Editors GN Mahapatra
Senior Consultant and Head
Department of Nuclear Medicine PET-CT, SPECT-CT SevenHills Hospital Executive President, WCCICC–2017
Mumbai, Maharashtra, India
PC Manoria Director
Manoria Heart and Critical Care Hospital
Bhopal, Madhya Pradesh, India
Diwakar Jain
Professor of Medicine Director of Nuclear Cardiology New York Medical College Westchester Medical Center
Valhalla, New York, USA
Forewords Daniel S Berman,
Jagat Narula
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Cardiac Imaging Update 2017
First Edition: 2017
9789386322937
fm5Contributors
- Aamish Kazi
- Junior Consultant
- Picture This by Jankharia
- Mumbai, Maharashtra, India
- Abhiram GA
- Department of Nuclear
- Medicine
- PGIMER, Chandigarh, India
- AK Pancholia
- Head
- Department of Medicine, Clinical and Preventive Cardiology
- Arihant Hospital and Research Center
- Indore, Madhya Pradesh, India
- Anirban Mukherjee
- Department of Nuclear Medicine
- Eastern Diagnostics
- Kolkata, West Bengal, India.
- Anitha G
- Arrhythmia—Heart Failure Academy
- Department of Cardiac Electrophysiology and Pacing
- The Madras Medical Mission
- Chennai, Tamil Nadu, India
- Asha Moorthy
- Lead Consultant
- CG Heart Institute
- Super-Speciality Hospitals
- Chennai, Tamil Nadu, India
- Ashwani Sood
- Associate Professor
- Department of Nuclear Medicine
- PGIMER, Chandigarh, India
- Bhavin Jankharia
- Consultant Radiologist
- Picture This by Jankharia
- Mumbai, Maharashtra, India
- BK Das
- Director and Chief
- Department of Nuclear Medicine
- Utkal Institute of Medial Sciences
- Bhubaneswar, Odisha, India
- BR Mittal
- Professor and Head
- Department of Nuclear Medicine
- PGIMER, Chandigarh, India
- Chetan D Patel
- Professor
- Department of Nuclear Medicine
- All India Institute of Medical Sciences
- New Delhi, India
- Debabrata Dash
- Senior Interventional Cardiologist
- Thumbay Hospital
- Al Nuaimiyah, Ajman, UAE
- Diwakar Jain
- Professor of Medicine
- Director of Nuclear Cardiology
- New York Medical College
- Westchester Medical Center
- Valhalla, New York, USA
- Eike Nagel
- Head
- Department of Interdisciplinary
- Cardiovascular Imaging
- DZHK Center for Cardiovascular Imaging
- University Hospital Frankfurt
- Frankfurt, Germany
- Gawri Sankar
- Senior Resident
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Lucknow, Uttar Pradesh, India
- GN Mahapatra
- Senior Consultant and Head
- Department of Nuclear Medicine
- PET-CT, SPECT-CT SevenHills Hospital
- Mumbai, Maharashtra, India
- Executive President, WCCICC–2017
- HK Chopra
- Chief Consultant Cardiologist
- Moolchand Medcity
- New Delhi, India
- IB Vijayalakshmi
- Professor
- Department of Cardiology
- PSSMY Super-Speciality Hospital
- Victoria Hospital Complex
- Bangalore Medical College and Research Institute
- Bengaluru, Karnataka, India
- Jagat Narula
- Professor
- Department of Medicine and Radiology
- Icahn School of Medicine at Mount Sinai
- Mount Sinai, New York, USA
- Jain T Kallarakkal
- Interventional Cardiologist
- St Mary's Hospital
- Thodupuzha, Kerala, India
- Jamshid Maddahi
- Director
- UCLA School of Medicine
- Los Angeles, California, USA
- Johann Christopher
- Consultant Cardiologist
- Director of Imaging
- Care Hospital
- Hyderabad, Telangana, India
- Meera Venkatesh
- IAEA, Vienna, Austria
- MS Hiremath
- Director
- Cardiac Cath Lab
- Ruby Hall Clinic
- Pune, Maharashtra, India
- Mudalsha Ravina
- Senior Resident
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Lucknow, Uttar Pradesh, India
- Mythri Shankar
- Senior Consultant
- Department of Nuclear Medicine
- Cytecare Cancer Hospitals
- Bengaluru, Karnataka, India
- N Ramamoorthy
- Former Head
- Radiopharmaceutical Division
- BARC-DAE
- Mumbai, Maharashtra, India
- Navin C Nanda
- Professor
- Department of Medicine
- Director
- Heart Station/Echocardiography
