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Symptom Oriented Pain Management
Sanjay Bakshi, Sanjeeva Gupta, Dwarkadas K Baheti, Raghbir Singh P Gehdoo
SECTION 1: BASICS
CHAPTER 1:
Pain Management: A Historical Perspective
INTRODUCTION
HISTORICAL ASPECT
ROLE OF MEDICATION
CONCLUSION
CHAPTER 2:
Acute Pain
INTRODUCTION
ACUTE PAIN
Cause and Mechanism of Acute Pain
Rationale for Treatment of Acute Pain
CONCLUSION
CHAPTER 3:
Acute Turn to Chronic: Causes, Prevention, and Management
INTRODUCTION
CHRONIC POSTSURGICAL PAIN
RISK FACTORS FOR DEVELOPING CHRONIC POSTSURGICAL PAIN
Preoperative and Postoperative Pain
Surgical Types
GENETICS
Nerve Injury
PSYCHOSOCIAL
PATHOPHYSIOLOGY OF CHRONIC PAIN
Neuroplasticity
Peripheral and Central Sensitization
PREVENTION AND MANAGEMENT
Steroidal and Nonsteroidal Anti-inflammatory Drugs
Gabapentinoids
Ketamine
Regional Anesthesia
CONCLUSION
CHAPTER 4:
Chronic Pain
DEFINITION
PREVALENCE
ECONOMICS
CLASSIFICATION
CAUSES
ETIOLOGY
SOCIAL AND PSYCHOLOGICAL IMPACT
CONCLUSION
CHAPTER 5:
Interpretation of Blood Levels of Drugs Used in Chronic Pain Management
INTRODUCTION
General Principles Of Therapeutic Drug Monitoring
Why? (Table 1)
Indications for the TDM (TABLE 1)
Why Not?
How and when?
In the Laboratory11
Cost-effectiveness of TDM
TDM OF CHRONIC PAIN MEDICATIONS
Antiepileptic Agents
Gabapentin14–19
Lamotrigine
Carbamazepine
Phenytoin
Tiagabine and Vigabatrin
Tricyclic Antidepressants
Selective Serotonin Inhibitor and Serotonin Noradrenaline Reuptake Inhibitors30
Opioids
TDM for Opioids
Nonsteroidal Anti-inflammatory Drugs
Salicylates37
Ibuprofen and Naproxen
Paracetamol37
Issues in Special Populations
CONCLUSION
SECTION 2: CLINICAL EXAMINATION AND EVALUATION
CHAPTER 6:
Clinical Examination and Evaluation of Cervical Spine
INTRODUCTION
CAUSES
Anatomical Considerations
HISTORY
EXAMINATION
Inspection
Range of Movements
Palpation of Spine
Examination of Peripheral Joints
NEUROLOGICAL EXAMINATION
Examination of Myotomes
Sensory and Motor Examination
Conclusion
CHAPTER 7:
Clinical Examination and Evaluation of Lumbar Spine
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
TREATMENT PROTOCOL
CONCLUSION
SECTION 3: UNDERSTANDING IMAGING MODALITIES FOR PAIN PATIENT
CHAPTER 8:
Interpretation of X-ray Spine
AIMS
ROLE OF X-RAY IN PAIN MEDICINE
RADIOLOGICAL ANATOMY OF SPINE
Cervical Spine
Thoracic Spine
Lumbar Spine
Sacroiliac Joints
HOW TO INTERPRET A SPINE X-RAY?
