Optical Coherence Tomography—Atlas and Text Samuel Boyd, Rosario Brancato, Bradley Straatsma
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1OPTICAL COHERENCE TOMOGRAPHY ATLAS AND TEXT
EDITORS: SAMUEL BOYD, MD ROSARIO BRANCATO, MD BRADLEY STRAATSMA, MD
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© Copyright, English Edition, 2009 for Jaypee - Highlights Medical Publishers, Inc.
All rights reserved and protected by Copyright. No part of this publication may be reproduced, stored in retrieval system or transmitted in any form by any means, photocopying, mechanical, recording or otherwise, nor the illustrations copied, modified or utilized for projection without the prior, written permission of the copyright owner.
Due to the fact that this book will reach ophthalmologists from different countries with different training, cultures and backgrounds, the procedures and practices described in this book should be implemented in a manner consistent with the professional standards set for the circumstances that apply in each specific situation. Every effort has been made to confirm the accuracy of the information presented and to correctly relate generally accepted practices. The authors, editors, and publisher cannot accept responsibility for errors or exclusions or for the outcome of the application of the material presented herein. There is no expressed or implied warranty for this book or information imparted by it.
Any review or mention of specific companies or products is not intended as an endorsement by the authors or the publisher.
Boyd, Samuel, MD; Brancato, Rosario, MD; Straatsma, Bradley, MD.
“OPTICAL COHERENCE TOMOGRAPHY - ATLAS AND TEXT”
9789962678045
Published for: Jaypee - Highlights Medical Publishers, Inc.
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Editors Samuel Boyd, M.D. Editor in Chief and Executive Vice President, HIGHLIGHTS OF OPHTHALMOLOGY. Director, Laser Section and Associate Director, Retina and Vitreous Department, Clinica Boyd - Ophthalmology Center, Panama, Rep. of Panama Rosario Brancato, M.D. Professor of Ophthalmology Director of the School of Ophthalmologic Specialization. San Raffaele University Hospital, Milan, Italy Bradley Straatsma, M.D. Professor and Director Emeritus, Jules Stein Eye Institute University of California, Los Angeles (UCLA) Los Angeles, California, U.S.A. 4Contributing Authors 11Foreword
Optical Coherence Tomography (OCT) is a technology that has come of age. From a laboratory tool for performing a single A-scan, to a research device for creating cross-sectional images of ocular tissues in vivo, OCT has evolved into a clinical instrument that is used to detect and direct the treatment of glaucoma, retinal diseases and anterior segment pathologies. This technology continues to evolve, and the current volume explores current and future uses for OCT.
The current compilation covers the use and interpretation of OCT, the applications of OCT in ophthalmology, including uses in the anterior segment and retina. OCT in the diagnosis and management of glaucoma and age related macular degeneration are described. In addition, the integration of OCT and fluorescein angiography is discussed, as well as the use of OCT in the diagnosis and management of ocular tumors.
Newer iterations of OCT permit three dimensional imaging, due to advances that allow very high speed, high resolution capture of images. Instead of 400 A-scans per second that were possible with conventional, or time-domain OCT, spectral domain OCT enables the acquisition of 20,000 – 40,000 A-scans per second. These three dimensional OCT images present opportunities and challenges. Improvements in resolution may lead to increased reproducibility, sensitivity and specificity. Three dimensional OCT (3D OCT) permits the creation of an OCT fundus image, which facilitates precise image registration. The higher resolution allows segmentation and mapping of intraretinal layers. Newer versions of OCT improve visualization of tissues relevant in the detection and management of ocular disease. On the other hand, 3D OCT creates very large data sets, and optimal methods for analysis are still in the process of being created.
OCT is a robust technology that continues to evolve. OCT is a useful tool for diagnosis and management of eye diseases and may provide a cost effective diagnostic utility for basic and clinical studies of eye diseases. Of course, the ultimate goal is the earliest possible detection of a disease and its progression in order to prevent visual loss in our patients.
Joel S. Schuman, MD, FACS
Eye and Ear Foundation Professor and
Chairman, Department of Ophthalmology
University of Pittsburgh School of Medicine
Director, UPMC Eye Center
Professor of Bioengineering
Swanson School of Engineering, University of Pittsburgh
Professor, Center for the Neural Basis of Cognition
Carnegie Mellon University and University of Pittsburgh.
Pittsburgh, Pennsylvania, U.S.A.