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Salivary Gland Pathologies
Nisheet Anant Agni, Rajiv Mukund Borle
CHAPTER 1:
Introduction
CHAPTER 2:
Embryological development
CHAPTER 3:
Applied surgical anatomy
Parotid gland
Extent of the gland (Figure 3.1)
Capsule
Gland morphology (Figure 3.2)
Parotid duct
Relations of the gland7 (Figure 3.2)
Structures traversing the gland (Figure 3.2)
Blood supply, lymphatics and nerve supply7
Identification of the facial nerve
Facial nerve monitoring
Drawbacks of monitoring
Submandibular glands
Extent of the gland
Capsule
Relations of the superficial part12
Relations of the deep part4,12 (Figure 3.8)
Submandibular duct4
Blood supply, lymphatics and nerve supply12
Sublingual glands
Relations of the gland12 (Figure 3.9)
Ducts of the gland
Blood supply, lymphatics and nerve supply12
CHAPTER 4:
Historical perspective
CHAPTER 5:
Classifications
General classification of salivary gland diseases1
WHO histological classification of tumors of the salivary gland, 20022
CHAPTER 6:
Diagnosis and diagnostic aids
History
Physical examination
Parotid tumors
Submandibular gland tumors
Sublingual salivary gland
Minor salivary glands
Diagnostic aids
Diagnostic imaging
Plain radiographs
Ultrasonography
Doppler ultrasound and color-flow imaging
Sialography
Interpretation
Radionucleotide scanning
CT scan
MRI scan
Arteriography
Positron emission tomography
Histopathology
Fine needle aspiration cytopathology
Incisional biopsy
Frozen section
CHAPTER 7:
Non-neoplastic diseases
Acute bacterial sialadenitis
Epidemiology
Etiologic factors
Pathogenesis
Bacteriology
Clinical features
Investigations
Management
Complications
Chronic bacterial sialadenitis
Etiology
Clinical features
Microbiology
Diagnosis
Management
Complications
Obstructive disorders of the salivary glands
Sialolithiasis
Epidemiology
Etiologic factors
Pathophysiology
Clinical features
Diagnosis
Management
Viral infections of salivary glands
Mumps
Pathogenesis
Epidemiology
Virology
Clinical features1
Diagnosis
Treatment
Complications
Hiv Parotitis
Clinical features
Evaluation
Management
Non-infectious inflammatory diseases
Mikulicz's disease
Clinical features
Histopathology45
Management
Sjögren's syndrome
Etiology
Clinical features
Oral component
Ocular component
Autoimmune manifestation
Musculoskeletal manifestations
Respiratory tract involvement
Ear involvement
Gastrointestinal and hepatobiliary manifestations
Urinary tract involvement
Vascular involvement
Neuropsychiatric involvement
Other manifestations
Radiographic features
Histopathology
Differential diagnosis
Management
Cystic conditions
Mucoceles
Etiopathogenesis
Clinical features
Histopathology58
Differential diagnosis59
Management
Ranula
Clinical features
Histopathology58
Differential diagnosis59
Management
Salivary fistula
CHAPTER 8:
Etiology and pathogenesis of tumors
Pathophysiology of salivary gland tumors
CHAPTER 9:
Incidence of salivary gland neoplasms
CHAPTER 10:
Histogenesis of salivary gland neoplasms
Histogenetic concepts1
Mixed tumor
Adenoid cystic carcinoma
Squamous cell carcinoma and mucoepidermoid carcinoma
Oncocytic tumors
Acinous cell carcinoma
Adenocarcinoma
CHAPTER 11:
Surgical pathology of salivary gland neoplasms
Surgical pathology
Pleomorphic adenoma
Definition
Clinical features
Gross pathology12
Histopathology12
Immunoprofile13
Molecular genetics13
Management of pleomorphic adenoma of parotid gland
Management of pleomorphic adenoma of submandibular gland
Management of pleomorphic adenomas of the palate
Prognosis
Warthin's tumor
Clinical features
Gross pathology17
Histopathology17
Management of Warthin's tumor
Oncocytoma
Clinical features
Gross pathology24
Histopathology24
Management of oncocytoma
Monomorphic adenoma
Basal cell adenoma
Clinical features