A: Alignment
B: Bone Morphology
C: Cartilage
D: Disk Height
E: End-plate of the Vertebral Body
F: Facet Joints
S: Soft Tissue and Structures Around
CONCLUSION
CHAPTER 9:
Interpretation of Computer Tomography Scans for Interventional Pain Treatment Procedures
INTRODUCTION
BASIC PROCEDURES
Arnold Nerve Infiltration
Cervical Root Injections
Thoracic Costovertebral and Facet Injection
Lumbar Epidural Injections
Lumbar Periradicular Injection
Lumbar Facet Joint Injections
Lumbar Spondylolysis Test Infiltration
Lumbar Synovial Cyst Infiltration
Sacroiliac Joint Injection
ADVANCED PROCEDURES
Trigeminal Ganglia Neurolysis or Radiofrequency
Sphenopalatine Ganglia Neurolysis or Radiofrequency
Stellate Ganglion Neurolysis or Radiofrequency
Splanchnic Nerve Neurolysis
Coeliac Ganglia Neurolysis
Anterior Approach
Lumbar Plexus Neurolysis
Nucleoplasty—Disc Decompression with Laser/RF
Vertebroplasty
Transpedicular Approach
Posterolateral Approach
CONCLUSION
CHAPTER 10:
Magnetic Resonance Imaging in Pain Management
INTRODUCTION
MRI IN BACK PAIN
The Degenerative Spinal Disease
Lumbar Spine
MR Imaging of Normal Disk and Disk Pathologies
Degenerative Pathologies other than Disk
The Facet Joints and Pathologies
THE CERVICAL SPINE
VERTEBRAL BODY COLLAPSE
IMAGING IN INFLAMMATORY SPONDYLOARTHROPATHY
THE SPINAL TUMORS
THE BONE MARROW PATHOLOGIES
SPINAL INFECTIONS
MRI IN POSTOPERATIVE SPINAL PAIN
MRI IN CHRONIC ABDOMINAL PAIN
CONCLUSION
CHAPTER 11:
Role of Electrodiagnosis in the Management of Neck and Back Pain
INTRODUCTION
HOW DOES ELECTRONEUROMYOGRAPHY HELP?
WHY ELECTRONEUROMYOGRAPHY IN BACK AND NECK PAIN?
PROTOCOL
EQUIPMENT
ELECTRONEUROMYOGRAPHY TESTS
Nerve Conduction Studies
Sensory Nerve Action Potential SAP/SNAP
Motor Nerve Conduction
Needle Electromyography Examination or Electromyography
Late Responses
F-Waves
H Reflex Study
Somatosensory Evoked Potential Study
Neural Deficits Associated with Back or Neck Pain
Electroneuromyography in Root Lesions Correlated with Pathophysiology
CONCLUSION
Limitations of Electroneuromyography
Electroneuromyography in Postoperative Care
Electroneuromyography Versus Imaging
What Should Your Patient Expect?
Nerve Conduction Studies
Electromyography
How can the Referring Doctor Help?
What if the Working Diagnosis is Inaccurate?
What to Look for in an ENMG Report?
REVIEW OF RECENT LITERATURE
CHAPTER 12:
Bone Mineral Density: Interpretation, Treatment, and Prevention
INTRODUCTION
PATHOPHYSIOLOGY
RISK FACTORS
Fixed Risks
Modifiable Risks
DIAGNOSIS
INDICATIONS
CONTRAINDICATIONS
TREATMENT
PREVENTION
CONCLUSION
SECTION 4: CERVICAL/NECK PAIN
CHAPTER 13:
Headache: Causes and Treatment Modalities
INTRODUCTION
CAUSES
CLINICAL EXAMINATION
History
Temporal Profile
Age
Location and Type
Tension-type Headache
Accompaniments
Provoking and Relieving Factors
Past Medical History
Physical Examination
DIAGNOSTIC CRITERIA
INVESTIGATIONS
Laboratory Testing
Cerebrospinal Fluid Examination
Neuroimaging
DIFFERENTIAL DIAGNOSIS
Primary Headaches
Migraine
Treatment
Tension-type Headache
Cluster Headache
Other Trigeminoautonomic Cephalgias and Short-lasting Headaches
Secondary Headaches
Raised Intracranial Pressure
Intracranial Hemorrhage
Meningitis
