A
Acid-base derangements 297
Acidosis 177
Acquired immune deficiency syndrome 290
Acquired platelet dysfunction, causes of 167
Addison's disease 409
Adenitis 430
Adenoma 230
Adenosine monophosphate, cyclic 16
Adhesion molecule deficiency 185
Aicardi-Goutières syndrome 409
Albinism-neutropenia syndrome 191
Alkaline phosphate 185
Allergic reactions 296
Alpha-1 acid glycoprotein 268
Alpha-1 anti-trypsin deficiency 128
Alpha-gamma storage pool deficiency 175
Alport syndrome 163
Altman classification 256f
American Academy of Pediatrics 128
American Joint Committee on Cancer 263
Amniocentesis 445
Anaplastic large-cell lymphoma 390
Anaplastic lymphoma kinase 239
aplastic 104
chronic 278
dimorphic 67
megaloblastic 67
nonimmune hemolytic 87
pernicious 409
prevention of 68
Angioedema, hereditary 423
Angiotensin-converting enzyme inhibitors 288
Aniridia syndrome 245
Anticoagulation systems 142f
Antiglobin test 78
Anti-neutrophil antibody-mediated disorders 211
Antithrombotic therapy 149
Aorta-gonad-mesonephros region 13
APGAR score 65
Apoptosis, X-linked inhibitor of 398
Apoptotic pathways 405f
Arachidonic acid 169
Artemis deficiency 358
Arterial blood gases 113
Artery, umbilical 30
Arthralgia 434
Atresia, esophageal 255
Autoimmune
Autoinflammatory
B
Bacterial sepsis, severe 226
Bacteroides 89
Barium sulphate adsorbed plasma 121
Bart's disease 45
Beckwith-Wiedemann syndrome 245
Behçet disease 361
Bicytopenia 209
Bile duct atresia 129
Biliary hypoplasia 128
Bland spindle cells 245
Blindness, congenital 45
Blood
components, gamma irradiation of 288
counts, normal 4
group incompatibilities 226
irradiator, dosimetry of 290
products 363
sugar 113
transfusion 72
therapy 277
warming of 287
Blueberry muffin appearance 226f
Bronchial-associated lymphoid tissue 331
Bronchiectasis, management of 438
Bruch's membrane 264
Buckley disease 438
Byler disease 129
C
Campylobacter jejuni 369
Candida albicans 338
Candida parapsilosis 338
Carboxyhemoglobin 88
Cell lines, maturation of 50f
Cellular blood components, leukocyte depletion of 288
Cephalhematoma 119
Cerebellum 65
Chemotaxis, disorders of 199
Chemotherapy 259
Chickenpox 363
Cholestasis syndrome 161
Chorioamnionitis 295
Circle of Willis 26
Citrate phosphate dextrose 295
Classic autoinflammatory syndromes 429
Clostridium perfringens 89
Clostridium welchii 89
Coagulation tests 137
Cold autoinflammatory, familial 433
Collagen adenosine diphosphate 168
Colostrum 332
Complex regional multifocal osteomyelitis 433
Congenital high airway obstruction syndrome 258
Connective tissue disorders 175
Corpus striatum 65
Corticosteroid therapy 185
Corticotropin-releasing hormone 64
C-reactive protein 210
Creutzfeldt-Jakob disease 296
Crigler-Najjar syndrome 45
Cryptosporidium 361
Cytokine 14
D
Dandy-Walker malformation 255
Dense tubular system 20
Denys-Drash syndrome 245
Deoxyadenosine triphosphate 358
Dermatofibrosarcoma 252
Dianzani autoimmune lymphoproliferative disease 406
Diaphragmatic hernia, congenital 258
Diarrhea 434
Diencephalic syndrome 221f
Diethylaminoethyl column chromatography 82
Diffuse infantile hepatic hemangioma 231
Dithiothreitol method 82
Double volume exchange transfusion 139
Duodenal atresia 103
Dysproteinemia 167
E
Ectodermal dystrophy 409
Eczema 378
Edward syndrome 161
Elevated liver transaminases 396
Elliptocytosis, hereditary 93
Ellis-Van Creveld syndromes 225
Endocrine pancreas 409
Endomitosis 22
Enterobacter aerogenes 419
Enzymatic pathways, disorders of 91
Ependymoma 222
Epinephrine 185
Epithelial membrane antigen 252
Epsilon aminocaproic acid 172
Epstein's syndromes 159
Erysipeloid eruption 432
Erythroblast transformation 23
Erythroid cell maturation 52
antenatal 58
developmental 49
embryonic development of 49
primitive 5
transcriptional regulation of 51
Ewing's protocol 248
Ewing's sarcoma 250
Extraembryonic yolk sac 3
F
Febrile nonhemolytic transfusion reactions 288
Fechtner's syndromes 159
Ferrous fumarate 67
Ferrous gluconate 67
Ferrous glycine sulfate 67
Ferrous succinate 67
Fetal
albumin 268
management of 294
blood
typing 76
bone marrow hematopoiesis, regulation of 5
bradycardia, transient 295
