A
Absolute neutrophil count 377
Abuse, newer drugs of 317
Acetate 75
Acetoacetate 510
acute metabolic 510
correction of 269
intraoperative metabolic 267
pathophysiology of 508
reversing 304
Actinomyces 134
Activated clotting time 515
Actoxumab 178
Acute cardiovascular syndrome 65
Acute encephalopathic viral syndrome 214
Acute myocarditis 134
clinical presentation 135
diagnostic workups 135
management 136
pathogenesis 134
Acute respiratory distress syndrome 9, 11, 21, 27, 35, 37, 37f, 38fc, 46, 49, 56, 59, 61, 62t, 64, 99, 107, 122, 123, 125, 213, 225, 322, 374, 381, 493, 506, 530
pediatric 530
Acute right ventricle failure, causes of 123t
Acyclovir 59
Acyl-homoserine lactone 178
Adenovirus 134
Adequate nutritional supplementation 489
Adequate perfusion, maintenance of 301
Adjuvant therapy 505
Adult advanced cardiovascular life support 130
Adult intensive care units 189
Advanced cardiac life support 128
Advanced glycation end-products 63
Advanced life support, pediatric 503
Agonal gasps, identification of 128
Agranulocytosis 316
Air hunger 47
abnormality, chronic 224
anatomical difficult 19
assessment 19t
guidelines 24
protocols 24
optimize 143
higher 61
resistance 51
Alarm systems, modifying 444
Alcohol intoxications 322
Aldosterone antagonists 209
Alkali therapy 268
Alkalinization therapy 320
Allopurinol 377
All-trans retinoic acid 373
Alprazolam 317
Alteplase 253
Alveolar pressures, targeting 38
Alzheimer's disease 250
Ambler class C beta-lactamase 167
American Academy of Pediatrics 422
American Association of Critical Care Nurses 405
American College of Surgeons 300
American Gastroenterological Association 345
American Society of Parenteral and Enteral Nutrition 358
American Thoracic Society 181
Amikacin 161
Amiloride 440
Amino acids 316
Aminocaproic acid 303
Aminophenol 311
Amlodipine 321
Ammonia, clearance of 340
AmpC enzyme 166
Amyl nitrite 311
Anaerobic reserve, low 381
Anasarca 93
Ancillary tests 522
Angle closure glaucoma, acute 316
Anidulafungin 225
Aniline dye 311
Ankle 357
Anoxic brain injury 143
Antemortem interventions 429
Anthropometric measurements 358
Antibacterial therapeutic agents, alternative 178
against gram-negative bacteria 178
against gram-positive bacteria 177
duration of 181
judicious use of 172
options 177
resistant bacteria, genotype of 167t
sensitive enteric gram-negative bacilli 68
treatment, tailoring 166
Antifibrinolytic medications 303
Anti-inflammatory pathways 274
Antioxidants 16
Antipsychotic drugs 324
Anti-psychotics 315
Antiviral therapies 137
Aorta, abdominal 329
Aortic graft prosthesis, treatment of 175
Aortic perforations 32
Apixaban 440
Apnea testing 522
Arachnoiditis, chemical 161
Arterial catheterization 470
Arterial system, dilatation of 103
Ascorbic acid 191f
Aspergillosis, invasive 223
Assessing global oxygenation 109
Asthma 318
Ataxia 161
Atelectasis 49
Atelectrauma 35
Atrial septal defects 123
Audience engagement 470
Audio-video support 472
Augment tissue perfusion 299
Augmentative communication 389
Autism 218
Autoimmune disorders 218
Automated external defibrillator 128
Automated objective pupillometers, development of 250
Average volume assured pressure support 44
Avian influenza 213
Axonal breakage 259
Azalides 161
Azithromycin 161
Azoles 225
B
Baby lung concept 46
Bacteremia 166
Bacteria, gram-negative 178
Bacterial cell surface 174
Bacteroides 216
Bag-mask ventilation 19
Balanced target enzyme inhibition 177
Balloon angioplasty 255
Barbiturate 146
Basal metabolic rate 435
Basic life support 130
Bayesian networks 444
Bell's palsy 162
Benzocaine 311
Beri-beri 134
Beta-hydroxybutyrate 510
Bevacizumab 374
Bezlotoxumab 178
Bifidobacterium 216
Bilevel positive airway pressure 26
Biliary excretion, undergo 491
Biliary loss 490
Biotin 491
Biotrauma 35
Blastomyces 134
Blautia 216
Bloating, abdominal 349
Blood 171
brain barrier 162
component therapy 524
consumption, assessment of 303
count, complete 68
cultures 204
flow 327
fresh 363
glucose monitoring 483
frequent 483
systems, first-generation 481
group
A 365
O 365
loss
acute 380
severe 328
management, patient 383
oxygenation of 515
autoregulation of 327
diastolic 327
implications on 328
lower limit of 328
