100 Cases in Pulmonary Medicine Nikhil Gupta, Harsh Saxena
INDEX
Page numbers followed by f refer to figure, and t refer to table.
A
Abdominal diseases 49
Acetylene 75
Achalasia
cardia 167
primary 169
Acid-fast bacilli 8, 18, 21, 22, 39, 41, 48, 60, 74, 85, 103, 110, 119, 131, 136, 148, 155, 159, 182, 216
smear 34, 67
Acid-fast bacteria 115, 117
Acne 53
Acquired immune deficiency syndrome 16
Actinomyces israelii 83
Actinomycosis, pulmonary 83
Activated partial thromboplastin time 73
Acute pneumococcal pneumonia 68
Adenocarcinoma 308, 312
Adenosine deaminase 22, 74
levels of 330
Adenosquamous cell carcinoma 314
Agenesis 36
Allergic Aspergillus sinusitis 211, 212
Allergic bronchopulmonary aspergillosis 88, 91, 96, 171, 175, 176, 178, 180, 182, 185, 187, 190192, 211, 212f, 214
Alveolar microlithiasis, pulmonary 221
American Thoracic Society 196
Amikacin 162163, 200
Amoxicillin 44, 162, 200
Anemia 77
Aneurysm rupture 49
Angel's wing appearance 40
Angiotensin-converting enzyme 48
Anthrax 49
Anticoagulant 49
Antinuclear antibody test 353
Antiretroviral therapy 107
Antitubercular drugs 32, 104f, 129, 139, 162, 244f
dose of 107t
Antitubercular therapy 22, 23f, 24, 24f, 106
Antitubercular treatment 32, 56f, 103, 112f, 122f, 123, 124f, 126f, 134f, 136, 137f, 206, 268f, 313f
Aorta, arch of 7f
Aortography 42f
Aorto-pulmonary window, lymph nodes of 99f, 100
Apgar scores 2
Aplasia 36
Appetite, loss of 47, 125, 146, 242, 251, 277, 303, 312, 328, 330
Artery, pulmonary 86
Aspergilloma 209
pulmonary 208
Aspergillosis, invasive pulmonary 5
Aspergillus fumigatus 19, 88, 94, 171, 175, 178, 180, 185, 191, 208, 212
Aspiration pneumonia 15
Asthma 190
bronchial 34
uncontrolled 167
Atoll sign 5
Autosomal dominant polycystic kidney disease 87
B
Bacilli Calmette-Guérin 62
Barium meal study 230f, 231f
Bedaquiline 162, 163, 200
Benign fibroepithelial endobronchial polyps 258
Bilateral homogenous shadows 182f, 183f
Bilateral multiple cavitary opacities 5f
Bilateral parenchymal shadows 180f
Bilateral pleural effusion 54f, 73f, 74f, 77f, 78f
resolution of 79f
Biomass fuel 293
Bird breeder's 339
Bleeding 85
after endobronchial biopsy 253f, 281f, 311f
disorder 49
Blood counts 81
Bone
marrow biopsy 11
scan 306
Bony tumor 49
Borderline lepromatous leprosy 60, 63
Brain metastases, treatment of 326
Breast carcinoma 49
Breathlessness 10, 54, 67, 77, 88, 93, 171, 180, 216, 222, 228, 286, 312, 328, 330
progressive 14, 345, 349, 357
Bronchial carcinoid 262, 264
diagnosis of 264
treatment of 264
Bronchial disease 16
Bronchiectasis 14, 71
bilateral 16f, 91f
coexistence of 70
Bronchiolitis obliterans-organizing pneumonia 356
Bronchoalveolar lavage 5, 9, 21, 39, 67, 99, 221, 351
Ziehl–Neelsen staining of 74
Bronchodilators 81
Bronchography 174f
Bronchopulmonary neuroendocrine tumors 264
Bronchoscopy 82
Brucella 49
Burning sensation 225
C
Capreomycin 162164, 200
Carbohydrate, high 78
Carbon monoxide 340, 349
diffusion capacity for 26, 27
lung for 338
Carcinoid lung tumors 264
Carcinoid syndrome 264
chronic sequelae of 264
Carcinoid tumor 260
Carcinoma, bronchogenic 10, 49, 78
Carmustine 239
Castleman disease 56
Cavity, malignant 280f
Central bronchiectasis 184f, 191f
Cerebrospinal fluid 106, 164
Cervical lymphadenopathy 55
Cervix 326
Chemotherapy, high-dose 239
Chest computed tomography 5
Chest
computed tomography of 19, 19f, 20f, 38, 39f
contrast-enhanced computed tomography of 5, 5f, 99, 99f101f, 168f
high-resolution computed tomography of 16f, 26, 26f
infiltrates resolution of 134f, 135f, 137f, 138f
