Mundi R, Mundi S, Bhandari M. Evidence-based Medicine: Top Ten Things to Know! J Postgrad Med Edu Res 2012;46(1):1-3.

Hussain N, Turvey S, Bhandari M. Keeping up with Best Evidence: What Resources are Available? J Postgrad Med Edu Res 2012;46(1):4-7.

Chaudhry H, Bhandari M. Research made Easy: Answering Important Questions with Valid Designs. J Postgrad Med Edu Res 2012;46(1):8-11

Sohani Z. Meta-analysis: Statistical Trickery or Sound Science? J Postgrad Med Edu Res 2012; 46(1):12-14.

To assess sociodemographic profile of roadside accident victims.

Using purposive sampling technique 100 patients were enrolled in the study. A questionnaire consisting of personal identification data, personal habits and details related to occurrence of accident was used to collect the data.

More than half subjects (59%) were in age group of 20 to 40 years with mean age being 36.5 years ± 14.2. Majority of the accident victims (84%) were male. More than half (67%) belonged to Hindu religion, educated up to secondary level (65%), were married (54%) and were rural habitants (54%). Twenty-six percent of subjects had the history of drinking alcohol. Out of these 15 subjects (57.7%) had consumed alcohol at the time of accident. Sixty-eight percent were driving two wheeler; only 27% were wearing protective equipment (helmet/seat belt) at the time of accident. Approximately one-third (39%) had 6 to 15 years of driving experience. Half (51%) of the accidents occurred in evening hours and on Saturday and Sunday.

The present study reflects that there is need to plan strategies to decrease risk of accidents and inculcate healthy driving habits in the vulnerable citizens.

Aggarwal A, Kaur S, Dhillon MS. Sociodemographic Profile of Road Traffic Accident Victims Admitted at Emergency Surgical OPD of a Tertiary Care Hospital. J Postgrad Med Edu Res 2012;46(1):15-18.

There have been numerous studies and reviews indicating that caffeine ingested before exercise causes rapid and significant improvement in performance, especially in aerobic capacity. Even though caffeine has a half life of 4 to 6 hours that implies high level of caffeine will be in the blood for up to 3 to 4 hours after ingestion, most studies on exercise performance are at 1 hour after ingestion.

To assess the efficacy of 300 mg of caffeine and placebo ingestion at 1 hour, 1 hour 30 minutes, 2 hours, 2 hours 30 minutes, 3 hours in improvement of isometric muscle strength in human quadriceps muscle, cardiorespiratory endurance and to find that which of the duration produce best result.

Experimental study with different subject design. Twenty subjects with equal number of boys and girl (age 20-30 years, weight 60-65 kg) were recruited to participate in the study. They were randomly allocated to experimental and placebo group. Pre- and postquadriceps muscle strength and time to exhaustion at 65% of VO_2max was recorded.

The results showed significant improvement (p < 0.001) in strength and endurance at all five durations in experimental group. Results were significant (p < 0.05) when caffeine and placebo groups were compared. The percentage improvement for strength and endurance was higher at 1st and 2nd hours when compared to 3rd hours duration.

The effects of caffeine are highest till 2 hours of ingestion after that wean off effects are seen.

Sandhu JS, Shenoy S, Dutt I. Time Dose Relation of Caffeine Ingestion on Muscular Strength and Endurance Performance. J Postgrad Med Edu Res 2012; 46(1):19-23.

To perform a qualitative assessment of research publications coming from two premier medical institutes in India.

Research publications from AIIMS and PGIMER published during 2004 to 2008 were analyzed. The publications were categorized into five types. A year-wise analysis was done for both the institutes. Data was obtained from Scopus. The collected data included the number of papers published in a category, total citations received by a type of publication in a year, number of publications which have no citations, number of publications with only one citation, h-index, number of zero and only one citation were added to get publications with negligible citations.