maintaining 327
management of 87
upper limit of 329
products, administration of 523
sugar 477
complications of 365t
Body mass index 101
Bony interference 31
Bordetella pertussis 500
Borrelia 134
Bortezomib 375
Brachial plexus 30
builds perception 467
computed tomography 148
confirm 521
declaration 520
determination 521
pediatric 523
etiology of 520
guidelines 523
pediatric 520
imaging 259
injury
acute irreversible 210
hypoxic ischemic 520
ischemia, models of 248
natriuretic peptide 139
tissue
oxygen partial pressure 244
oxygenation 243
Brainstem functions 520
Bromism 316
Bronchial intubation 49
Bronchitis 182
Bronchoconstriction 51
Bronchospasm 321
Burkholderia cepacia 218
Burns 61
Busulfan 374
C
Cairo-Bishop classification 376
Cancer 223
Cannabinoids 318
Capecitabine 375
Capillary refill time 108
Carbohydrates 491
Carbon monoxide 134
Carbonic acid buffer 508
Cardiac catheterization laboratory 143
Cardiac filling pressures 56
Cardiac function, impaired 289
Cardiac resynchronization therapy 85
Cardiac surgery 382
Cardiac tamponade 32
Cardiac transplantation 137
Cardiothoracic surgery, high-risk 5
Cardiotoxic drugs 144
Cardiotoxicity 373
Cardiovascular
dysfunction 499
event, major adverse 132
hemodynamics, deterioration of 65
management 516
manifestations 321
organ dysfunction 499
signs 485
symptoms 315
Cardioverter defibrillator, implanted 147
Care dilemma, direction of 436
Caspofungin 225
Catabolism syndrome 216
Cathinones, substituted 317
Causation mediation analysis 38
Cefaclor 134
Cefalexin 160
Cefepime 160
Cefiderocol 179
Cefoperazone 160
Cefotaxime 160
Ceftaroline 177
Ceftolozane 178
Ceftriaxone 160
Cells, malfunction of 369
Central venous
Cerebral
blood flow 242
monitoring 243
circulation 14
oxygen saturation, measure 145
oxygenation 244
monitoring of 242
sodium wasting 210
Chandipura virus 215
Chemotherapeutic agents 373
Chemotherapy complications, managing 373
Chest
cardiac massage 128
depth of 129
feedback 130
rate 129
pain 33
radiography, using 154
recoil 130
wall elastance 38
China coronavirus, novel 214
Chlamydia 172
Chlorates 311
Chlordiazepoxide 317
Chloroquine 311
Cholangiopancreatography, endoscopic retrograde 344
Chordae tendineae 122
Chromium 491
exacerbations of 123
Churg-Strauss syndrome 134
Circulation, coronary 380
Cirrhosis, decompensated 224
Cisplatin 375
Citrobacter 166
Clarithromycin 161
Clenbuterol 316
Clinical pulmonary infection score 181
Clomipramine 320
Clotting factors, dilution of 518
Clozapine 134
Coccidioides 134
Cochrane analysis 14
Cognitive behavioral therapy technique, trauma-focused 424
Colchicine 134
Colitis, infectious 375
Colonized central venous catheter 171
Colonoscopy 221
Colony forming unit 223
Combination therapy 204
Compensation, homeometric 122
Computed tomography
angiography 238
perfusion imaging 239f
pulmonary
angiogram 147
angiography 65
scan 236
Consciousness, loss of 259
Continuous blood glucose monitoring 481
Contrast enhanced computed tomography 336
Coprococcus 216
Core-periphery temperature gradient 109
Corneal reflex 148
Coronoviruses 214
Corynebacterium diphtheriae 134
Coxiella burnetii 134
Cranial nerve toxicity 161
Craniotomy, decompressive 529
Cricothyrotomy 470
Crimean-congo hemorrhagic fever 214
Crisis capacity 308
Critical care 213
challenges of 452
clinicians 423
outreach team 407
intervention and communication 410
scope of service for 408
pharmacists assist clinicians 456
role of 308
triage policies 309
Critically ill score, nutrition risk in 358
Cryoprecipitate 518
Cyanmethemoglobin 312
Cyanosis, presence of 30
Cyclical inflation-deflation 35
Cystic fibrosis 183
Cytarabine 375
Cytochrome oxidase 192
Cytomegalovirus 365
D
Dabigatran 440
Dallas criteria 134
Daunorubicin 375
Dazoxiben 59
Debacker score 83
Debriefing, structural elements of 471
Decolonization 172
Decongestants 316
Deep seated abscess, management of 183
Delafloxacin 177
Dementia 436
Dendritic cells 229
Desomorphine 317
Dexrazoxane 378
Dextromethorphan 315
Dextrose solutions 479
Diabetes mellitus 134
Dialytrauma 277
Diaphragmatic thickening fraction 53
Diastolic arterial pressure 99
Dichotomy 14
Diethylhexyl phthalate 364
Digestive decontamination 172
Digital subtraction angiography 239