pain 1, 7, 115, 216, 242, 245, 301, 308, 312, 314, 330
right-sided 237
sudden onset of 222
radiograph 4f, 15f, 18, 19f, 26, 27f, 36, 38, 38f, 68f, 79f, 77f, 81f, 82f, 85f, 237f
roentgenogram 211f
skiagram 94f
serial 95f
wall, angiosarcoma of 49
Chilaiditi syndrome 233, 235
management of 235
Chondrosarcoma, retroperitoneal 49
Choriocarcinoma 49
Chronic obstructive pulmonary disease 28, 70, 71, 81, 93, 279, 289, 291, 295, 299, 303, 318, 324
Chylothorax 5658, 58t, 78, 79
bilateral 54, 56f, 77
Cilastatin 162, 163, 200
Cirrhosis 56
Clavulanate 162
Clavulanic acid 200
Clofazimine 62, 162, 163, 200
Combined large-cell neuroendocrine carcinoma 333
Combined pulmonary fibrosis and emphysema 357, 358
Computed tomography 2, 7, 7f, 35, 169, 218
Conglomerate mass 40
Conglomerate silicosis 38, 39
Connective tissue diseases 49
Constant pain 46
Contact dermatitis 53
Contrast-enhanced computed tomography 97, 167, 242
Corticosteroids 340
Cough 7, 14, 26, 30, 34, 41, 44, 93, 133, 146, 155, 159, 185, 219, 222, 245, 247, 249, 260, 262, 277, 286, 301, 303, 312, 314, 328, 330, 353
nonproductive 334, 345, 349
productive 70, 81, 339
recurrent 88, 256
Cushing syndrome 264
Cyclophosphamide 13
Cycloserine 121, 143, 156, 162, 163, 200
Cystic shadows 357f
Cysts, diffuse multiple 335f
D
Deficient thyroid transcription factor-1 36
Delamanid 162, 163, 200
Dengue hemorrhagic fever 49
Densities, heterogeneous 213f
Dermatitis, exfoliative 51f, 52f
Diabetes mellitus 88, 110, 266
insulin-dependent 18
type 1 18
type 2 341
Diaphragm 228f
eventration of 225, 226, 228, 231
raised dome of 118
Diaphragmatic hernia 49
Differential leukocyte count 55, 77
Diffuse reticulonodular opacities 335f
Disease-modifying antirheumatic drugs 356
Doxorubicin 239
Drug sensitive and drug resistant tuberculosis, treatment of 106
Drug susceptibility test 155, 159, 161f
Dry cough 10, 67, 99, 142, 251
Dysphasia 251, 301, 322
Dyspnea 339
progressive exertional 81
E
Echinococcus granulosus 275
Edema, pulmonary 68
Embolism, pulmonary 139
Emphysema
bilateral centrilobular 28f
paraseptal 358f
Empyema 58t
thoracis 58
Endobronchial biopsy 251, 262, 308, 314, 318
specimen, Gram's stain of 82f
Endobronchial brush 39
Endobronchial polyp 256, 257f
recurrence of 258f
Endobroncial biopsy 279
Epidermal growth factor receptor 305
Episodic breathlessness 34, 185
Erythrocyte sedimentation rate 85
Escherichia coli 86
Esophagectomy 79
Estimated glomerular filtration rate 36
Etanercept 356
Ethambutol 23, 107, 108, 112, 113, 115, 119, 123, 133, 136, 137, 155, 156, 162, 163, 195, 206, 200, 216
Ethane 75
Ethionamide 32, 121, 156, 162, 163, 200
chemical structure of 206
Ewing sarcoma 49
Exertional dyspnea 16
Expectoration 30, 41, 155, 159, 242, 256, 262, 353
Extensive bilateral central bronchiectasis 174f, 212f
Extensively drug-resistant tuberculosis 136, 159, 161f
Extralobar sequestration 42
F
Fairy ring sign 5
Familian lymphedema 56
Farmer's lung 339
Fatigue 339
Feeding, oral 78
Fever 7, 77, 133, 142, 146, 155, 159, 216, 242, 251, 260, 277
high-grade 67
low-grade 30, 93, 99
moderate to high grade 44
recurrent 262
Fiberoptic bronchoscopy 39, 95, 253f, 261f, 269, 269f, 272f, 273f, 281f, 290f, 291, 292f, 297f, 298f, 300f, 301, 302f, 303, 305f, 312, 332f, 333f
Fibrosis
idiopathic
interstitial 347
pulmonary 349, 351
progressive massive 38
Filirasis 56
Fine-needle aspiration cytology 9, 11, 195
Fingers, clubbing of 334f
First-line antitubercular treatment 136f, 147f
Fistula, closure of 269f