Idiopathic Intracranial Hypertension
Sinusitis-associated Headache
Medication Overuse Headache
EMERGENCY TREATMENT
HEADACHE CLINIC
CONCLUSION
CHAPTER 14:
Trigeminal Neuralgia: Causes and Treatment
INTRODUCTION
CLASSIFICATION OF TRIGEMINAL NEURALGIA
DIAGNOSIS
ANATOMICAL PERSPECTIVE
MANAGEMENT OPTIONS
Natural History
Pharmacological Management
Neurosurgical Management Option
PERCUTANEOUS INTERVENTIONS
Indications for Radiofrequency/Balloon Microcompression/Glycerol Injection for Trigeminal Neuralgia
SALIENT FEATURES RELATED TO EACH INTERVENTION AS RELEVANT IN PRACTICE
Radiofrequency Thermocoagulation of the Gasserian Ganglion
Balloon Microcompression of the Gasserian Ganglion
Trigeminal Glycerol Injection
Contraindications to Rodiofrequency or Balloon Microcompression or Glycerol Injection
Radiofrequency Thermocoagulation of Gasserian Ganglion
Preparation
Technique
Important Technical Considerations
Balloon Microcompression of the Gasserian Ganglion
Important Technical Considerations
Trigeminal Glycerol Injection
Technique
Important Technical Considerations
Postprocedure Care Following Radiofrequency/Balloon/Glycerol Injection
Side Effects and Complications of Radiofrequency/Balloon Compression/Glycerol Injection
PATIENT REPORTED OUTCOMES FROM AN AUDIT FROM AUTHOR'S UNIT
BILATERAL TRIGEMINAL NEURALGIA
ALTERNATIVE NEUROABLATIVE OPTIONS
CONCLUSION
CHAPTER 15:
Cervical Radiculopathy Pain and Its Management
INTRODUCTION
CAUSES
Factors that Contribute to Cervical Radiculo Pathy
SYMPTOMS AND SIGNS
CLINICAL EXAMINATION
Inspection
Palpation
Foraminal Compression Test (Spurling Test)
Shoulder Abduction Test
Neck Distraction Test
DIAGNOSTIC CRITERIA
Investigations Suggested
Blood Tests
Magnetic Resonance Imaging
Computerized Tomography
Electromyography
Selective Nerve Root Block
Differential Diagnosis
Treatment
Medication
Physical Therapy
Cervical Epidural Steroid Injection
Nucleoplasty
Cervical Traction
Surgery
FOLLOW-UP ADVICE
CONCLUSION
CHAPTER 16:
Cervical Facet Joint Pain and Its Management
INTRODUCTION
CAUSES
SYMPTOMS AND SIGNS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
PROBLEM DEFINITION
Medications and Interventions
Interventional Treatment Procedures
Follow up After Interventional Pain Treatment
CONCLUSION
CHAPTER 17:
Cervical Diskogenic Pain and Its Management
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
DIAGNOSIS AND TREATMENT ALGORITHM
CERVICAL DISKOGRAPHY
TREATMENT
CONCLUSION
SECTION 5: LOW BACK PAIN
CHAPTER 18:
Focal Back Pain and Its Management
INTRODUCTION
CAUSES
MECHANICAL CAUSES OF FOCAL LOW BACK PAIN
Symptoms, Signs and Clinical Examination
Diagnostic Criteria
Investigations
Differential Diagnosis
Treatment
Conservative Management and Pharmacotherapy
NONMECHANICAL CAUSES OF FOCAL LOW BACK PAIN
DESCRIPTION OF SOME COMMON CAUSES OF NONMECHANICAL FOCAL LOW BACK PAIN ENCOUNTERED IN THE PAIN CLINIC
Osteoporosis and Focal Back Pain
Malignancy and Focal Back Pain
Infection of Spine and Focal Back Pain
Ankylosing Spondylitis and Focal Back Pain
CONCLUSION
CHAPTER 19:
Lumbar Facet Joint Pain Syndrome
INTRODUCTION
PREVALENCE AND EPIDEMIOLOGY
ANATOMY
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
TREATMENT