Digoxin 144
Dilemma, secondly 363
Diltizem 315
Diplopia 161
Direct oral anticoagulants 32
Disability, causes of 253
Disaster 305
and casualties, types of 306
intensivists perspective of 307fc
location of 306
management 305
evolution of 306
medical resource planning during 309
planning 308
risk management 306
victims of 309
Discomfort, abdominal 220
Disseminated intravascular coagulation 325
Dissolve thrombus 31
Distension, abdominal 349
Diuretics, role of 96
Dofetilide 440
Doripenem 160
Doxorubicin 375
Drain pleural effusion 56
Dry mouth 321
Duloxetine 440
Duplex sonography 31
Dynamic tests 102
Dysoxia, cellular 113
Dysphagia 161
Dyssynchrony 47
E
Early warning system 460
Ebola virus 214
Ebstein anomaly 123
Echinococcus 134
Echovirus 134
Eclipse 527
Edema, peripheral 93
Ejection fraction, reduced 140
Elastic tissues 36
Electromyography 41
Embolism 494
Emergency
coronary intervention 144
endotracheal intubation, complications of 19b
mass critical care 307
medical services 129
medicine team 432
room 143
Emotional problems 148
Emphasis 129
Emphysema 58
Empyema 183
End inspiratory lung volumes 56
End of life care process pathway 438
Endomyocardial biopsy, application of 134
Endoscopic ultrasound-guided transmural drainage 345
Endothelial activation 210
Endotoxemia 84
Endotracheal aspirate 171
Endotracheal tube 18
End-stage liver disease score 341
Enemas 350
Enoxaparin 440
Enterococci 182
Enterocolitis 375
Entner-Doudoroff pathway, component of 75
Environmental destruction 305
Ergotrauma 36
Erlotinib 375
Ertapenem 160
Erythromycin 161
Erythropoietin, human 370
Esophageal balloon catheter 37
Esophagitis 375
Estimate glomerular filtration rate 283t
Ethylene glycol 322
Eubacterium 216
Eukaryotes 16
Euphoria, sense of 316
European Cooperative acute Stroke Study 235
Evelyn-Malloy method 312
Everolimus 375
Ex situ perfusion 431
Expiratory positive airway pressure 43
Extensively drug-resistant, emergence of 165
Extracorporeal
circuit 516
organization 518
contraindications of 515t
indications of 513t
parameters 515
pediatric 518t
scope of 513
methods 130
organ support 206
oxygenation techniques 430
support 475
Extrapyramidal syndrome 161
Extravascular catheter migration 55
Eyeballing 124
F
Facemask, simple 8
Faecalibacterium prausnitzii 216
False alarms, reducing 443
Famotidine 440
Febuxostat 377
Ferric carboxymaltose 370
Fiberoptic bronchoscope 18
Fiberoptic ratiometric fluorescent analyzer method 284
Fibrinogen concentrates 303
Fidaxomicin 178
Filmarray respiratory panel 70
Flow volume loop 51f
Flucloxacillin 159
Fluconazole 344
effective 154
speed of 504
and electrolyte management 524
attenuated inversion recovery 240f
balance 290
bolus, volume of 504
challenge, conventional 151
collections, acute peripancreatic 342
expansion 80
losses, insensible 328
optimize 289
regime 528
removal 290
assessing for 112
clinical studies of 75
concept of 88
evidence behind 79
liberal 79
shifts, major 328
therapy 91
assessing risk of 154
complications of 149
role of 103
think of 118
volume, loss of 303
Fluoresceinyl isothiocyanate 284
Fluoroquinolones 183
Flurazepam 318
Fondaparinux 440
Food and Drug Administration 186
Fosphenytoin 527
Fresh frozen plasma 518
Furosemide 134
G
Gabapentin 440
Gamma-glutamyltransferase 319
Gamma-hydroxybutyrate 314
Gastroenteritis virus 214
Gastroenterology 333
Gastrointestinal complications 375
Gastrointestinal function 354
Gastrointestinal motility 349
Gastrointestinal symptoms 357
Gastrointestinal system 354
Gatifloxacin 161
Gefitinib 375
Gemifloxacin 161
Gene transcription 489
General severity score 461
Generalized anxiety disorder 250
Genitourinary system 499
Genomics, use of 463
Genotype, tailoring antibiotic by 165
Genotypic tests 165
Gentamicin 161
Geophysical disasters 305
Giant cell myocarditis 134
Glands, adrenal 194
Global oxygen delivery 107
accurate estimation of 281
aspects of 281
estimation
methods of 281
techniques 282t
significance of 281
Gluconate 75
Glycemic control, moderate 479
Glycocalyx performs 84
Goal-directed therapy 185
G-protein-coupled receptors, activation of 194
Granulocyte macrophage-colony stimulating factor 231
Groin vessels 514
Growth, age-related 518