effects 64
erythropoiesis 303
gene therapy 45
germ cell tumors 254
hematological disorders 43
hereditary persistence of 39
hydrops 259
immunity 325
kell blood group 44
liver 3
myeloid series 299
stem cell therapy 44
umbilical cord 29
Fetomaternal transfusion 59
Fibrinolytic pathway 125
Fibronectins 333
Fibrosis, cystic 128
Fils syndrome 377
Fistula, arteriovenous 25
Flavonoids 225
Fluorescent in situ hybridization 226
Folic acid deficiency 67
Free fatty acids 268
Furazolidone 95
G
Gamma granule deficiency 175
Gamma-glutamyl carboxylase 124
Gamma-thalassemia 97
Ganulocytes, development of 7fc
Gaslini diagnostic score 432
Gaucher-type histiocytes 185
Germinoma 257
Giardia lamblia 369
Gliomas, low-grade 222
Globin loci 49
Glomerulonephritis, membranoproliferative 418
Glucose phosphate isomerase deficiency 96
Glycolipids 333
Gonadal germ cell tumor 256
Granule deficiency 201f
Graves’ disease 334
Griscelli disease 208
H
Headache 434
Heat instability test 99f
Hemangioblasts 21
Hemangioendothelioma, infantile hepatic 230
Hematological disorders, inherited 38
Hemophagocytes 396f
Hemophagocytic lymphohistiocytosis
genetics of 392
primary 391f
revised 399t
secondary 390t
treatment of 400
Hemophagocytosis 404
Hemorrhage
antenatal 176
gastrointestinal 176
intrathoracic 25
periventricular 284
transplacental 83
Henoch-Schönlein purpura 418
Hepatic hemangioma, asymptomatic focal 231
Hexokinase deficiency 96
Hip, congenital dislocation of 255
Histiocytic disorders 226
Hodgkin's disease 272
Hodgkin's lymphoma 404
Homovanillic acid 242
Human
chorionic gonadotropin 258
megakaryocyte growth 24
platelet antigen 179
protein C 139
T-cell lymphotropic virus 359
Hyperleukocytosis 226
Hyperlipidemia 396
Hypertriglyceridemia 403
Hypoparathyroidism 409
Hypoprothrombinemia 123
Hypospadias reflux 255
Hypothalamus 65
Hypothryoidism 409
Hypoxic ischemic encephalopathy 309
I
Ichthyosiform 432
Immune
cells 327
deficiency syndromes 390
dysregulation 388
neutropenia 193
aberrations of 317
function of 317
thrombocytopenia 371
Infantile cancers, management of 218
International Society of Pediatric Oncology Liver Tumor Study Group 233
Interstitial lung disease 431
Intestinal atresia, multiple 377
Intrauterine
platelet transfusion 295
Ischemia, hypoxic 135
Isovaleric acidemia 159
Itch deficiency 408
L
Lactation 64
Langerhans cell histiocytosis 226
Lectin-binding pathway deficiency 420
Leiomyosarcoma 252
Leishmania 400
Leucine-rich repeat containing receptors 320
Leukemoid reaction 186
Leukoplakia 107f
Liley's chart 27
Lipoblastoma 253
Lipodystrophy 432
Lipoprotein 143
extrarenal rhabdoid tumor of 235f
failure 177
hematopoiesis 4
regulation of 5
infantile choriocarcinoma of 234
tumors, benign 235
Lymphopenia 344
Lymphopoiesis, primary 354f
M
Macroglobulinemia 112
Marrow failure syndrome 209
Mast cells 330
Maternal
management of 77
antibody testing 76
antithyroid-stimulating hormone receptor 334
autoantibodies 175
blood grouping 76
hemorrhage 176
hypertension 348
hypoferremia 65
immune thrombocytopenic purpura 175
rash 176
systemic lupus erythematosus 175
May-Hegglin syndrome 163
Measles 363
Medulloblastoma 222
Megakaryoblastic leukemia, acute 219
Metabolic disorders 159
Metamyelocytes 89f
Methylene tetrahydrofolate reductase polymorphism 143
Microbicidal metabolism, disorders of 201
Microphthalmia 103
Migratory erythema 432
Molluscum contagiosum 377
Mononuclear cells 14
Montreal platelet syndrome 159
Morbilliform rash 432
Multiple coagulation factors, hereditary deficiency of 124
Mumps 363
Myalgia 434
Mycobacteria 361
Mycobacterium avium 342
Mycobacterium bovis 339
Myelocytes 89f
Myelofibrosis 5
Myelogenous leukemia, acute 159
Myeloma, multiple 112
Myelopoiesis 299f
N
Nalidixic acid 95
Naphthalene 95
Nausea 434
Necrosis 245
Neonatal
acute lymphoblastic leukemia 227f
alloimmune
neutropenia 207
bone marrow 15
cell-mediated responses 331
erythropoiesis 303
gastrointestinal tract 327
granulocytes 16t
hemolysis 88
hemophagocytic lymphohistiocytosis 399
hemostasis 10
immune
neutropenia 193
system 337
infections 155
jaundice 91
development of 225
malignant 232
malignancies 270
megakaryopoiesis 153