Flexible bronchoscopy 294f
Fluoroquinolones 162
Forced expiratory volume 27
Forced vital capacity 27, 339, 351, 358
Functional endoscopic
sinus surgery 176
sinusoidal surgery 212
Fungal ball 19f, 89f, 90f, 209, 209f
G
Gastrointestinal tract 326
Gatifloxacin 162, 200
GeneXpert 99, 125, 136, 146, 155, 159
Gentamicin 44
Glandular hypertrophy 31
Gomori methenamine silver staining 8, 8f, 93
Gorham's syndrome 56
Gram's stain 82f
Granulation tissue 267f
Ground-glass
radiodensities 339f
shadows 354f, 355f
Gynecomastia 30f, 31f, 32
drug-induced 30
isoniazid-induced 30
H
Halo sign 96
reversed 5
Hands, dorsum of 61f
Heart surgery, congenital 79
Heller's myotomy, modified 169
Hemangioma, pleural 49
Hemoptysis 88, 247, 256, 260, 314, 322
moderate to massive 262
recurrent 7, 41, 208, 249, 256, 260, 271, 301, 303
Hermaphroditism 32
High-density mucus impaction 189f
High-resolution computed tomography 28, 180, 190, 212, 219, 351, 358
Hilar lymphadenopathy, bilateral 48f
Histamine phosphate 88
Hodgkin's lymphoma 49
Human immunodeficiency virus 4, 22, 24, 70
Hydatid cyst
pulmonary 275, 276
rupture of 271, 274f
Hydatid disease 275
Hydrocarbons 75
Hydropneumothorax 22, 222f
resolution of 223f
Hypernephroma 49
Hypertension 88, 110
Hypoalbuminemia 54, 77
Hypoplasia 35f, 36
pulmonary 86
Hypothyroidism 56
I
Imipenem 162, 163, 200
Immune
reconstitution inflammatory syndrome 24
system disorder 339
Infarction, pulmonary 5, 49
Infection
pleuropulmonary 49
recurrent 46
Inflammatory cells 335
Infliximab 356
Infrapulmonary effusion, right-sided 117, 117f
International Agency for Research on Cancer's 29
International Society for Human and Animal Mycology 192
International Union Against Tuberculosis and Lung Disease 195
Interstitial lung disease 347, 355
drug-induced 345, 347
Interstitial pneumonia, nonspecific 5
Interstitial pneumonitis, drug-induced 5
Intralobar sequestration 49
Invasive fungal pneumonias, diagnosis of 5
Isoniazid 30, 32, 107, 108, 112, 113, 115, 119, 123, 133, 136, 142, 155, 195, 196, 200, 216
high-dose 162, 163, 200
J
Jugular venous pressure 22
K
Kanamycin 119, 121, 125, 129, 134, 144f, 150f, 156, 162164, 200, 204
Kaposi's sarcoma 15, 56
Kawasaki disease 49
Klebsiella pneumonia 49
Klinefelter syndrome 32
L
Lactation 195
Langerhans cell histiocytosis, pulmonary 334, 335
Large-cell carcinoma 328, 330, 333
Larynx and cutaneous tuberculosis, tuberculosis of 63
Left hilar mass 324f
Left lung, collapse of 299f
Left pleural cavity 55
Lepra reaction 61f, 64
Leprosy 62, 63
diagnosis of 64
tuberculosis coinfection 64t, 65t
Leukemia 49
acute lymphoblastic 56
Levofloxacin 137, 143, 156, 162, 163, 200
Linezolid 162, 163, 200
Lipoid pneumonia 5
Liver 85
cirrhosis 49
disease 204
pre-existing 206
function test 159
Lobectomy 210
Low fat medium chain triglycerides 78
Lowenstein–Jensen culture 55
Lower lobe hypoplasia 34
Lung
abscess 45f, 282
adenocarcinoma 316
agenesis of 36
biopsy 340, 344
transbronchial 339
disease, restrictive 339
following lung abscess, herniation of 44
function data 27t
hernia 45
diagnosis of 45
injury, drug-induced 347
intralobar sequestration of 41
plasmacytoma 237
Lymph node 269, 314
fine-needle aspiration cytology of 295
mediastinal 101f, 283f, 296f, 304f
multiple caseating mediastinal 267f
paratracheal 283f
resolution of 23f
tracheobronchial 304f
Lymphadenitis, mediastinal 243f
Lymphadenopathy, mediastinal 23f, 303, 303f, 319f
Lymphangioleiomyomatosis 56
Lymphocytes 47
Lymphoma 49
Lymphomatoid granulomatosis 5
M
Magnetic resonance angiography 43