A total number of 4,828 and 2,882 research publications were analyzed from AIIMS and PGIMER respectively. The original articles attracted highest no of citations that is 64 and 66% of the total citations in a year for AIIMS and PGIMER respectively. Approximately 37 to 42% of the original articles get negligible citations. The h-index for various categories of article was higher for the original articles (18/13), whereas it was very low for other category of research publications.

The original articles fetch more citations in long run. Close to 40% of the original research done in the studied institutes get negligible citations pointing toward their outcome utility and quality. More than 60% of the minor category publications remain uncited. This sort of data if periodically obtained should serve as a benchmark for quality analysis of scientific research.

Kanojia RP, Rathod KK, Rao KLN. Qualitative Assessment of Research done at Two Premier Medical Institutes in India: Some Data for Introspection. J Postgrad Med Edu Res 2012;46(1):24-33.

Lung metastases from Ewing sarcoma have traditionally been treated with whole-lung irradiation (WLI) and chemotherapy. WLI may unnecessarily treat uninvolved normal lung tissue and increase the risk of toxicity. Stereotactic body radiotherapy (SBRT) has proven to be a safe and effective treatment for primary lung cancer and lung metastases, but there is no significant published description of SBRT in lung metastases from Ewing sarcoma.

The patient presented in this case report had long-term survival from lung metastases of Ewing sarcoma treated with chemotherapy and SBRT. SBRT may prove to be safer and more effective than whole lung irradiation as a treatment of lung metastases in Ewing sarcoma.

Whether SBRT of lung metastases of Ewing sarcoma can improve outcomes and decrease toxicity compared to whole-lung irradiation, surgical resection or palliative chemotherapy merits further study.

Rahn DA, Read W, Sandhu A. Treatment of Lung Metastases from Ewing Sarcoma with Stereotactic Body Radiotherapy rather than Whole-Lung Irradiation. J Postgrad Med Edu Res 2012;46(1):34-36.

Rao C, Sharma A, Rana SS, Bhauwala A, Singh S, Singh K, Bhasin DK. Massive Obscure Overt Gastrointestinal Bleed: An Unusual Cause diagnosed by Capsule Endoscopy. J Postgrad Med Edu Res 2012;46(1):37-39.

Kaur S, Rajagopalan S, Shafiq N, Dogra S, Pandhi P, Malhotra S. A Case of Drug-induced Toxic Epidermal Necrolysis: Pharmacovigilance in Action and Lessons to learn. J Postgrad Med Edu Res 2012;46(1):40-42.

A 45-year-old male patient had a tender 2 week swelling of 4 × 5 cm on medial right proximal calf. A 26-year male presented with discomfort and diffuse 6 cm swelling at inner left forearm. In both ultrasound showed characteristic hypoechoic cyst with hyperechoic scolex, and MRI revealed isolated cyst surrounded by inflamed muscles. FNAC confirmed cysticercosis, and the patient responded to oral albendazole (3 weeks) with oral steroids (2 weeks).

Although rare, possibility of isolated muscular cysticercosis should always be considered in any small musculoskeletal soft tissue swelling presenting with nonspecific clinical findings. Both our patients responded to medical therapy and were disease free, as confirmed at 3 months by follow-up MRI. These cysts can be confidently diagnosed on the basis of ultrasound and MRI, and can be very well-treated nonsurgically with an oral drug regimen consisting of albendazole and steroid.

Rangdal SS, Prabhakar S, Dhatt S S, Prakash M, Dhillon MS. Isolated Muscular Cysticercosis: A Rare Pseudotumor and Diagnostic Challenge, can It be treated Nonoperatively? A Report of Two Cases and Review of Literature. J Postgrad Med Edu Res 2012;46(1):43-48.

Bhattacharya A, Agrawal KL, Kashyap R, Manohar K, Mittal BR, Varma SC, Dey P, Das A. Coexisting Tuberculosis and Non-Hodgkin's Lymphoma on ¹⁸F-Fluorodeoxyglucose PET-CT. J Postgrad Med Edu Res 2012;46(1):49-50.