Guideline-directed medical therapy 140
H
Hallucinations 315
Hallucinogenic intoxication, management of 316
Hashish 318
Hawaiian baby woodrose 317
Headache 199
Health systems 65
Healthcare 459
associated infections 170
organizations 425
provider basic life support 129
workers 306
catheterization, right-sided 93
disease
congenital 123
ischemic 321
Failure Society of America 139
first-line drugs for 209
management of 371
therapy for 139
treatment for 209
transplant rejection 134
Heat
and moisture exchange filter 44
exchanger 514
loss 278
related illnesses, categorization of 325t
stroke 324
classification 325
complications 326
differential diagnosis 325
pathophysiology 324
preventive measures 326
susceptible individuals 324
Hemofiltration, continuous venovenous 163
Hemolysis, intravascular 289
Hemolytic uremic syndrome 110
Hemorrhage 324
aneurysmal subarachnoid 383
control 299
urgent 301
secondary 303
trauma associated severe 303
Hemorrhagic complications 253
Hemostatic resuscitation, fundamental dimensions of 303
Heparin 31
Herpes simplex virus 375
High ambient temperature 325
High central venous pressure 91
High dose intravenous immunoglobulin 137
High quality pediatric studies 527
Histoplasma 134
Hormonal deficiencies 506
Hospital influences, staffing structure of 415
Human circulatory system, components of 99
Hybrid technologies 292
Hydrogen ion concentration, negative log of 73
Hydroxyeicosatrienoic acids 364
Hydroxyethyl starch trial 343
Hypercoagulable states, association of 30
Hyperinflammatory phenotype 64
Hypernatremia 511
Hyperosmolar state 270
Hyperoxemia, risks of 13
Hyperpnea 320
Hyperpyrexia 324
Hyperuricemia, mechanism of 376fc
Hyperventilation 320
Hypervolemia results 149
Hypoalbuminemia 55
Hypocalcemia, ionized 269
Hypochloremia 77
Hyponatremia 485
benign intracranial 161
duration of 328
exposure, association of 87f
intracranial 161
prediction index 116
Hypothalamic pituitary-adrenal axis 485
Hypothyroidism 57
Hypouricemic agents 377
Hypoventilation 320
Hypoxic drive, loss of 13
I
Idiopathic thrombocytopenic purpura 218
Imatinib 375
Imipramine 320
Immunomodulatory interventions, use of 230
Indian Association of Palliative Care 436
Indian Society of Critical Care Medicine 436
Indomethacin 59
Industrial accidents 305
abdominal 182
control 516
intra-abdominal 178
localized sites of 175
management 524
prevention 304
bundle interventions 172
risk of 371
site of 182
types of 182
Injury, extensiveness of 259
Inspiration, early phase of 46
Inspiratory positive airway pressure 43
Instrumental tests 522
Instruments kit 409
Intensive care
delirium screening check 436
routine 340
settings 159
Society Registry 465
unit 3, 8, 18, 23, 35, 55, 73, 80, 81, 87, 101, 110, 111fc, 113, 115, 129, 143, 149, 159, 216, 220, 223, 247, 281–283, 292, 305, 307, 308, 339, 342, 347, 349, 352, 357, 363, 366, 373, 407, 415, 427, 446, 456, 459, 463, 467, 477, 481, 486, 501
acquired immunosuppression 228
alarms 444
management of 230
technicians 444
transfusion in 363
Intensive palliative care 437
Intermittent renal replacement therapy 292
Internal preload challenge 153
Interstitial compartment 79
Intestinal failure 354
Intestinal loss 490
Intra-arterial balloon pump, options of 145
Intracellular adhesion molecule 191
Intracranial space occupying lesions 520
Intrathoracic surgery 329
Intravenous access catheters 204
Intrinsic colonization resistance 169
Inulin 282
Invasive perfusion devices 130
Iodine 491
Iohexol 282
Iothalamate 282
Irinotecan 375
deficiency 371
diagnosis of 370
functional 369
lead 134
preparation, intravenous 370
sequestration 369
substitution 369
therapy 371
Isavuconazole 225
ISBAR communication tool 411t
Ischemic damage, signs of early 236
Isoniazid 134
Isotonic intravenous fluid 499
Itraconazole 225
K
Kanamycin 161
Kawasaki disease 134
Ketamine sequence intubation 22
Ketoconazole 59
disease
acute 267
risk of chronic 272
function 518
injury 289
protection of 272
role of 207
transplant patients 170
Kinetic equations 284
King's College criteria 320
Krebs cycle 189
Kussmaul sign 93
Kyasanur forest disease virus 214
L
Lactobacillus 216
Laparoscopic surgery, robot-assisted 153
Latent class analysis 61
L-carnitine 192
