About Video

The set of video clips represent two cases of Ross’ syndrome. Note the absence of ankle and knee jerks, tonic pupils and lack of sweating in one half of the body in the lady. Ross’ syndrome is a constellation of Holmes-Adie’s syndrome, consisting in myotonic pupils and absent deep tendon reflexes and segmental anhidrosis, usually unilaterally. This is clinically manifested as hyperhidrosis in the other side. Gordon Holmes described the areflexia while John Adie, his Registrar described the pupillary changes in the first half of the 20th century. AT Ross described the anhidrosis in 1958. It has been said that it results from a complex and progressive involvement of cutaneous sensory and autonomic innervations, which leads to an altered heat regulation in the body. Thus it is a disease of impaired thermoregulation.