Gross pathology28
Histopathological features28
Differential diagnosis
Management of basal cell adenomas
Canalicular adenoma
Clinical features
Gross pathology30
Histopathology30
Differential diagnosis
Management of canalicular adenomas
Ductal papilloma
Sialadenoma papilleferum
Clinical features
Gross pathology34
Histopathology34
Differential diagnosis
Treatment and prognosis
Inverted ductal papilloma
Clinical features34
Histopathology34
Treatment and prognosis
Intraductal papilloma
Clinical features34
Gross pathology34
Histopathology34
Treatment and prognosis
Malignant tumors of salivary glands
Mucoepidermoid carcinoma
Clinical features
Gross pathology41
Histopathology41
Grading of mucoepidermoid carcinoma
Management of mucoepidermoid carcinoma
Radiotherapy
Recurrence, metastasis and prognosis
Adenoid cystic carcinoma
Clinical features56
Gross pathology56
Histopathology56
Cribriform type
Tubular type
Solid type
Management of adenoid cystic carcinoma
Acinic cell adenocarcinoma
Clinical features
Gross pathology67
Histopathologic features67
Management of acinic cell adenocarcinoma
Malignant mixed tumor
Carcinoma ex-mixed tumor
Clinical features
Histopathology73
Management of carcinoma ex-mixed tumor
Carcinosarcoma
Clinical features
Gross pathology73
Histopathology73
Management of carcinosarcoma
Metastasizing mixed tumor
Clinical features73
Histopathology73
Management of metastasizing mixed tumor
Primary squamous cell carcinoma
Clinical features81
Gross pathology81
Histopathology81
Differential diagnosis81
Management and prognosis
Clear cell carcinoma
Clinical features84
Gross pathology84
Histopathology84
Differential diagnosis84
Management and prognosis
Epithelial–myoepithelial carcinoma
Clinical features85
Gross pathology85
Histopathology85
Differential diagnosis85
Management and prognosis
Undifferentiated carcinomas
Lymphoepithelial carcinoma
Clinical features90
Gross pathology90
Histopathology90
Differential diagnosis
Management and prognosis
Undifferentiated large cell carcinomas
Clinical features90
Gross pathology90
Histopathology90
Differential diagnosis
Prognosis
Small cell carcinoma
Clinical features90
Gross pathology
Histopathology90
Differential diagnosis
Management and prognosis
CHAPTER 12:
Surgical management of parotid neoplasms
Patient preparation
Skin incision and exposure of the gland3
Identification of the facial nerve
Tumor resection
Local excision of parotid gland8
Parotidectomy with preservation of the facial nerve
Complications
Functional superficial parotidectomy10
Advantages of functional superficial parotidectomy
Partial superficial parotidectomy
Intraoral deep lobe tumor excision13
Complications
Total parotidectomy with or without facial nerve preservation
Parotidectomy using smas plane for dissection6
Parotidomandibulectomy7
Temporoparotidectomy7
Parotidectomy in continuity with neck dissection
Reconstruction19
CHAPTER 13:
Surgical management of submandibular and sublingual neoplasms
Incision for access to submandibular gland
Incision for excision of sublingual gland
Extra capsular excision of the submandibular salivary gland3
Radical excision of neoplasms of the submandibular or sublingual salivary gland3
CHAPTER 14:
Surgical management of minor salivary gland neoplasms
Partial maxillectomy3
Incision
Surgical procedure
Total maxillectomy
Incision
Surgical procedure
Extended maxillectomy
Postoperative care
CHAPTER 15:
Complications of salivary gland surgery
Hematoma
Trismus
Salivary fistula
Facial nerve paresis or paralysis
Auriculotemporal syndrome of frey
Sensory abnormalities associated with greater auricular nerve sacrifice
CHAPTER 16:
Chemotherapy and radiotherapy
Chemotherapy in management of salivary gland neoplasms
INDEX
TOC
Index
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