Leak compensation 42
Left atrium 107
Left heart unloading 515
Legionella 172
Leukocyte count 363
Leukocytosis 502
Leukoencephalopathy 316
Levamisole 316
Levofloxacin 161
Lidoflazine 146
Life support cold ischemia 428f
Life-sustaining, withdrawal of 431
Linezolid 162
Lipid emulsion, intravenous 132
Lipoglycopeptides 177
Listeria monocytogenes 184
Local anesthetic agent 311
collapse 56
compliance 38
interactions 152
mechanics 38
parenchyma 35
recoil, degree of 56
stress, levels of 37
transplant 175
ventilation, toward safer 35
zones 46
Lyme disease 134
Lymphocytic choriomeningitis virus 215
Lymphoid organs 213
Lysogeny 175
M
Maastricht classification, modified 427t
Macocha score 19t
Macrocirculation, assessing 107
Macrovascular system discordance 83
Macula densa 74
Mallampati 19
Manganese 491
Man-made disasters 305
Mass critical care, concepts of 308f
Massive capillary leak 213
Mcconnell's sign 124
Mean absolute relative difference 482
Mean circulatory filling pressure 103
Mechanical chest compression devices 130
Mechanical energy 36
Mechanical interventions, role of 97
controlled 37f
Mechlorethamine 375
Meconium aspiration syndrome 513
Medical cardiac failure 516
Medical complications, risk of 377t
Medical oxygen 13
Medication kit 409
Membrane oxygenation 513
Mental status 108
Meropenem 160
Metabolic and respiratory acidosis 265
Metabolic control 524
Metabolic disorders 521
Metabolic disturbances 144
Metal-organic framework 190
Meteorological disasters 305
Metformin 321
Methamphetamines 314
Methyldopa 134
Methylprednisolone 524
Metoclopramide 311
Micafungin 225
Microcirculation, assessing regional 112
Microcirculatory alterations 84
Microcirculatory system 84
Microvascular flow index 83
Midazolam 516
Middle east respiratory syndrome coronavirus 213
Mineralocorticoid receptor antagonists 139
Mini nutritional assessment 357
Mitigation 306
Mitochondria 189
Mitochondrial damage 259
Moisture exchanger 49
Molecular adsorbent recirculating system 341
Molecular patterns, damage associated 500
Molecular weight heparin, low 32
Molybdenum 491
Monoclonal antibodies 374
Montpellier-ICU intubation algorithm, modified 23b
Moraxella catarrhalis 69
Morphine 318
Motion, equation of 48
Mucociliary clearance 224
Mucormycosis 134
Mucosal ischemia, signs of 336
Mucous membranes 169
Multidisciplinary critical patient 467
Multidisciplinary intensive care unit rounds 456
Multidisciplinary rounds, concept of 458
Multidrug therapy 204
Multimodality neuromonitoring 242
Multinational Association of Supportive Care in Cancer 377
Multiprofessional team 470
Murine myocarditis 134
Mycoplasma pneumoniae 134
Myeloid-derived suppressor cells 229
Myocardial depression 194
Myocardial ischemia, perioperative 381
Myocardial perfusion 327
Myocardial protection 272
Myocardium 508
Myoclonus 315
N
N-acetyl cysteine, dose of 320t
Nanoparticles 179
Naphthalene 311
Nasal decontamination 172
Nasal oxygen during efforts securing 21
Nasal pillows 42
Nasal topical decolonization 172
Nasogastric feeding 344
Nasogastric tube 219
Nasojejunal feeding 344
National early warning score 410t
National Organ and Tissue Transplant Organization 431
Natriuretic hormone 139
Natriuretic peptides 209
Natural death 436
Necrosectomy, direct endoscopic 345
Necrotic collection, acute 342
Neisseria meningitidis 500
Neomycin 161
Neonatal intensive care units 423
Neonatal population 159
Neoplasm 61
Neostigmine 350
Nephropathy, contrast-induced 31
Neprilysin inhibitor combination 139
Neuroglycopenia 320
Neuroimmune communication 194
Neurointensivists 248
Neurointerventionist 256
Neuroleptic medications 324
Neurological deficits 148
Neurological dysfunction 77
Neurological pupil index 250
Neurological sequence 521fc
Neurological systems 329
Neuromuscular blockade 161
Neuromuscular disorders 43
Neuropathy, peripheral 161
Neurotoxic effects 160
Neutropenic sepsis 377
Nicardipine 321
Nimodipine 146
Nipah virus 214
Nitrobenzene 311
Nitrofurantoin 161
Nitroglycerine 311
Nitroprusside 311
Non-alcoholic steatohepatitis 435
Non-beta-lactam antibiotic 161t
Nonbicarbonate buffers 508
Noncardiac surgery 383
Noninfectious enterocolitis 376
Noninfectious syndromes 203
Noninvasive interface 26