Magnetic resonance imaging 11, 169
thoracic angiography 35f
Malignancy, pleuropulmonary 49
Mammary tissue hyperplasia, bilateral benign 31
Mantoux test 167
Mass
heterogeneous 278f
intrathoracic 287f, 319f
left parahilar 289f
parahilar 289, 308f, 309f, 328f, 329f
paratracheal 287f
pulmonary 81, 190
Massive hemotysis, recurrent 262
Mediastinal fibrosis, radiation-induced 56
Mediastinal nodes 49
Meig's syndrome 49
Melanoma, malignant 49
Meropenem 162, 163, 200
Mesothelioma, malignant 49
Metastasis 49
Metastatic squamous cell carcinoma 314
Micafungin 21
Miliary tuberculosis 67
Mitogen-activated protein kinase 36
Modern antitubercular chemotherapy regimens 53
Modified Medical Research Council Scale 26
Moxifloxacin 156, 162, 163, 200
Mucopurulent expectoration 7
Mucormycosis 8
aseptate hyphae of 8f
pulmonary 4, 7, 8
Multidrug-resistant tuberculosis 107, 119, 121, 123, 125, 127, 129, 131, 133, 134f, 137f, 142, 146, 155, 156f, 157f
primary 121
regimen 133, 159
treatment 100f, 135f, 143f145f, 148f150f, 156f, 157f, 160f
Multinodular growth 302f, 305f
Multiple bullae 320f
Multiple encysted fluid pockets mimicking mass 216f
Multiple myeloma 12, 237, 239, 240t
diagnosis of 239
Multiple nodular
lesions 282, 283f285f
opacities 38f
shadows 187f
Multisystem disorder 101
Mycobacterium tuberculosis 24, 38, 42, 47, 55, 99, 110, 119, 121, 123, 125, 127, 129, 131, 133, 134, 136, 143, 147, 155, 159, 182, 199, 204, 208, 269
Myelolipoma, mediastinal 49
Myofibroblastoma 49
N
Nasal blockage, recurrent 176
Nasal discharge, recurrent 211
Neoplasm 88
Neuroendocrine tumors 326
Neutrophils 47
Nocardia asteroides 94
Nodal multiple myeloma 10
Nodule 244f
multiple 280f
Non-Hodgkin's lymphoma 49
Non-small cell lung
cancer 316
carcinoma 305, 333
O
Obstructive pneumonitis 242f, 303f, 304f
Octreoscan 265
Ofloxacin 200
Oral corticosteroids 101f, 356
Oral steroids 188f
treatment 172f, 173f
Orthopnea, history of 338, 341
Osteosarcoma 49
Ovarian tumors 49
P
Pancreatitis
acute 49
chronic 49
Para-aminosalicylic acid 119, 163, 196, 199, 204
Para-aortic lymphadenopathy 55
Paracoccidioidomycosis, pulmonary 5
Para-nasal sinuses, noncontrast computerized tomography of 213f
Paratracheal area, right 301f
Parenchymal opacity 48f
Paroxysmal nocturnal dyspnea 338, 341, 345
Pericardial effusion, resolution of 24f
Phenol 75
Pit and basket like appearance 250f
Pleural cavity, right 55
Pleural effusion 293, 296f
left-sided 47f, 312f
massive 330, 330f
recurrent 308
right-sided 353f
sarcoidosis-related 49
Pleural fluid 27, 55
adenosine deaminase activity 106
characteristics of 55t
cholesterol 55
culture 55
triglyceride 58
Pneumoconiosis 39
Pneumocystis carinii infection 14
Pneumonia 139, 245f
bacterial 49
community-acquired 67, 68
cryptogenic organising 5, 341, 344
Pneumonitis
chronic hypersensitivity 338
hypersensitivity 339
usual interstitial 356
Pneumothorax 2
primary spontaneous 2
right-sided 1f
spontaneous 1
treatment of 2
Positron emission tomography scan 306
Postcoronary artery bypass grafting 49
Potassium hydroxide 8
Potters rot 39
Prednisolone 62
oral 181f
Prednisone 239
Pregnancy 195
unusual complication of 1
Prophylactic cranial irradiation 326
Prostate 326
Protein 55
high 78
Prothionamide 162, 163
Pseudoachalasia 169
Pseudochylothorax 58, 58t
Pseudomonas aeruginosa 71, 82
Pulmonary aspergillosis, chronic necrotizing 1820
Pulmonary function test 71, 359
Purified protein derivative 22, 48, 60
Pyrazinamide 23, 30, 107, 108, 112, 113, 123, 133, 134, 136, 137, 142, 143, 155, 156, 162, 163, 200, 206, 216