CONCLUSION
CHAPTER 20:
Lumbar Spinal Stenosis
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION AND FINDINGS
DIAGNOSTIC CRITERIA AND IMAGING
TREATMENT OPTIONS
CONCLUSION
CHAPTER 21:
Lumbar Diskogenic Back Pain
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS SUGGESTED
DIFFERENTIAL DIAGNOSIS
TREATMENT PROTOCOL
CONCLUSION
CHAPTER 22:
Sacroiliac Joint Pain Syndrome and Its Management
INTRODUCTION
CAUSES OF SACROILIAC JOINT PAIN SYNDROME
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS
Laboratory Tests
Imaging Studies
Diagnostic Blocks
DIFFERENTIAL DIAGNOSIS
TREATMENT PROTOCOL
FOLLOW-UP ADVICE
CONCLUSION
CHAPTER 23:
Coccygodynia and Its Pain Management
INTRODUCTION
CLINICAL ANATOMY
ETIOLOGY
SIGNS AND SYMPTOMS
PHYSICAL EXAMINATION
DIAGNOSTIC AND IMAGING WORK-UP
Imaging
TREATMENT STRATEGY
Nonsurgical Management
Injections Using Steroid or Local Anesthetic6
Coccygeal Nerve Block
Ganglion Impar Block
Pulsed Radiofrequency
Dextrose Prolotherapy
Spinal Cord Stimulation
Coccygeoplasty
Surgical Management
CONCLUSION
CHAPTER 24:
Piriformis and Iliopsoas Pain Syndromes and Its Pain Management
PIRIFORMIS SYNDROME
Introduction
Anatomy
Etiology
Etiopathology
Differential Diagnosis
Diagnostic Criteria
Treatment Plan
Fluoroscopy-guided Piriformis Injection Technique
Ultrasound Guidance for Piriformis Block (Fig. 3)
PSOAS OR ILIOPSOAS SYNDROME
Introduction
Symptoms
Diagnosis
Treatment
Iliopsoas Injection Technique
Iliopsoas Bursa Injection Procedure
Iliopsoas Tendon Injection Procedure
CONCLUSION
SECTION 6: UROGENITAL AND PELVIC PAIN
CHAPTER 25:
Nonmalignant Urogenital Pain Management
INTRODUCTION
NEUROANATOMY OF PELVIS AND PERINEUM
CHRONIC PROSTATITIS (CHRONIC PROSTATE PAIN)
Symptoms
PROSTADYNIA
Treatment
ORCHIALGIA/TESTICULAR PAIN
BLADDER PAIN SYNDROME (INTERSTITIAL CYSTITIS)
Treatment
VULVAR PAIN SYNDROME (VULVODYNIA)
URETHRAL PAIN SYNDROME
ANORECTAL PAIN SYNDROMES
Levator Ani Syndrome
Proctalgia Fugax
PUDENDAL NEURALGIA
COCCYGODYNIA
Treatment
GENERALIZED TREATMENT OF UROGENITAL PAIN
Medications
Paracetamol
NSAIDs
Tricyclic Antidepressants TCAs
Anticonvulsants
N-methyl-D-aspartate (NMDA) Antagonists
Ketamine
Opioids
Interventional Procedures
CONCLUSION
CHAPTER 26:
Chronic Nonmalignant Pelvic Pain
INTRODUCTION
DEFINITIONS
EPIDEMIOLOGY
ETIOLOGY
ASSESSMENT
History
Examination
Investigations
MANAGEMENT/TREATMENT OPTIONS
Multidisciplinary Team Approach
Specific Treatment
Pharmacotherapy
Stimulation/Modulation
Interventional Procedures
CONCLUSION
SECTION 7: CANCER PAIN
CHAPTER 27:
Head and Neck Cancer Pain Management
INTRODUCTION
PREVALENCE OF PAIN IN HEAD AND NECK CANCER
ETIOLOGY OF HEAD AND NECK CANCER-RELATED PAIN
Pain Due to Head and Neck Cancer
Pain Due to Chemotherapy and Radiotherapy
Pain Due to Surgery
ASSESSMENT OF HEAD AND NECK CANCER-RELATED PAIN
MANAGEMENT OF HEAD AND NECK CANCER-RELATED PAIN
Role of Surgery
Chemotherapy and Radiotherapy-induced Pain
Oral Mucositis
Pharmacological Management of Pain in HNC
Systemic Medications
Breakthrough Pain (BTP)
Adjuvant Analgesics
Interventional Pain Management
Cognitive and Other Pain Management Options
Noninvasive MR-guided Neuroablative Technique
CONCLUSION
CHAPTER 28:
Breast Cancer: Pain and Its Management
INTRODUCTION
SYMPTOMATOLOGY
Pain Due to Tumor
TREATMENT-RELATED PAIN
Surgery
Radiation Therapy
Chemotherapy
Pain Management Strategies
Management of Breakthrough Pain
Noble Pharmacological Therapies
CB2 Agonist
Tetrodotoxin
Botulinum Toxin
Caffeine
Soy Isoflavones
CONCLUSION
CHAPTER 29:
Carcinoma Lung: Pain and Its Management
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
TREATMENT
FOLLOW-UP ADVICE
CONCLUSION
CHAPTER 30:
Upper Abdominal Malignancy: Pain and Its Management
INTRODUCTION
CAUSES OF CHRONIC UPPER ABDOMINAL PAIN
SYMPTOMS AND SIGNS
DIAGNOSTIC CRITERIA
General Examination
Examination of Abdomen
Inspection
Palpation
Auscultation
INVESTIGATIONS
Blood Tests
Other Tests
TREATMENT PROTOCOL
Pharmacological
Analgesics
Antispasmodics
Laxatives
Interventional Treatment Procedures
Basic Procedures
Advanced
Nutritional Supplements
COMPLICATIONS
CONCLUSION
CHAPTER 31:
Malignant Pelvic Pain and Its Management
INTRODUCTION
PATHOPHYSIOLOGY OF PELVIC PAIN
ANATOMICAL CONSIDERATION
Endometriosis Painful Conditions in Women
Adenomyosis
Uterine Leiomyoma
Endometrium Cancer
Cervix Cancer
Condyloma
Bony Tumors of Pelvis
Chondrosarcoma
Ewing's Sarcoma
Carcinoma of Urinary Bladder
Prostate Cancer
Prostatic-specific Antigen or PSA Test
TESTICULAR TUMORS
COCCYDYNIA
Pain Description of Pelvic Pain Patients
MANAGEMENT OF PELVIC PAIN
Neural Blockade for Relief of Pelvic Pain
Sympathetic Nerve Block
Lumbar Sympathetic Block
Superior Hypogastric Plexus Block
Ganglion of Impar
Sacral Nerve Root Block
Subarachnoid and Epidural Neurolytic Block
Saddle Block
Subarachnoid vs Epidural Neurolysis
CONCLUSION
ACKNOWLEDGMENT
CHAPTER 32:
Metastatic Bone Pain Management
INTRODUCTION
MECHANISMS OF BONE METASTASIS
CLINICAL FEATURES
Pain
Bone Fracture
Spinal Cord Compression
Other Symptoms
DIAGNOSIS
Laboratory Tests
Radiographic Examination
Plain X-ray
Computerized Tomography Scan
Magnetic Resonance Imaging
Bone Marrow Aspiration and Biopsy
Bone Scan
Positron Emission Tomography Scans
TREATMENT OPTIONS
Pain Management Therapy
Chemotherapy
Hormonal Therapy
Radiation Therapy
Systemic Radioisotope Pharmaceutical Therapy
Indications
Contraindications
Precautions
Medical Therapy
Bone-targeting Agents (Bisphosphonates)
Calcitonin
Denosumab
Surgical Therapy
Other Interventions
Nonpharmacologic Management
Cutaneous Therapy
Transcutaneous Electrical Nerve Stimulation
Massage Therapy
Exercise
Psychotherapeutic Management
CONCLUSION
SECTION 8: NEUROPATHIC PAIN
CHAPTER 33:
Neuropathic Pain: Approach, Pathophysiology, and Management
INTRODUCTION
DEFINITION
ETIOLOGY
PATHOPHYSIOLOGY
Peripheral Mechanisms
Sensitization
Central Sensitization
Central Modulation of Pain
CLINICAL APPROACH
History
EXAMINATION
INVESTIGATIONS
MANAGEMENT
PHARMACOTHERAPY
Principles of Therapy
Trigeminal Neuralgia
INTERVENTIONAL PAIN MANAGEMENT
CONCLUSION
SECTION 9: ISCHEMIC PAIN
CHAPTER 34:
Peripheral Vascular Disease: Causes and Pain Management
INTRODUCTION
ETIOPATHOPHYSIOLOGY
Etiology
Pathophysiology
CLASSIFICATION
Fontaine Stages
Rutherford Categories
Asymptomatic/Claudication/Critical Limb Ischemia/Acute Limb Ischemia
HISTORY
Symptoms
Other Symptoms and Signs
CLINICAL EXAMINATION