Nonlactose fermenting gram-negative bacilli 183
Nonmedical therapies 340
Non-neutropenic intensive care unit 223
Nonrebreather mask 20
Nonrebreathing reservoir mask 8
Nonresolving organ dysfunction syndrome 216
Nonsteroidal anti-inflammatory drug 435
Nonvolatile acids, total concentration of 73
Norfloxacin 161
Normothermic regional perfusion 430
Norovirus 214
Nortriptyline 320
Novel beta-lactam 167t
Nucleic acid detection tests 185
Numerous scoring systems 343
Nutrients, loss of 279
Nutrigenetics 347
Nutrigenomics 347
Nutritional assessment tools 357
Nutritional risk screening 358
Nutritional support 344
O
Obstructive sleep apnea 19
Occlusion pressure 52
Ofloxacin 161
Optic neuritis 161
Optic neuropathy 162
Optimal nutritional-risk 359
Organ injury, minimize 429
Organ perfuse, ex situ perfusion of 431
Organ system dysfunction 329
Organ transplantation science 433
Organic anions, metabolism of 266
Organic occlusion 338
Organizational challenges 424
Organizational factors 402
Osmotic laxatives 350
Osteomyelitis 183
Ototoxicity 161
Oxaliplatin 375
Oxazepam 317
Oxazolidinones 162
Oxycodone 318
consumption 502
continuous high-flow 21
delivery 83
devices 8fc
dissociation 380
extraction ratio 502
saturation, arterial 312
supplementation 16
toxicity, form of 14
use of supplemental 13
utilization 109
Oxygenator membrane 523
Oxygen-induced hyperoxemia dangerous, liberal 15
P
Pacemaker lead placement 30
Pancreatic fluid collections 345
Pancreatic necrosis 342
Pancreatic tissue 344
Papillary muscles 122
Paradoxical cerebrospinal fluid acidosis 270
Paradoxical pulse 93
Parainfluenza virus 172
Paresthesias 161
Parkinson's disease 218
Partial thromboplastin time 516
Passive palliative care, problem of 437
Pathogenic flora 68
Pediatric critical care 527
Pediatric intensivists 530
Pegylated liposomal doxorubicin 373
Pentoxifylline 59
Penumbral aspiration system 255
Peptic ulcer disease 316
Peptides, antimicrobial 178
Peribronchiolar edema 51
Pericardial effusion 93
Pericardial tamponade 123
Perimortem cesarean delivery 132
Peripheral nervous system 317
Peripheral neuropathy, chemotherapy induced 375
Peripheral vascular procedures 329
Periprocedural oxygenation 9
Permissive hypoxemia 16
Personal protection devices 409
Pesticide poisonings 314
Petal network 59
Phagoburn trial 175
Phagocytic assays 230
Pharmacologic thrombolysis 32
Pharmacological inotropic support 126
Phenacetin 311
Phenazopyridine 311
Phenyl ethylamines, substituted 317
Phenylbutazone 134
Pheochromocytoma 134
Phlegmasia cerulea 31
Phosphofructokinase 190
Photosynthesis, equation of 16
Physiochemistry, understanding 73
Piperazines 317
Plan-do-check-act cycle 461
Plasmapheresis, role of 530
Plasminogen activation 66
Plethysmographic variability index 113
Pleural drainage, procedural of 57
Pleural dynamics, alteration of 99
Pneumatosis intestinalis 336
Pneumocephalus 13
Pneumomediastinum 316
Poliovirus 134
Polycythemia 14
Polyene 225
Polyethylene glycol 352
Polymicrobial gene detection, presence of 186
Polymorphonuclear cells 502
Polymyositis 134
Polyneuropathy 161
Polysomnography 28
Polytrauma 417
Portal vein thrombosis 342
Portal venous system 337f
Posaconazole 225
Postanesthesia care unit 308
Postanoxic myoclonic status epilepticus 146
Postmortem organ preservation 430
Postresuscitation care algorithm 147fc
Postthrombotic syndrome 33
Posttraumatic stress disorder 60
Potassium 74
Potential long-term adverse effects 220
Potential organ donor identification 520
Potentially inappropriate drugs 439b
Precipitating cause, treatment of 144
Precision nutrition 347
Predict hypotension 115
Predictive scoring systems 10
Preexisting multisystemic disease 516
Pregabaline 440
Preintubation hypotension 24
Preload responsiveness, static indices of 151
Pressure
inspired atmospheric 16
regulated jet ventilation 23
time
product 53f
scalar 48f
volume loop 52f
Prevotella 216
Primaquine 311
Pro-brain natriuretic peptide 139
Prognostication strategy algorithm 146fc
Proinflammatory cytokines 357
Prometheus 341
Prone ventilation, physiology of 100
Prophylactic antibiotics 344
Prophylactic laxative bowel regimen 351
Prophylaxis 32
Propionate 216
Propionibacterium acnes 218
Propofol 146