- Laboratories
- Neel Bhatia
- Associate Consultant
- Department of Noninvasive Cardiology
- BLK Super-Speciality Hospital
- Delhi, India
- Nitin Yadav
- Junior Resident
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Lucknow, Uttar Pradesh, India
- Om Tavri
- Consultant Radiologist
- Asian Heart Institute
- Mumbai, Maharashtra, India
- Oma Shankar
- Chief Technologist and RSO
- Department of Nuclear Medicine
- Utkal Institute of Medical Sciences
- Bhubaneswar, Odisha, India
- Padmakar V Kulkarni
- Department of Radiology
- The University of Texas Southwestern
- Medical Center
- Dallas, Texas, USA
- Pankaj Manoria
- Chief Interventional Cardiologist
- Manoria Heart and Critical Care Hospital
- Bhopal, Madhya Pradesh, India
- Parang Sanghavi
- Junior Consultant, Picture This by Jankharia
- Mumbai, Maharashtra, India
- PC Manoria
- Director
- Manoria Heart and Critical Care Hospital
- Bhopal, Madhya Pradesh, India
- Peeyush Jain
- Head
- Department of Preventive and Rehabilitative Cardiology
- Fortis Escorts Heart Institute
- New Delhi, India
- Piyush Manoria
- Sr Resident
- Department of Gastroenterology
- Sri Aurobindo Institute of Medical Sciences
- Indore, Madhya Pradesh, India
- Prasanta Kumar Pradhan
- Professor
- Department of Nuclear Medicine
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Lucknow, Uttar Pradesh, India
- Priya Chudgar
- Consultant Radiologist
- Asian Heart Institute
- Mumbai, Maharashtra, India
- René RS Packard
- Department of Medicine (Cardiology) and Department of Molecular and Medical
- Pharmacology (Nuclear Medicine)
- UCLA School of Medicine
- Los Angeles, California, USA
- Sameer Shrivastava
- Director
- Noninvasive Cardiology
- Fortis Escorts Heart Institute
- New Delhi, India
- Sanjay Gambhir
- Head
- Department of Nuclear Medicine
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
- Lucknow, Uttar Pradesh, India
- Satoshi Nakatani
- Consultant Cardiologist
- Division of Functional Diagnostics
- Department of Health Sciences
- Osaka University Graduate School of Medicine
- Yamadaoka Suita
- Osaka, Japan
- Shrikant Solav
- Consultant
- Department of Nuclear Medicine
- SPECT Lab
- Pune, Maharashtra, India
- SK Parashar
- Superintendent
- SKS Medical College
- Bhopal, Madhya Pradesh, India
- Sudatta Ray
- Consultant
- Department of Nuclear Medicine
- Utkal Institute of Medical Sciences
- Bhubaneswar, Odisha, India
- Tommaso D’ Angelo
- Section of Radiological Sciences
- Department of Biomedical Sciences and Morphological and Functional Imaging University Hospital
- Messina, Italy
- Ulhas M Pandurangi
- Head Arrhythmia–Heart Failure Academy
- Department of Cardiac Electrophysiology and Pacing
- The Madras Medical Mission
- Chennai, Tamil Nadu, India
- Viney Jetley
- Associate Director
- Department of Cardiology
- Senior Interventional Cardiologist
- Fortis Escorts Heart Institute
- New Delhi, India
Over the past several decades, the field of cardiac imaging has developed at a remarkable rate. Powerful noninvasive tools for the diagnosis and management of patients with cardiovascular disease have come up. Noninvasive imaging of the heart has become a central component in the evaluation of nearly all cardiac patients. It is important for a practicing physician, using these methods, to be knowledgeable regarding the fundamentals, strengths and weaknesses of the methods, as well as of the evidences supporting their clinical use. In this book Cardiac Imaging Update 2017, GN Mahapatra has enlisted experts in all of the imaging fields as well as in specific clinical cardiology fields of the current interest, to write the chapters that cover the full range of clinical cardiac imaging and its applications, and the current topics in clinical cardiology, focusing on how the information derived can be used in clinical decision-making and patient management.