LABORATORY STUDIES
IMAGING STUDIES
OTHER TESTS
TREATMENT
Immediate Management
In Hospital Management
ACUTE LIMB ISCHEMIA
Nonviable Limb
Viable Limb
Anticoagulants
Claudication (Not lifestyle-limiting)
Claudication (Lifestyle-limiting)
CHRONIC SEVERE LIMB ISCHEMIA (CRITICAL LIMB ISCHEMIA)
Revascularization Referral
Procedures (Endovascular or Surgical Revascularization)
CONTINUED INTERVENTIONAL MANAGEMENT
Surgical Management
Amputation
Pain Relief
Role of Interventional Pain Procedures
CONCLUSION
SECTION 10: MYOFASCIAL PAIN
CHAPTER 35:
Management of Myofascial Pain
INTRODUCTION
RELEVANT ANATOMY
CLINICAL FEATURES
DIAGNOSING MYOFASCIAL PAIN
History
Examination
Investigations
DIFFERENTIAL DIAGNOSIS
MANAGEMENT
Available Therapeutic Options6 (Evidence and Recommendations)
Pharmacologic Treatment of Myofascial Pain
Nonpharmacologic Treatment Options
CONCLUSION
ADDENDUM
CHAPTER 36:
Fibromyalgia: Causes and Pain Management
INTRODUCTION
HISTORY
EPIDEMIOLOGY
PATHOLOGY
CLINICAL FEATURES
SYMPTOMS
SIGNS
LIMITATIONS
MANAGEMENT
INVESTIGATIONS
TREATMENT
Nonpharmacological Treatment
Counseling
Exercises
Relaxation Techniques
Mind and Body Therapy
Aquatic Exercise Training for Fibromyalgia
Cognitive Behavioral Therapy
Tips to Get Sound Sleep
Pharmacological Treatment
Medications to Diminish Pain
Other Medications Used
Newer Strategies
CONCLUSION
SECTION 11: SCAR PAIN
CHAPTER 37:
Post-herniorrhaphy Pain and Its Management
INTRODUCTION
ANATOMY OF INGUINAL CANAL
NEUROANATOMY OF ILIOINGUI-NAL NERVE
NEUROANATOMY OF ILIOHYPO-GASTRIC NERVE (FIG. 2)
GENITOFEMORAL NERVE
TREATMENT MODALITIES FOR CHRONIC POSTSURGICAL INGUINAL PAIN
Preventive Approach
Therapeutic Approach
CONCLUSION
CHAPTER 38:
Post-coronary Artery Bypass Grafting Scar Pain and Its Management
INTRODUCTION
PREVALENCE OF POST-THORACOTOMY PAIN
CAUSES 5–7
CLINICAL EXAMINATION
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
TREATMENT PROTOCOL
CONCLUSION
SECTION 12: CHALLENGING PAIN
CHAPTER 39:
Complex Regional Pain Syndrome: Where We Stand?
INTRODUCTION
CAUSES
GENETICS IN COMPLEX REGIONAL PAIN SYNDROME
Role of Glia
SYMPTOMS AND SIGNS
DIAGNOSTIC CRITERIA
INVESTIGATIONS SUGGESTED
Thermography
Radiography
Bone Scintigraphy
Electrodiagnostic Testing
Neuropsychological Testing
CRPS in Children
TREATMENT PROTOCOL
Medications
Low Dose Naltrexone
Physical Therapy
Psychotherapy
Sympathetic Nerve Block
MC5-A Calamare Device
HYPERBARIC OXYGEN THERAPY
Amputation
Spinal Cord Stimulator
Intrathecal Pumps
Ketamine
CHAPTER 40:
Phantom Limb Pain: Causes and Pain Management
INTRODUCTION
SIGNS and SYMPTOMS
CAUSES
CLINICAL EXAMINATION
DIAGNOSTIC CRITERIA
INVESTIGATIONS
Differential Diagnosis
TREATMENT PROTOCOL
Mirror Box Manipulation
Transcutaneous Electrical Nerve Stimulations
Stump Neuromas
Sympathetic Nerve Blocks
Surgical Treatment
Invasive Procedures
CONCLUSION
CHAPTER 41:
Postherpetic Neuralgia: Causes and Pain Management
INTRODUCTION
SIGNS AND SYMPTOMS
CLINICAL EXAMINATION
TREATMENT OPTIONS
Antiviral Treatments
Chemical Neuromodulatory Therapies
Interventional Techniques
Other Pharmacologic Options
Vaccinations for Shingles
Contraindications for the Vaccine
Side Effects from the Vaccine
CONCLUSION
CHAPTER 42:
Post-laminectomy Pain and Its Management
INTRODUCTION
ETIOLOGY
PATHOPHYSIOLOGY
CLINICAL EVALUATION
HISTORY
EXAMINATION
DIFFERENTIAL DIAGNOSIS
INVESTIGATIONS
Plain X-rays
MRI Scan
CT Myelography
Bone Scan
Neurophysiology
Laboratory Studies
Color Doppler
MANAGEMENT
Repeat Surgery
Pharmacotherapy
Simple Analgesics and NSAIDs
Muscle Relaxants
Antidepressant Drugs (TCAs, SNRI, SSRI)
Antiepileptic Drugs
Antiarrhythmic Drugs
Steroids
Tramadol and Codeine
Strong Opioids
Pain Interventions
Transforaminal Epidural Injection
Facet Blocks
Radiofrequency Ablation
Sacroiliac Joint Injection1
Caudal Epidural Injection
Epidural Neuroplasty
Epiduroscopy
Other Interventions
Neuromodulation2
Physiotherapy and Rehabilitation
Psychological Counseling and Cognitive Behavioral Therapy
CONCLUSION
CHAPTER 43:
Restless Leg Syndrome: Causes and Pain Management
INTRODUCTION
CAUSES
DIAGNOSTIC CRITERIA FOR RESTLESS LEG SYNDROME
PREVENTIVE TIPS FOR RESTLESS LEG SYNDROME
Symptoms and Signs
CLINICAL EXAMINATION
Physical Examination
Neurological Examination
INVESTIGATIONS
Blood Investigation
Sleep Studies
DIFFERENTIAL DIAGNOSIS
TREATMENT PROTOCOL
Medications
Nonpharmacologic Therapy
Interventional
Preventive/Avoid
Risk Involved to Watch for During the Treatment
CONCLUSION
CHAPTER 44:
Calciphylaxis and Its Pain Management
INTRODUCTION
BACKGROUND
EPIDEMIOLOGY
PATHOPHYSIOLOGY
DIAGNOSIS
CLINICAL FEATURES
History
Physical Findings
CAUSES/ASSOCIATION (TABLE 1)
Differential Diagnosis
Laboratory Studies
Imaging Studies
TREATMENT
Sodium Thiosulfate
Bisphosphonates
Hyperbaric Oxygen Therapy
Steroids
Sterile Maggot Therapy
PAIN MANAGEMENT
CONCLUSION
CHAPTER 45:
Regenerative Medicine for Spine and Orthopedic Conditions
INTRODUCTION
HISTORICAL BACKGROUND
BIOLOGIC AGENT SOURCES
BIOCELLULAR CHEMISTRY
CLINICAL CONSIDERATIONS
INDICATIONS AND APPLICATIONS
PROCEDURAL PROTOCOLS
CONTRAINDICATIONS
LEGISLATIVE AND ETHICAL UPDATE
CONCLUSION
SECTION 13: PHYSIOTHERAPY
CHAPTER 46:
Role of Physiotherapy in Treatment of Patients with Spinal Pain During the Acute/Inflammatory Phase
INTRODUCTION
CAUSES OF SPINAL PAIN
SYMPTOMS
CLINICAL EXAMINATION
TREATMENT
Neutral Spine
First Aide Positions
CONCLUSION
CHAPTER 47:
Role of Physiotherapy in Treatment of Spinal Pain During Subacute/Reparative Phase
INTRODUCTION
GOALS OF PHYSICAL THERAPY TREATMENT
SIGNS AND SYMPTOMS
Signs
Symptoms
CLINICAL EXAMINATION
INVESTIGATIONS SUGGESTED
PHYSICAL THERAPY TREATMENT
Body Mechanics and Postural Education
Muscle Re-education
Manual Therapy
Therapeutic Exercises
Cardiovascular Training
CONCLUSION
CHAPTER 48:
Physiotherapy in Management of Chronic Pain
INTRODUCTION
CAUSES
EVALUATION/ASSESSMENT
GOALS OF TREATMENT
INTERVENTIONS FOR PAIN MANAGEMENT
ELECTROTHERAPEUTIC MODALITIES
Short–wave Diathermy
Ultrasound
Cryotherapy
Neuromuscular Electrical Stimulation
Iontophoresis
Transcutaneous Electrical Nerve Stimulation
Interferential Current
Light Amplification by Simulation Emission of Radiation
Electromyography Biofeedback
MANUAL THERAPY TECHNIQUES
CONCLUSION
SECTION 14: PSYCHIATRY
CHAPTER 49:
Role of Psychiatric Medications in Chronic Pain Management
INTRODUCTION
CHRONIC PAIN
WHY PSYCHIATRIC MEDICATIONS IN CHRONIC PAIN?