Protected brush specimen 171
Prothrombin complex 303
Pseudo-obstruction, acute colonic 350
Psilocybin 315
Psychedelic substances 314
Pulmonary artery 107
constriction 125
elastance 123
hypertension
development of 92f
worsening of chronic 123
stiffness of 122
Pulmonary aspiration, risk of 349
Pulmonary blood volume 154
Pulmonary capacitance, total 122
Pulmonary disease 493
Pulmonary dysfunction, reduce 63
Pulmonary infiltrates 181
Pulmonary re-expansion edema 57
Pulmonary thromboembolism 65
Pulmonary vasculature 65
Pulmonary vasoconstriction 197
Pulmonary veno-occlusive disease 378
Pulsatility index 244f
Puncture site hematoma 32
Pupillometry, use of 251
Purpura fulminans 503
Pus, thick 183
Pyruvate dehydrogenase 191
R
Radiation exposure, risk of 31
Ranitidine 440
Rapid osmotic changes 528
Rasburicase 377
Rate and rhythm control 97
Reactive phenotype 63
Recombinant tissue plasminogen activator 494
Reflection 447
Reflux, hepatojugular 93
Refractory pleural effusion 57
Regulatory T cells 229
Rehabilitation 148
Reintubations 5
Renal acid excretion 265
Renal effects 74
discontinuation of 292
earlier 290
objectives of 289
timing of 289
triggers for starting 289
types of 290
Renal syndrome 213
Renal tubular acidosis 509
Renin angiotensin-aldosterone system 209
Research, challenges of 453
Resistance Mechanism, rapid identification of 185
Resistant mycobacterium abscess infection, treatment of 175
Resistant organisms, emergence of 288
Respiratory acidosis 269
Respiratory alkalosis 320
Respiratory compliance 37
Respiratory complications 326
Respiratory depression 321
Respiratory dysfunction 58
Respiratory function 56
Respiratory infections 171
Respiratory muscle fatigue 46
Respiratory syndrome, severe acute 307
Respiratory viral infections 213
Restrictive respiratory pathology 56
Resuscitation 14
adult cardiopulmonary 128
assessing end points of 107f
cardiovascular 66
concept of 189
control 299
effective cardiopulmonary 143
hemodynamic 189
incoherence 113t
team 128
therapeutic endpoints of 504b
Reticulum, endoplasmic 132
Retrolental fibroplasia 13
Retroperitoneal debridement, video-assisted 345
Retrospective cohort study 415
Rheumatic fever 134
Rheumatoid arthritis 134
Rickettsia rickettsii 134
Rift valley fever 214
Right ventricular
afterload, reduce 96
assist device 97
dilation 65
diagnosis of 123
management of acute 125
managing 126
signs of 93
failure 20
Ringer's acetate 73
Ringer's lactate 73
Rituximab 374
Rivaroxaban 440
Rndovascular thrombectomy, first-generation of 255
Rox index 10
S
Sacral edema 357
Sarcoidosis 134
Scalpel cricothyroidotomy 23
Scandinavia 465
Schistosoma 134
Schizophrenia 250
Scleroderma 134
Sclerosis, multiple 218
Scorpion sting 134
Seasonal affective disorders 250
Second messenger pathways, alteration of 194
Sedative-hypnotics 315
Selective serotonin reuptake inhibitor 315
Sensorium 411
bundles 205
development of 500t
diagnosis of 502
distinguishing 203
evidence of 204
places 502
recognition of 501
risk factors for 500
severe 505
signs of 501
time-bound care bundles in 419b
Septic complications 342
Septic shock 81t, 84, 87, 105, 189, 207, 267, 382, 487, 490, 499, 500, 500t, 501, 504, 505, 505t, 506
and acidosis 267t
corticosteroid therapy of 487
criteria 529
management of 502
neonatal 529
recognition of 501
severe 197
trial, vasopressin in 80
vasopressor in 79
Serious adverse events 220
clinical assessment of 107
cryptic 107
distributive 103
fluid sparing management of 528
human septic 486
hypovolemic hemorrhagic 88
management of 197
microcirculation during 84
neurogenic 89
refractory 504
vasopressor in 104
Short-chain fatty acids 216
Side-stream dark field 83
Signal transduction pathways 274
Significant failure rate 41
Silence, use of 447
Silver 1789
Simulators, broad range of 470
Single cosyntropin test 486
Single pass albumin dialysis 341
Slight blood pressure reduction 270
Slow continuous ultrafiltration 290
Slow low efficiency dialysis 322
Small bowel loops 337f
Smart artifacts filters 444
Smart comprehensive combined analyzer 444
Snake bite 134
Social media, role of 128
Social support 437
Society for Healthcare Epidemiology 170
Soft tissue 170
Solid tumors 376
Spinal perfusion pressure 89