myeloid series 299
necrotizing enterocolitis 328
neutropenia 195
causes of 189t
immune mediated 349
neutrophils 15
quantitative insufficiency of 15
onset multisystem inflammatory disease 432
polycythemia 111
polymorphonuclear leukocyte 300
soft tissue sarcomas 250
causes of 154
distribution of 270t
Wilms’ tumor 246
antibodies 194
chemotaxis 350
development of 14
extracellular traps 16
disorders 204t
immunodeficiency syndrome 186
morphology 207
number, disorders of 348
progenitors, infection of 211
reference range of 183f
Nodular regenerative hyperplasia 371
Non-Hodgkin's lymphoma 404
Nonrhabdomyosarcoma soft tissue tumors 253
North American Survey 104
Northern Neonatal Nursing Initiative Trial Group 283
Novel erythropoiesis stimulating protein 310
P
Paralytic poliomyelitis, vaccine-associated 342
Parathyroid glands 409
Partial volume exchange transfusion 114
Patau syndrome 161
Pegademase bovine 363
Pelger-Huët anomaly 186
Pentraxins 319
Perinatal sepsis 155
Periodic fevers 430
Periodontitis, juvenile 350
Peyer's patches 190
Pharyngitis 430
Phenazopyridine 95
Phosphatidylserine 166
Phosphofructokinase deficiency 96
Phosphoglycerate kinase deficiency 96
Phosphorus, deficiency of 67
Placenta previa 176
Placental red cell transfusion 112
Plasminogen activator inhibitor deficiency 175
Plasmodium falciparum 90
Plasmodium vivax 90
antibody-induced platelet dysfunction 167
developmental
aspects of 19
pathway of 21fc
disorders, severe 172
formation 22
function 20
test 170t
granule disorders 164
neutralization procedure 121
nucleotide assays 168
number 167
production, exogenous stimulation of 24
receptors, disorders of 166
structure 20
Pleomorphic spindle cell neoplasm 251t
Pneumatocele 381
Pompe disease 45
Portal hypertension, idiopathic noncirrhotic 371
Portal vein thrombosis 144
diseases 366
Properdin deficiency 419
Prostaglandins 334
Prosthetic cardiac valves 144
Protease inhibitors 333
Pseudoxanthoma elasticum 163
Psoriasis 361
Purpura fulminans 139f
Pyknocytosis, infantile 90
Pyridoxine, deficiency of 67
R
Raccoon eyes 239
Radius syndrome 160
Ranitidine 211
Refractory disease 403
Renal vein thrombosis 177
Respiratory distress syndrome 179
Respiratory syncytial virus 339
Retinocytoma 264
Retinoma 264
Rh blood group system 74
Rh hemolytic disease 82
Rh isoimmunization 74
Rhesus disease, severe 176
Rheumatoid arthritis, juvenile 390
Rotavirus 363
S
Scalp 409
Schimke immunoosseous dysplasia 381
Schimke syndrome 377
Sclerosing cholangitis 129
Scott syndrome 166
Sebastian's syndromes 159
Selective immunoglobulin A deficiency 372
Seminoma 257
Septicemia 348
Serositis 361
Serratia marcescens 439
Serum alfa-fetoprotein values, normal range of 258t
Serum glutamic pyruvic transaminase 396
Simpson-Golabi-Behmel syndrome 245
Sjögren syndrome 361
Spina bifida 255
Spindle cell sarcoma, nonpleomorphic 252t
Spleen 331
Splenic follicles 190
Staphylococcus epidermidis 210
Stomach 409
Stomatitis, aphthous 430
Stomatocytosis, hereditary 94
Storage pool diseases 169
Stress erythropoiesis 5
Sulfacetamide 95
Sulfamethoxazole 95
Sulfanilamide 95
Sulfapyridine 95
Syndromic thrombocytopenia, causes of 159
T
activation 322
defects 443
evaluation 362
function 362
lineage development 357f
lymphopenia, Secondary 442
Tertiary lymphoid organs 318
Tetralogy of Fallot 185
Thiazides 211
Thiazolesulfone 95
amegakaryocytic 185
Thromboembolism, prophylaxis of 149
Thyroid gland 409
Tissue plasminogen activator 8
Tonsillar fossa 369f
Total iron binding capacity 68
Toxoplasmosis 226
Transfusion transmitted infections 296
Triose phosphate isomerase deficiency 96
Turner syndromes 225
Typical radial ray deformity 104f
U
United Kingdom Dyskeratosis Congenita Registry 10
Uridine diphosphoglucuronosyl transferase gene 95
Urinary plasminogen activator 8
V
Varicella zoster virus 382
Vascular endothelial growth factor 5
Vasculitis 361
Vein, umbilical 30
Vesicoureteric reflux 255
Vibrio cholera 333
Video-assisted thoracic surgery 259
Vitamin
A, deficiency of 67
B12 68
C, deficiency of 67
K 124
K dependent
coagulation factors 174
proteins, carboxylation of 129
K, role of 129
Vitiligo 409
Vomiting 434