PSYCHIATRIC MEDICATIONS IN CHRONIC PAIN
Antidepressants
Serotonin-norepinephrine Reuptake Inhibitors (SNRIs)
Tricyclic and Tetracyclic Antidepressants (TCAs)
Selective Serotonin ReuptakeInhibitors
PSYCHOTHERAPY
CONCLUSION
CHAPTER 50:
Pain Psychology and Its Treatment Options
INTRODUCTION
CAUSES
SIGNS AND SYMPTOMS
PAIN AND DEPRESSION
PAIN AND ANXIETY
DIAGNOSTIC CRITERIA
INVESTIGATIONS
DIFFERENTIAL DIAGNOSIS
TREATMENT
Important Tips for Medical Practitioners
CONCLUSION
SECTION 15: ALLIED THERAPY
CHAPTER 51:
Role of Radiation in Cancer Pain
INTRODUCTION
TYPES OF RADIATION
MECHANISM OF PAIN RELIEF BY RADIATION
METASTATIC BONE PAIN MANAGEMENT
Isotope Therapy for Metastatic Bone Pain
Mechanism of Action
Targeted Isotope Therapy
177-Lutetium-PSMA Therapy for Bone Metastases from Prostate Cancer
223-Radium Alpha Radiation Therapy for Metastatic Prostate Cancer
177-Lutetium-DOTATATE Therapy for Neuroendocrine Tumor Patients
Yttrium-90 (Y-90) Radioembolization Treatment for Liver Cancer
Radioiodine (131-I) Treatment in Thyroid Cancer
131-I-MIBG Therapy for Metastatic Neuroblastoma
ROLE OF EXTERNAL RADIATION THERAPY IN CHRONIC PAIN MANAGEMENT
External RT in Brain Tumors
Pain due to Infiltration or Plexus or Peripheral Nerve
Brachytherapy
CONCLUSION
CHAPTER 52:
Role of Chemotherapy in Cancer Pain Management
INTRODUCTION
TYPES OF CANCER PAIN
CAUSES OF CANCER PAIN
TREATMENT MODALITIES FOR CANCER PAIN
Cytotoxic Chemotherapy
Effect of Chemotherapy on Cancer Pain
Performance Status
Comorbidities
Biological and Targeted Therapies in Management of Cancer Pain
Hormone Therapy in the Management of Cancer Pain
Bone-directed Therapies in the Management of Cancer Pain
HOW TO INTEGRATE CANCER- DIRECTED SYSTEMIC THERAPIES IN MANAGEMENT OF CANCER PAIN?
WHEN TO STOP CANCER-DIRECTED SYSTEMIC THERAPIES
CONCLUSION
CHAPTER 53:
Oncosurgery and Cancer Associated Pain
INTRODUCTION
DEFINITION AND UNDERSTANDING CONCEPTS IN SURGICAL PALLIATION FOR CANCER
INDICATIONS FOR SURGICAL PALLIATION
PATIENT SELECTION FOR PALLIATIVE SURGERY
THE EVIDENCE AND THE OUTCOMES
CONCLUSION
ACKNOWLEDGMENTS
CHAPTER 54:
Management of Ophthalmic Pain
INTRODUCTION
CHEMICAL INJURIES
Acute Glaucoma
UVEITIS
Commonly Encountered Causes of Chronic Pain Include
Ischemic Etiologies
Common Causes of NVG Include
General Principles Include
END-STAGE TREATMENT
Infective and Neuropathic Causes
Pathophysiology
Clinical Presentation
Ocular Complications Include
Treatment of HZO
Antiviral Treatment
Corticosteroid Therapy
Treatment of Ophthalmic Complications
Treatment of Postherpetic Neuralgia
FLUOROSCOPIC TECHNIQUE
CT-GUIDED TECHNIQUE
Inflammatory Causes: These Include
Specific Orbital Tumors: Common Types Include
CONCLUSION
INDEX
TOC
Index
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