Pranab Dey
MBBS MD MIAC FRCPath
Professor Department of Cytology and Gynecologic Pathology Postgraduate Institute of Medical Education and Research
Chandigarh, India
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Case-based Approach in Exfoliative Cytology
First Edition: 2017
9789386261892
FM5Dedicated to
Shree Satyananda Giri, Rini and Madhumanti
FM7PREFACE
In this book I have discussed many classical and interesting cases of exfoliative cytology. The book is written in the form of multiple choice questions (MCQs); and, therefore, it will help the students and the cytology practitioners to learn and self-evaluate. In each case I have discussed the diagnostic points and differential diagnosis along with salient immunocytochemistry. I hope that this case-based approach will be very effective in learning exfoliative cytology.
Pranab Dey
FM9ACKNOWLEDGMENTS
This book should be considered the second part of the previous book Case-based Approach in Fine Needle Aspiration Cytology. I again honestly acknowledge that the main concept of the book belongs to Shri Jitendar P Vij (Group Chairman) and Mr Ankit Vij (Group President) of M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India.
I wish to express my gratitude to Late Professor Subhash Kumari Gupta, and Professor Arvind Rajwanshi, Head of Cytology and Gynecologic Pathology, who taught me cytology.
I am grateful to Professor Uma Nahar Saikia and Dr Suvradeep Mitra for their assistance. They provided me the histopathology microphotographs. Dr Suvradeep Mitra deserves special thanks as he helped me throughout in the preparation of this manuscript.
My wife Rini and Madhumanti always gave me encouragement and support, and without their support it would not be possible to write this book.
I am grateful to God Almighty as the entire work is done by His blessings only.
FM13ABBREVIATIONS
AIDS
Acquired immunodeficiency disease
AGC
Atypical glandular cell
AGCUS
Atypical glandular cell of undetermined significance
ASC
Atypical squamous cell
ASCUS
Atypical squamous cell of undetermined significance
ASC-H
Atypical squamous cell high-grade SIL cannot be excluded
BCG
Bacillus Calmette-Guerin
BAL
Bronchoalveolar lavage
CSF
Cerebrospinal fluid
CIN
Cervical intraepithelial neoplasia
CD
Cluster differentiation
CK
Cytokeratin
CMV
Cytomegalovirus
DPAM
Disseminated peritoneal adenomucinosis
ERCP
Endoscopic retrograde cholangiopancreatectography
EUS TBNA
Endoscopic ultrasound guided transbronchial needle aspiration
EGFR
Epithelial growth factor receptor
EMA
Epithelial membrane antigen
FNAC
Fine needle aspiration cytology
FCM
Flow cytometry
GI
Gastrointestinal
GIST
Gastrointestinal stromal tumor
GLUT 1
Glucose transporter member 1
GM CSF
Granulocyte-macrophage colony stimulating factor
HSV
Herpes simplex virus
HSIL
High-grade squamous intraepithelial lesion
HPF
High power filed
HL
Hodgkin lymphoma
HIV
Human immunodeficiency virus
HPV
Human papilloma virus
HCG
Hyperchromatic crowded group
LC
Langerhans cell
LCC
Large cell carcinoma
LD body
Leishmania Donovani body
LCA
Leucocyte common antigen
FM14LBC
Liquid based cytology
LSIL
Low-grade squamous intraepithelial lesion
MGG
May Grunwald Giemsa
NSE
Neuron specific enolase
NHL
Non-Hodgkin lymphoma
N/C
Nucleocytoplasmic ratio
PAS
Periodic Acid-Schiff
PMCA
Peritoneal mucinous carcinomatosis
PCP
Pneumocystis pneumonia
PMP
Pseudomyxoma peritonei
PAP
Pulmonary alveolar proteinosis
PLCH
Pulmonary Langerhans cell histiocytosis
R-S cell
Reed Sternberg cell
SCC
Small cell carcinoma
SQC
Squamous cell carcinoma
TdT
Terminal deoxynucleotidase
TBS
The Bethesda system
TTF
Thyroid transcription factor
TV
Trichomonas vaginalis
USG
Ultrasonograph
UCC
Urothelial cell carcinoma
WHO
World Health Organization
ZN
Ziehl Neelsen stain