Q.1. Define the followings:
- Pharmacy
- Forensic pharmacy
- Pharmacist
- Pharmaceutist
- Pharmaceutics
- Pharmacology
- Pharmacognosy
- Materia Medica
- Pharmacopeia
- Drug.
Ans.
- Pharmacy: It is the science and arts of preparing and compounding drugs for the purpose of patient administration. It covers the knowledge of identification, selection, preservation, combination, analysis and standardization of drug.
- Forensic Pharmacy: It covers the legal laws controlling trade and profession of pharmacy.
- Pharmacist: Authorized and qualified person to practice pharmacy.
- Pharmaceutist: Person skilled in pharmaceutics.
- Pharmaceutics: Science and art dealing with manufacture of drug.
- Pharmacology: Deals with sources, action, fate of drug in living organisms and their toxicities.
- Materia Medica: Obsolete terminology, now, deals with botanical and chemical properties of drugs and their therapeutic uses.
- Pharmacopeia: Published book by recognized authority of any country, containing list of accepted drugs, formulae for preparation, average dose, description and test for identification, purity and potency. Drugs included in pharmacopeia are called officials like IP, BP, rest of the drugs are ‘nonofficials’.
- Drugs: It is a substance or mixture of substances used for diagnosis, cure mitigation or prevention of a disease in men or animals.
Q.2. Define alkaloid? How you test it?
Ans. An alkaloid is complex nitrogenous substances, basic in nature due to presence of tertiary nitrogen, forms salts with acids. Insoluble in water but their salts are soluble, can be precipitated from their solution by heavy metals, alkalies, bromides, iodides, tannins and picric acid benzoates. Its name ends in “ine” viz. atropine, morphine, codeine, etc. Alkaloid may be tested by—
- Mayer's reagent (mercuric potassium iodide solution).
- Dragendorff's reagent (solution of potassium bismuth iodide).
- Wagner's reagent (solution of iodine with potassium).
- Reineckate reagent (solution of chromium ammonium thiocyanate).
- Marme's reagent (solution of potassium cadmium iodide).
- Sonnenschein's reagent (solution of phosphomolybdic acid).
Q.3. What are the qualitative test for glycoside?
Ans. It can be tested by Molisch reagent. In a test tube take 1ml of test solution, add 5 drops of 10% naphthol in alcohol. Pour 1ml of conc. H2SO4 by the side of the test tube. A red ring changing to purple (Molisch reaction).
Q. 4. How you will test for sterols?
Ans. It can be tested by—
- Libermann-Burchard reaction: Solution with chloroform, acetic anhydride and conc. H2SO4 gives blue color.
- Hess's reaction: Solution with chloroform and conc.H2SO4 gives red color.
- Hirschsohn's reaction: Solution with trichloroacetic acid and water gives red color.
Meaning of Some Latin Abbreviations and Words | ||
---|---|---|
Abbreviation | Latin | Meaning |
aa ad ad lib a.c. aq aq dest b.i.d. or b.d. c. co. div. dil. elix. emp. emul. et ft. gtt. h.s. Mist. o.d. p.c. pil. pulv. q.s. q.i.d. q.h. s.s. sig. S.O.S. Stat. t.i.d (td) M.ft. Mist tal | ana ad ad libitum ante cibos aqua aqua destillata bis in die cum compositus divide dilutus elixir emplastrum emulsum et fiat gutta, guttae hora somni Mistura omni die post cibos pilula pulvis quantum sufficit quarter in die quaque hora semis signa si opus sit statim ter in die misce fiat mistura tails | of each to, up to to be desired amount before meals water distilled water twice a day with compound divide dilute an elixir a plaster an emulsion and let it be made a drop, drops at bed time a mixture daily (once a day) after meals pill powder a sufficient quantity four times a day every hour half let it be marked if necessary immediately three times a day mixed to make a mixture of such |
METROLOGY
1 kilogram (kg) | = | 1000 grams (G, Gm, g) |
1 gram (G, Gm, g) | = | 1000 milligram (mg, mgm) |
1 milligram (mg) | = | 1000 microgram (mcg) |
1 ounce | = | 8 drachm = 480 grains |
1 drachm | = | 60 grains |
1 pound | = | 16 ounce |
1 ounce | = | 437.5 grains |
1 litre | = | 1000 milliliter |
1 gallon | = | 10 pounds |
1 pint | = | 20 fluid ounce |
1 fluid ounce | = | 8 fluid drachm |
1 fluid drachm | = | 60 minims |
1 grain | = | 64.8 mg |
1 ounce | = | 31.1035 gm |
2.2 pound | = | 1 kg |
1 minim | = | 0.062 ml (1 drop) |
1 fluid ounce | = | 30 ml (approx) |
1 seer | = | 940 Gm (2lb) |
1 teaspoonful | = | 4 ml (5 ml in USP) |
1 desserts spoonful | = | 8 ml |
1 tablespoonful | = | 15 ml |
1 % solution | = | 1:100 = 1 × 10–2 |
0.1% | = | 1:1000 = 1 × 10–3 |
1 in million | = | 1: 1000,000 = 1 × 10–6. |