vasculopathy 17f
Venae comitantes 9
Venereal disease research laboratory test 107
Venous sinuses 9
Venous system, superficial 5
Venous thromboembolism, prevention of 126
Venulectasia vein 44
von Kossa stain 109
W
Wagner and Texas classification systems 51t
Wagner classification 51
Wagner method 51
Waldenstrom disease 110
Wave Doppler ultrasonography 96
Wearing footwear 29
White blood cells 14
Wound 51
bed, optimization of 138
chronic 26
cleansing 88
closure with healing 63
contraction 146
impregnated 133
transparent 132
edge of 114
mechanism of delayed 21f
infected 134
management 64
of leg, chronic 13
ready for skin grafting 140f
strength 27
types of 134t
Wound-related factors 134