Section 1—Cardiac Imaging is devoted to noninvasive imaging. For echocardiography, it focuses on the major areas of strength with chapters on endocarditis, aortic stenosis, heart failure, and cardiomyopathy. From the technological standpoint, recent developments in speckle tracking are covered in a separate chapter. A chapter covers the applications of cardiovascular magnetic resonance (CMR), while another discusses the relative roles of CMR and cardiac CT. The book then delves deeply into recent developments on the use of nuclear scanning for assessment of the patients with known or suspected coronary artery disease and myocardial viability. Regarding SPECT and PET, a chapter covers how myocardial perfusion imaging (MPI) with these methods, is applied. Specifically, regarding PET, a chapter deals with rubidium-82 for MPI, which can be performed without the need for a cyclotron at a facility, which is dealing with the added value of quantitative myocardial perfusion reserve with PET MPI tracers. How myocardial viability imaging with PET combined with SPECT—an approach that could be widely available—can be performed even in sites that do not have access to a PET perfusion tracer, by combining the use of F-18 fluorodeoxyglucose (FDG) for metabolism, the standard PET tracer used for assessing cancer, with the standard SPECT agents that are used for MPI. This is followed by a chapter which that on the question as to how myocardial viability imaging applies to clinical practice, an area of controversy given the results of recent multicenter trials. Two chapters explore novel tracers and their evolution. The potential application of assessing cardiac dyssynchrony with nuclear medicine procedures and their possible applications in guiding cardiac resynchronization therapy, is also covered. The book then explores invasive approaches used for assessment of coronary plaque and flow physiology. In Section 2—Clinical Cardiology, consideration of several areas of current interest in cardiology outside of imaging, is explored. Overall, clinicians performing cardiac imaging as well as those who utilize these techniques in practice, will find the book very useful to provide a comprehensive update of the status of the clinical applications of the imaging approaches as well as an update of important issues of clinical cardiology.
Daniel S Berman MD FACC
Professor
Department of Medicine
UCLA School of Medicine
Los Angeles
Chief
Department of Cardiac Imaging and Nuclear Cardiology
Cedars-Sinai Health Institute
Los Angeles, California, USA
fm9Foreword
A compendium of chapters written by the stalwarts in the field of cardiovascular imaging is being released on the eve of the uniquely conceived, one of its kind in India, imaging conference—First World Congress on Cardiac Imaging and Clinical Cardiology–2017 (WCCICC–2017). It is a unique blend of cardiovascular diagnostic and prognostic imaging and the appropriateness of the clinical and procedural management. The content of the Congress and hence the collection of chapters included in this book, strive toward an ecumenical approach to imaging; promoting cooperation between the, now distinct, often competing, and parochially biased, imaging disciplines. This Congress and chapter collection, actively seek to change the thinking from imaging as a destination to imaging as a patient-care enhancer. It serves as a soapbox to encourage the development of an integrated cardiovascular imaging subspecialty.
These are exciting times for cardiovascular imaging. Rapid advances in technology have opened up a bewildering array of clinical applications. Although imaging is one of the major discoveries of the last millennium, and is growing at a rapid pace, there is intense scrutiny of its benefit and extensive controversy over who can best deliver it. The carefully selected chapters have exploited the uniqueness of each imaging modality and identified its strengths to best optimize the clinical care. Dr GN Mahapatra and colleagues are to be congratulated for bringing the best topics of the Congress together, and hope that the readers will be as thrilled as the authors are, and that whatever be your area of interest, this compendium has something for each one of you.
I wish the Congress as well as this collection every success!
Jagat Narula MD PhD MACC
Philip J and Harriet L Goodhart Chair in Cardiology
Professor, Medicine and Radiology, Icahn School of Medicine
Chief of Cardiology, Mount Sinai West and St Luke's Hospitals
Associate Dean, Arnhold Institute for Global Health
Director, Cardiovascular Imaging, Mount Sinai Health System
Mount Sinai, New York, USA
Editor-in-Chief, Journal of the American College of Cardiology—Imaging
Executive Editor, Journal of the American College of Cardiology
fm11Preface
Cardiac Imaging Update 2017 is a unique attempt encompassing an amalgam of cardiac imaging and clinical cardiology. In the era of multiple super-specialties, it is an excellent step for maintaining unity among diversity in the field of medical sciences. This cohesiveness is, indeed, the need of the hour.
In this book, a talented group of experts, who have excelled in their fields, have provided the in-depth information on the topics covered.
The book begins with Section—1: Cardiac Imaging, and highlights current concepts of echocardiography, CT, CMR, PET-CT, SPECT, and multimodality imaging, in various cardiovascular diseases. Chapters have also been dedicated to the current interventional imaging techniques such as optical coherence tomography.
Section—2: Clinical Cardiology has chapters on emerging therapies such as PCSK9 inhibitors and DOACs in atrial fibrillation, STEMI, statin intolerance, and sudden cardiac death, etc.
We are sure the book will be of immense value to the postgraduates, physicians and specialists and will find a permanent place on their desk.
GN Mahapatra
PC Manoria
Diwakar Jain