R
Red blood cell count 47
Renal failure 32
chronic 49
Renal insufficiency 198
Respiratory distress 46
Rheumatoid arthritis 353, 354f, 355
associated interstitial lung disease 353
diagnosis of 354
Rhizopus oryzae 5
Rifabutin 200
Rifampicin 107, 108, 112, 113, 119, 123, 133, 136, 142, 155, 200, 206, 216
Rifapentine 200
Right upper lobe, collapse of 176, 176f
Rituximab 356
S
Sabouraud dextrose agar 8
Sandstorm appearance 220f
Sarcoidosis 47, 49, 56, 101
pulmonary 5
Scabies 53
Scanty sputum 26
Semi-invasive pulmonary aspergillosis 20
Sequestration, pulmonary 42
Serum glutaryl pyruvate transaminase 204
Signet ring appearance 212f
Silicosis 39
Sinus
signifying opacification of 213f
tuberculous 253f
Small-cell
carcinoma 318, 322, 324, 326, 333
lung cancer 326
Spine, magnetic resonance imaging of 11
Sputum positive pulmonary tuberculosis 129, 195
Squamous cell carcinoma 279, 282, 286, 289, 293, 295, 299, 301, 303, 305
Streptomycin 107, 108, 112, 113, 115, 119, 123, 133, 136, 162, 163
Subclavian vein 56
Subpulmonic pleural effusion 118
Sugar 55
Sulfamethoxazole 97
Superficial submucosal veins 287f, 288f
Superior vena cava
syndrome 49, 286
thrombosis of 56
Swelling
over face 286
upper limbs 286
Systemic lupus erythematosus 49
T
Tachypnea 93
Terizidone 162, 163, 200
Testosterone production, enzyme defects of 32
Thalassemia intermediate 49
Thalidomide 62
Thioacetazone 32, 108, 162
Thoracic aorta 42f
Thoracotomy 2
posterolateral 43
Thorax
computed tomography of 10, 11f, 23f, 35f, 36, 41, 44, 45f, 60, 62f, 74f, 78, 187, 188f, 211f, 217f, 233, 234f, 238, 252f, 260, 262, 343f
contrast-enhanced computed tomography of 85, 177f, 184f, 191f
high-resolution computed tomography of 88, 91f, 148f150f, 171, 174f, 181f, 183f, 186f, 220f, 271, 334, 356, 357
Thromboembolism, pulmonary 49
Thrombotic microangiopathies 49
Thyrotoxicosis 32
Toluene 75
Total leukocyte count 55, 67, 73
Total lung capacity 27
Trachea, anterolateral wall of 302f
Traction bronchiectasis 350f
Transbronchial needle aspiration 244f
Trimethoprim 97
Tropical pulmonary eosinophilia 222, 223
Tubercle bacillus 201
Tuberculosis 22, 24, 40, 54, 62, 63, 65, 105, 107t, 113, 163
concomitant pulmonary 60
endobronchial 242, 245
prevalence of 69
pulmonary 5, 7, 51, 119, 123, 147f
retreatment pulmonary 110
treatment of 106, 195, 198, 199, 204
tuberculosis, bilateral pulmonary 127, 131
Tuberculous lymphotracheal fistula 266
Tumor
malignant 49
multinodular 281f
pleural 49
U
Ultrasonography 35, 100, 233
Uremic pleuritis 49
V
Velcro crackles 351
Video-assisted thoracic surgery 43
Video-assisted thoracoscopic surgery 2
Vincristine 239
Voice, hoarseness of 301, 322
Voriconazole 21
W
Wegener's granulomatosis 5
Weight loss 125, 146, 277, 312, 322, 328, 339
White blood cell count 22
Z
Ziehl–Neelsen stain 8, 55, 93, 96f
modified 82, 83, 97
Zollinger–Ellison syndrome 264
×
Chapter Notes

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100 Cases in Pulmonary Medicine
100 Cases in Pulmonary Medicine
Authors Rajendra Prasad MD DTCD FAMS FCCP (USA) FRCP (Glasgow) FNCCP FICS FCAI FIAB FIMSA FCCS DSc (Honoris Causa) Director, Medical Education Professor and Head Department of Pulmonary Medicine Era's Lucknow Medical College and Hospital Era University Lucknow, Uttar Pradesh, India Formerly Director, Vallabhbhai Patel Chest Institute University of Delhi New Delhi, India Professor and Head, Department of Pulmonary Medicine King George's Medical University Lucknow, Uttar Pradesh, India Director, UP Rural Institute of Medical Sciences and Research Saifai, Etawah, Uttar Pradesh, India Nikhil Gupta MBBS MD (Medicine) Assistant Professor Department of General Medicine Dr Ram Manohar Lohia Institute of Medical Sciences Lucknow, Uttar Pradesh, India Co-author Harsh Saxena MBBS Junior Resident Department of Pulmonary Medicine Era's Lucknow Medical College and Hospital Lucknow, Uttar Pradesh, India Foreword Surinder K Jindal
