Table of Content

2017 | January-March | Volume 3 | Issue 1

ORIGINAL ARTICLE

Daniel T. Lackland, Mark Niebylski

Editorial

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:1] [Pages No:0 - 0]

GET ACCESS  |  DOI: 10.5005/htnj-3-1-iv  |  Restricted |  How to cite  | 

REVIEW ARTICLE

Norm RC Campbell

Recommended Standards for assessing Blood Pressure in Human Research where Blood Pressure or Hypertension is a Major Focus

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:6] [Pages No:1 - 6]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0062  |  Restricted |  How to cite  | 

Abstract

How to cite this article

Campbell NRC. Recommended Standards for assessing Blood Pressure in Human Research where Blood Pressure or Hypertension is a Major Focus. Hypertens J 2017;3(1):1-6.

BLOOD PRESSURE MECHANISM

Uday M Jadhav, R Chandni

Salt Intake and Blood Pressure Levels: Is the Concept Valid?

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:5] [Pages No:7 - 11]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0063  |  Restricted |  How to cite  | 

Abstract

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Chandni R, Jadhav UM. Salt Intake and Blood Pressure Levels: Is the Concept Valid? Hypertens J 2017;3(1):7-11.

TRENDS IN HYPERTENSION TREATMENT GOALS

C Shaun Wagner, Brent M Egan, Jiexiang Li

Controlling Systolic Blood Pressure below 140 mm Hg in Most Hypertensive Patients matches Systolic Blood Pressure Intervention Trial Intensive Treatment: Practical Implications for Patient Care

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:8] [Pages No:12 - 19]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0064  |  Restricted |  How to cite  | 

Abstract

How to cite this article

Egan BM, Li J, Wagner CS. Controlling Systolic Blood Pressure below 140 mm Hg in Most Hypertensive Patients matches Systolic Blood Pressure Intervention Trial Intensive Treatment: Practical Implications for Patient Care. Hypertens J 2017;3(1):12-19.

SECONDARY HYPERTENSION

Sreenivas K Arramraju

Secondary Causes of Hypertension: Illustrative Cases

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:3] [Pages No:20 - 22]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0065  |  Restricted |  How to cite  | 

Abstract

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Arramraju SK. Secondary Causes of Hypertension: Illustrative Cases. Hypertens J 2017;3(1):20-22.

HYPERTENSION AND HORMONAL STATUS

Bharti Maheshwari, Anuj Maheshwari

Hypertension and Menopause

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:4] [Pages No:23 - 26]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0066  |  Restricted |  How to cite  | 

Abstract

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Maheshwari A, Maheshwari B. Hypertension and Menopause. Hypertens J 2017;3(1):23-26.

BLOOD PRESSURE MECHANISM

Narsingh Verma

Sympathetic Nervous System and Hypertension

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:10] [Pages No:27 - 36]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0067  |  Restricted |  How to cite  | 

Abstract

Aim

The review emphasizes on the sympathetic and parasympathetic abnormalities in essential hypertension, the possible mechanisms underlying these abnormalities, and their importance in the development and progression of the structural and functional cardiovascular (CV) damage that characterizes hypertension.

Background

Apart from being a hemodynamic phenomenon, primary hypertension is a vicious syndrome involving abnormal adiposity, overactivation of the adrenergic system, metabolic abnormalities, and activation of the immune system. Physiological studies have established the key role played by the autonomic nervous system in modulating CV functions and in controlling arterial pressure values. Many factors contribute to increased sympathetic nerve activity in metabolic abnormalities including obesity, impaired baroreflex sensitivity, hyperinsulinemia, and elevated adipokine levels.

Review results

Experimental and clinical investigations clearly indicate that the origin, progression, and outcome of hypertension are related to dysfunction of the autonomic CV system, especially to abnormal activation of the adrenergic division. The activation of the sympathetic nervous system is essential in energy homeostasis and can exert intense metabolic effects. Accumulating data from a number of studies suggest that central sympathetic overactivity plays a crucial role in the causative factors and complications of several metabolic conditions that can cluster to form the metabolic syndrome.

Conclusion

This review provides an evidence of attenuation of autonomic CV control in essential hypertension and that sympathetic overdrive is a major component of this autonomic dysregulation. Arterial pressure control requires complex integration of regulatory mechanisms across multiple physiological systems. A continuous increase in blood pressure therefore, reflects a failure of one or more of these controls.

Clinical significance

The findings discussed herein provide a rationale for pursuing sympathetic deactivation by nonpharmacological as well as pharmacological interventions aimed at lowering elevated blood pressure values and protecting patients from hypertension-related complications.

How to cite this article

Verma N. Sympathetic Nervous System and Hypertension. Hypertens J 2017;3(1):27-36.

CLINICAL MANAGEMENT

Clarence E Grim

Potassium and Blood Pressure: How to Test the Effects of DASH Diet in your Patient with Hypertension?

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:5] [Pages No:37 - 41]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0068  |  Restricted |  How to cite  | 

Abstract

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Grim CE. Potassium and Blood Pressure: How to Test the Effects of DASH Diet in your Patient with Hypertension?. Hypertens J 2017;3(1):37-41.

HISTORICAL VIGNETTES

Rajeev Agarwala

A Chapter from History

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:2] [Pages No:42 - 43]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0069  |  Restricted |  How to cite  | 

Abstract

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Agarwala R. A Chapter from History. Hypertens J 2017;3(1):42-43.

THERAPEUTIC

Mohsin Wali, C Venkata S Ram

Device-based Therapies for Resistant Hypertension: Current Status

[Year:2017] [Month:January-March] [Volume:3] [Number:1] [Pages:6] [Pages No:44 - 49]

GET ACCESS  |  DOI: 10.5005/jp-journals-10043-0070  |  Restricted |  How to cite  | 

Abstract

How to cite this article

Wali M, Ram CVS. Device-based Therapies for Resistant Hypertension: Current Status. Hypertens J 2017;3(1):44-49.

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