Noninvasive ventilation (NIV) therapy has become the standard of care for home therapy of patients suffering from sleep apnea and chronic Type 2 respiratory failure. We did a retrospective study of a patient admitted with the exacerbation of these disease despite of being advised home NIV therapy. The study was performed in a tertiary care institute in the past 2 years. A total of 186 patient of chronic respiratory failure were studied who were prescribed NIV, out of which 96 patients who adhered to NIV were followed, and reasons of readmission and practical issues were studied. All the patient admitted to respiratory and general intensive care unit (ICU) were included, who needed a stay of more than 5 days. Out of 96 patients, 30 patients are of severe sleep apnea, and 25 patients are of severe chronic obstructive pulmonary disease (COPD). The most common cause of such patients going into respiratory failure after use of NIV being recurrent infection and poor willingness to continue with NIV due to psychological and medical reasons. Commonly seen medical reasons were ulcer over the bridge of the nose; inability to sleep with a mask on and feeling of suffocation with the mask. Psychological reasons include depression symptoms and a feeling of loneliness. We recorded that patient with regular follow up; the active role played by younger family members and patient on nasal mask had better outcome results as compared to their medical counterparts.

Background: Sleep is an indicator of health. Sleep determine many aspects of our life like mood, cognitive functions such as attention and working memory, homeostasis, learning, concentration, etc. Sleep is very essential for the academic progress in college students, whereas most of the sleep-related problems are found in college students worldwide. Aim: This study aimed to evaluate the positive effect of sleep special technique (SST) on sleep quality, stress level and quality of life in young healthy yoga practitioners. Materials and Methods: A total of 120 healthy male yoga practitioners were screened and N = 94 were randomly allocated into two groups, experimental group N = 47, and control group N = 47. Experimental group practiced 1 month of (SST), and the control group had no exposure to SST. Variables Measured: Pittsburgh sleep quality index (PSQI), perceived stress scale (PSS), World Health Organization quality of life–BREF (WHOQOL–BREF), and the vedic personality inventory (VPI) Results: After one month of SST result showed the significant reduction of the global PSQI score (p < 0.001), perceived stress scale (p < 0.001), and considerable improvement in all domains of QOL (p < 0.001), Sattva guna (p < 0.001) in the experimental group compared to the control group. Conclusion: A one-month course of SST has a significantly positive effect on overall sleep quality, quality of life and perceived stress. The transition towards sattva guna was evident during the course of SST intervention.

Obstructive sleep apnea (OSA) is a sleep-related breathing disorder (SRBD) hallmarked by upper airway collapsibility and obstruction leading to nocturnal hypoxia and sleep arousals. Diabetes mellitus (DM) is a chronic medical malady which stems from an aberration in the glucose metabolism leading to multisystemic complications and eventually ends organ damage. Both these disorders are independently major public health concerns by virtue of their momentous morbidity, mortality and healthcare albatross. The liaison between these two leviathans is enigmatic and multifarious. Prima facie they share a common predisposing factor of obesity. OSA is associated with impairment of glucose metabolism and predisposes the individual to the development of DM. Moreover DM serves as a risk factor for OSA in conjunction with the other components of the metabolic syndrome. Untreated DM leads to aggravation of the severity of OSA while untreated OSA leads to suboptimal glycemic control and propagates complications of DM. This intricate relationship between DM and OSA is a fertile and deficiently fathomed terrain for contemplative research. We hereby make a humble endeavor to decipher and simplify the Daedalean association.

Pulmonary embolism (PE) is a major manifestation of venous thromboembolism (VTE). Obstructive sleep apnea (OSA) leads to hypercoagulable state and may be associated with recurrent PE in the absence of deep vein thrombosis (DVT). Early identification and treatment of OSA may be helpful in reducing the recurrence of PE. Here, we report a case of OSA presenting with isolated PE without DVT with a brief mention of therapeutic implications.