Spironolactone 440
Splanchnic circulation 112
Splanchnic microcirculation 83
Staphylococci, coagulase-negative 182
Starvation acidosis 510
Static airway pressures 36
Static compliance 50
Static parameters 100
Sterilization 172
Steroids 486
Stewart's acid-base physiochemistry 74f
Stewart's approach 74
Stimulating immune-inflammatory response 299
Stomatitis 375
Stool softeners 350
Street pharmacists 317
Streptokinase 66
Streptomycin 161
Strongyloides 172
Subarachnoid bolts 243
Subcutaneous fat 357
Subjective global assessment 357
Suction embolectomy 255
Sudden cardiac arrest 494
Suggested action plan 352t
Supportive therapy 510
Surge capacity continuum, principles of 307
Surge continuum 308
Surge response, targets for 308
Surgery, major 328
Swollen upper limb 31f
Sympathomimetics 314
Symptomatic cardiovascular disease, stable 382
Syndrome of inappropriate antidiuretic hormone secretion 210
Syndrome respiratory failure 493
Syndromic molecular diagnostics 68
Synthetic cannabinoids 317
Systematic inflammatory response 144
Systemic autoimmune disease 134
Systemic blood pressure 65
Systemic congestion, signs of 93
Systemic heparinization 518
Systemic ischemia 143
Systemic lupus erythematosus 134
Systemic sodium levels 340
Systemic thrombolytic agents 65
T
T lymphocytes 229
Tachyarrhythmia, atrial 97
Taenia 134
Tardive dyskinesia 161
Tardive seizures 160
Task trainers 470
Technological advances, use of 444
Tedizolid 177
Tell me more 448
Temozolomide 374
Temporary closure 302
Temporary wound closure 300
Tenecteplase 253
Tetanus toxoid 134
Tetrahydrobiopterin 191
Therapeutic colonoscopy 350
Therapeutic hypothermia 523
Thermal diffusion flowmetry 244
Thiazides 134
Third fundamental property 15
Thottapalayam virus 215
Threshold levels 230
Thrombophilia 33
Thrombosis 33
Thrombotic thrombocytopenic purpura 110
Thrombus aspiration 465
Thyroid injury 23
Thyrotoxicosis 134
Thyroxine 324
Tibial infection, trauma-related 176
Ticarcillin 159
Tinnitus 320
Tobramycin 161
Tone specific alarm generation 444
Topical decolonization 172
Toxic shock syndrome 501
Toxicology 297
Toxoplasma gondii 134
Trace elements 278
Tracheostomy 23
Tramadol 440
Tranexamic acid 303
Transcranial Doppler ultrasonography 244
Transdiaphragmatic pressure 52
Transfuse intravenous iron 370
Transient psychosis 161
Transmural endoscopic drainage 345
Transnasal humidified rapid-insufflation ventilatory exchange 21
Transplant of Human Organs Act 520
Transportation accidents 305
Transudative pleural effusions 56
Trastuzumab 134
Traumatic injury 299f
Tremulousness 315
Triamterene 440
Trichinella 134
Tricuspid annular plane systolic excursion 124
Tricuspid annulus 124
Triglyceride, medium-chain 190
Triphenylphosphonium 192
Trishydroxyaminomethane 511
Trojan horse 179
Trypanosoma cruzi 134
Tryptamines 317
Tsutsugamushi 134
Tube confirmation 23
Tubular dysfunction 265
Tubular necrosis, acute 319
Tubuloglomerular feedback 74
Typhlitis 376
U
Unilateral motor posturing 242
Upper abdominal pain 342
Uremic complications, early control of 290
Uremic pleurisy 55
Uremic symptoms 289
Urinary alkalinization 377
Urinary creatinine clearance, measurement of 283
Urinary retention 321
Urogenital system 435
Urokinase 66
US Food and Drug Administration 235
V
Vaccines 134
Valvular heart diseases 123
Vancomycin 161
Vascular function 364
Vascular toxicity 373
Vasculitis, cutaneous 316
Vasoactive agents, classification of 195fc
Vasoconstriction, hypoxic pulmonary 20
Vasoplegia, pathophysiology 194
administration, early 80
decrease 80
dependent septic shock 192
therapy 194
timing of 103
use of 103
Venovenous extracorporeal membrane oxygenation 219
failure, complete 22
future of 37
low tidal volume 493
management 516
proportional assist 44
strain injury of 46
Ventilatory strategy 39
Ventricular interdependence 123
Ventricular septal defects 123
Ventricular tachyarrhythmia 321
Ventriculitis 161
Vertigo 320
Vessel occlusion, large 254
Videolaryngoscope 18
Viral hemorrhagic fever 214
Viral hepatitis 340
Viral infections, emerging 213
Viral pneumonia 513
Virtual reality 470
Vital organs, availability of 494
Volutrauma 35
Voriconazole 225
Vortex approach 24
Vulnerable population 305