Jaypee Brothers Medical Publishers (P) Ltd
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100 Cases in Pulmonary Medicine / Rajendra Prasad, Nikhil Gupta
First Edition: 2020
9789390020096
Printed at:
My teachers for their guidance, wisdom and inspiration, and
My parents, wife and children for their love and patience
FOREWORD
Diagnostic problems faced by a clinician remain the most exciting challenges in medical practice, more so in the field of pulmonary medicine. The physician makes the diagnosis essentially required to treat patients, effectively with the help of history and physical examination, supported by a variety of radiological images, physiological measurements, microbiological, histological and other relevant laboratory tests. In the context, the publication of this book on 100 cases in Pulmonary Medicine is a timely and useful addition in the existing literature on clinical practice. In this book, Dr Rajendra Prasad has presented diagnostic approach to 100 interesting and challenging cases in Pulmonary Medicine. He has also discussed the salient features of pathophysiology and clinical presentation. Various other aspects of diagnosis and treatment in light of current evidence based knowledge have been also deliberated upon. There are a large number of radiological images of interesting cases in this book which make its reading extremely interesting for clinicians treating pulmonary diseases.
Professor Rajendra Prasad is a nationally acclaimed chest physician and tuberculosis expert. He possesses more than four decades of illustrious experience with proven excellence in teaching, research and administrative activities. He is also a very popular medical teacher in pulmonary medicine. He is currently the Director, Medical Education, Professor and Head, Era's Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India. He has earlier served as Director of Vallabhbhai Patel Chest Institute, Delhi, India; Professor and Head, Department of Pulmonary Medicine King George's Medical University, Lucknow; and Director, UP Rural Institute of Medical Sciences and Research, Saifai, Etawah, Uttar Pradesh, India.
Dr Prasad has devoted his energy throughout his life in promoting medical education, patient care and research. His contribution in the field of Pulmonary Medicine, tuberculosis and multidrug-resistant tuberculosis (MDR-TB) are well recognized. His dynamic leadership in academic, patient care and administrative areas has earned him large number of awards from various international and national scientific societies including the prestigious Dr BC Roy National Award.
This comprehensive, well-referenced book contains plethora of knowledge and will remain a valuable educational source for undergraduate and postgraduate medical students, clinicians, healthcare workers caring for patients of chest diseases. I am quite hopeful that this book will help in better understanding of pulmonary diseases including tuberculosis. This handbook deserves a place in the library of every medical college and healthcare institutions.
