More K, Badade ZG, Narshetty JG, Joshi DS, Mukherjee S, Deepak AD, Badade VZ. Lipid Peroxidation, Sperm DNA Fragmentation Total Antioxidant Capacity and Semen Quality in Male Infertility. MGM J Med Sci 2014;1(1):1-6

herbs have been used as medicines since ancient times and it has been observed that human body is well suited to herbal remedies. In the present study, the myocardial salvaging effects of Bacopa monnieri (L) Pennell (Scrophulariaceae) (Bm), a medicinal herb was evaluated in diabetes mellitus.

Type II diabetes mellitus was induced chemically in rats using streptozotocin (STZ) (65 mg/kg). Wistar rats were randomly allocated to sham, STZ control and Bm treated groups. Lyophilized hydro-alcoholic extract of Bm (75 mg/kg) was administered once a day orally to the rats for 21 days. On the 22nd day, biochemical parameters (fasting blood sugar and creatinine phosphokinase [(CPK), CPK-MB] and histopathological assessment of myocardium was undertaken to evaluate the cardioprotective efficacy of Bm.

Pretreatment of Bm to experimental rats restored the raised fasting blood sugar levels, CPK, CPK-MB activity and preserved the histopathological architecture of pancreas, heart, liver and kidney as compared to the STZ control group. Bm demonstrated significant cardioprotective effects in the experimental model of diabetic mellitus.

Bm demonstrated significant myocardial salvaging effects in the presence of diabetes mellitus. Histopathological assessment of myocardium shows the cardioprotective effects of Bm in the STZ model of diabetes mellitus.

Ghatage AJ, Mohanty IR, Maheswari U, Suman RK, Urhekar AD, Deshmukh Y. Cardioprotective Efficacy of Bacopa monniera in Experimental Diabetes Mellitus: Biochemical and Histopathological Assessment. MGM J Med Sci 2014;1(1):7-12.

Thakur M, Dayal N, Pai G, Joshi D. Toxicity Assessment of Silver Nanoparticles in Zebrafish Embryos. MGM J Med Sci 2014;1(1):13-17

The aim of the present study was to evaluate the triglyceride/HDL-C ratio as a surrogate marker of IR in metabolic syndrome patients.

Total 110 patients were recruited in the study after obtaining informed written consent. They were divided into two groups. Group I included healthy controls (n = 50) and subjects with metabolic syndrome (MS) (n = 60) as per NCEP ATP III criteria were included in group II. Anthropometric measurements and biochemical analysis was performed in all subjects.

There was statistically significant difference in anthropometric, glycemic and lipid parameters in control and study group (p < 0.0001). The regression model between HOMA-IR and TG/HDL-C ratio showed was positive correlation (r = 0.29, p = 0.01) while between QUICKI and TG/HDL-C ratio showed negative correlation (r = –0.37, p = 0.002).

We report in our study that TG/HDL-C can be adopted in routine laboratory practice as a surrogate marker for prediction of insulin resistance. So that patients with metabolic syndrome may be beneficial at an early stage.

Samant P, Chavan P, Rai S. TG/HDL-C Ratio: A Surrogate Marker of Insulin Resistance in Patients with Metabolic Syndrome. MGM J Med Sci 2014;1(1):18-21.

Garfield RE, Lucovnik M, Kuon RJ. Diagnosis and Effective Management of Preterm Labor. MGM J Med Sci 2014;1(1):22-37.

Saha KK, Kaul SK. Antithrombotic Therapy in Patients Postcardiac Interventions. MGM J Med Sci 2014;1(1):38-40.

Kale AV, Kakade JR, Engade MB, Chinthireddy SR. Rare Presentation of Large Cell Lymphoma. MGM J Med Sci 2014;1(1):41-43

Taksali R, Pal NS, Mulay SS. Complicated Hyperuricemia. MGM J Med Sci 2014;1(1):44-46.