Surinder K Jindal MD FCCP FAMS FNCCP
JINDAL CLINICS
Medical Director, Jindal Clinics, SCO 21, Sector 20 D, Chandigarh, India, 160020
Emeritus-Professor, Postgraduate Institute Medical Education and Research, Chandigarh, India
Blogspot: medicalviganettes.blogspot.in
PREFACE
It occurred to me that presentation of interesting cases in a concise format would provide valuable information that is difficult to find and not readily available in standard textbook for practicing physicians and PG students interested in diagnosis and management of pulmonary diseases. As a senior author of this book, I have come across many interesting cases in my more than 4 decades of clinical practice in Pulmonary Medicine. Of all those cases, I have compiled 100 Cases which are challenging and educative for general physician and consultants in medicine, pulmonary medicine and allied branches. These cases are collection of interesting case studies in day-to-day clinical practice of pulmonary medicine in Indian scenario. Each case follows a step-by-step approach which includes good history points, salient findings in physical examination and relevant investigations for diagnosis. There are a large number of radiological images of interesting cases which will make the reading extremely interesting. Treatment of cases is also discussed. Each case report is also followed by discussion of the salient features of pathophysiology, clinical presentation, diagnosis and treatment in light of current evidence-based knowledge. These interesting cases included various diffuse Parenchymal lung diseases, Tuberculosis including MDR and extensively drug-resistant tuberculosis (XDR-TB), Pleural diseases, Lung infection, Allergic bronchopulmonary aspergillosis and Thoracic malignancies. Cases with rare presentation such as Alveolar microlithiasis, Pulmonary sequestration, Chilaiditi syndrome, Endobronchial polyp, Carcinoid syndrome and Lympho tracheal fistula which are generally difficult to diagnose are also included. This book will be useful for both undergraduate and postgraduate medical students, general physicians, consultants in pulmonary medicine and allied branches interested in diagnosis and treatment of pulmonary diseases.
Rajendra Prasad
ACKNOWLEDGMENTS
As a senior author of this book, I wish to acknowledge my indebtedness to a number of people who significantly contributed to the publication of this book. The individual to whom I would like to acknowledge first is Late Professor BK Khanna who as a Head of Department of Tuberculosis at the King George's Medical College, Lucknow, Uttar Pradesh, India, while I was postgraduate student in that department, markedly stimulated my interest in tuberculosis and other chest diseases. Professor BK Khanna's own tremendous knowledge and wisdom in the field of tuberculosis set an example of thoughtfulness and meticulousness which I have always tried to emulate. I am also indebted to Professor PK Mukherjee, Late Dr MS Agnihotri, Late Dr Jafar Jameel and Late Dr J Nath, for their great inspiration as teachers during my postgraduate days. I am greatly indebted to many postgraduate students who have been trained with me in the department at King George's Medical College, Lucknow; Vallabhbhai Patel Chest Institute, Delhi, India, and Era's Lucknow Medical College and Hospital, Lucknow, especially Dr Sanjay Verma, Dr Kiran Vishnu Narayan, Dr Suneesh C Anand, Dr Giridhar BH, Dr Abhijeet, Dr Abhishek Agrawal, Dr Saurabh Karmakar, Dr Mandeep Singh, Dr Pawan Gupta, Dr Visweswaran Balasubramanian, Dr Faizan Ahmad, Dr Amitabh Banka, Dr Sakshi Batra, Dr Ronal Naorem, and Dr Asna Khan, Dr Harsh Saxena, Dr Rishabh Kacker, Dr Huda Shamim, Dr Syed Ahmed Hussain Kazmi, Dr Mohammad Tanzeem and Dr Tanmay Bhargava. The efforts of these postgraduate students in part is responsible for generating much of the data that can be incorporated in making the chapters in book more evidence based.
I also wish to express my appreciation to Dr Nikhil Gupta, for helping me in preparing and correcting the manuscript. I also wish to express my special appreciation Dr Harsh Saxena my PG Student, Era's Lucknow Medical College and Hospital for providing tremendous help in preparing the cases. I also wish to express my thanks Miss Seema Shukla, Mr Gyan Prakash and Mr Mithun, for their invaluable help in the preparation and typing of manuscript. I am also thankful to all my patients, who gave me experience in the field of Pulmonary Medicine.
I am very grateful to the whole team of M/s Jaypee Brothers Medical Publishers (P) Ltd, who helped and guided me, Shri Jitendar P Vij, Mr Ankit Vij, Dr Richa Saxena, Ms Pooja Bhandari, Ms Sunita Katla and team members for all their support to work in this project and make it a success. Without their co-operation, I could not have completed this project.